Magnesium in PDB 7x0z: Cryo-Em Structure of Human ABCD1 E630Q in the Presence of Atp and Magnesium in Outward-Facing State

The binding sites of Magnesium atom in the Cryo-Em Structure of Human ABCD1 E630Q in the Presence of Atp and Magnesium in Outward-Facing State (pdb code 7x0z). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Cryo-Em Structure of Human ABCD1 E630Q in the Presence of Atp and Magnesium in Outward-Facing State, PDB code: 7x0z:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Cryo-Em Structure of Human ABCD1 E630Q in the Presence of Atp and Magnesium in Outward-Facing State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of Human ABCD1 E630Q in the Presence of Atp and Magnesium in Outward-Facing State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg801 b:27.1 occ:1.00 OG A:SER514 2.0 26.0 1.0 O1G A:ATP802 2.2 37.3 1.0 OE1 A:GLN544 2.7 23.9 1.0 OD1 A:ASP629 2.8 25.2 1.0 O1B A:ATP802 2.9 37.3 1.0 CD A:GLN544 3.3 23.9 1.0 CB A:SER514 3.4 26.0 1.0 PG A:ATP802 3.6 37.3 1.0 NE2 A:GLN630 3.7 27.6 1.0 NE2 A:GLN544 3.7 23.9 1.0 CG A:ASP629 3.7 25.2 1.0 OD2 A:ASP629 3.8 25.2 1.0 N A:SER514 4.0 26.0 1.0 PB A:ATP802 4.0 37.3 1.0 CG2 A:ILE657 4.0 25.4 1.0 O3B A:ATP802 4.1 37.3 1.0 CA A:SER514 4.1 26.0 1.0 O3G A:ATP802 4.2 37.3 1.0 CD A:GLN630 4.3 27.6 1.0 CG A:GLN544 4.4 23.9 1.0 CE A:LYS513 4.5 28.0 1.0 O2B A:ATP802 4.6 37.3 1.0 CB A:GLN544 4.6 23.9 1.0 O2G A:ATP802 4.7 37.3 1.0 CB A:LYS513 4.7 28.0 1.0 CG A:GLN630 4.7 27.6 1.0 CD1 A:ILE657 4.9 25.4 1.0 C A:LYS513 4.9 28.0 1.0 OE1 A:GLN630 5.0 27.6 1.0

Magnesium binding site 2 out of 2 in the Cryo-Em Structure of Human ABCD1 E630Q in the Presence of Atp and Magnesium in Outward-Facing State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Cryo-Em Structure of Human ABCD1 E630Q in the Presence of Atp and Magnesium in Outward-Facing State within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg801 b:27.8 occ:1.00 OG B:SER514 2.1 25.3 1.0 OE1 B:GLN544 2.1 23.9 1.0 O3B B:ATP802 2.8 28.0 1.0 CB B:SER514 2.9 25.3 1.0 CD B:GLN544 3.3 23.9 1.0 O1G B:ATP802 3.6 28.0 1.0 O2A B:ATP802 3.8 28.0 1.0 PB B:ATP802 3.8 28.0 1.0 PG B:ATP802 3.9 28.0 1.0 O1B B:ATP802 3.9 28.0 1.0 N A:GLY607 4.0 23.9 1.0 NE2 B:GLN544 4.0 23.9 1.0 OD2 B:ASP629 4.2 26.8 1.0 CA B:SER514 4.2 25.3 1.0 O3A B:ATP802 4.2 28.0 1.0 CB B:GLN544 4.3 23.9 1.0 CG B:GLN544 4.3 23.9 1.0 N B:SER514 4.4 25.3 1.0 PA B:ATP802 4.5 28.0 1.0 OD1 B:ASP629 4.5 26.8 1.0 CA A:GLY607 4.7 23.9 1.0 O1A B:ATP802 4.7 28.0 1.0 CG B:ASP629 4.8 26.8 1.0 CA A:SER606 4.8 25.5 1.0 O3G B:ATP802 4.8 28.0 1.0 CB A:SER606 4.8 25.5 1.0 C A:SER606 4.9 25.5 1.0 O2G B:ATP802 5.0 28.0 1.0

C.Xiong, L.N.Jia, W.X.Xiong, X.T.Wu, L.L.Xiong, T.H.Wang, D.Zhou, Z.Hong, Z.Liu, L.Tang. Structural Insights Into Substrate Recognition and Translocation of Human Peroxisomal Abc Transporter Aldp. Signal Transduct Target Ther V. 8 74 2023.
ISSN: ESSN 2059-3635
PubMed: 36810450
DOI: 10.1038/S41392-022-01280-9