Magnesium in PDB 7x24: Cryo-Em Structure of Non Gastric H,K-Atpase ALPHA2 Spwc Mutant in (2K+)E2-Alf State

All present enzymatic activity of Cryo-Em Structure of Non Gastric H,K-Atpase ALPHA2 Spwc Mutant in (2K+)E2-Alf State:
7.2.2.13; 7.2.2.19;

The structure of Cryo-Em Structure of Non Gastric H,K-Atpase ALPHA2 Spwc Mutant in (2K+)E2-Alf State also contains other interesting chemical elements:

Potassium	(K)	3 atoms
Aluminium	(Al)	1 atom
Fluorine	(F)	4 atoms

The binding sites of Magnesium atom in the Cryo-Em Structure of Non Gastric H,K-Atpase ALPHA2 Spwc Mutant in (2K+)E2-Alf State (pdb code 7x24). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Cryo-Em Structure of Non Gastric H,K-Atpase ALPHA2 Spwc Mutant in (2K+)E2-Alf State, PDB code: 7x24:

Magnesium binding site 1 out of 1 in the Cryo-Em Structure of Non Gastric H,K-Atpase ALPHA2 Spwc Mutant in (2K+)E2-Alf State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of Non Gastric H,K-Atpase ALPHA2 Spwc Mutant in (2K+)E2-Alf State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1112 b:17.8 occ:1.00 F1 A:ALF1111 2.1 17.5 1.0 OD2 A:ASP388 2.1 17.1 1.0 O A:THR390 2.1 14.5 1.0 OD1 A:ASP729 2.5 12.9 1.0 F3 A:ALF1111 2.6 17.5 1.0 AL A:ALF1111 3.1 17.5 1.0 CG A:ASP388 3.3 17.1 1.0 C A:THR390 3.3 14.5 1.0 CG A:ASP729 3.6 12.9 1.0 OD1 A:ASP388 3.8 17.1 1.0 OD2 A:ASP729 4.1 12.9 1.0 O A:GLY232 4.1 24.7 1.0 CA A:THR390 4.1 14.5 1.0 CB A:THR390 4.3 14.5 1.0 N A:GLY391 4.3 12.7 1.0 N A:THR390 4.3 14.5 1.0 OD2 A:ASP733 4.3 16.0 1.0 F4 A:ALF1111 4.3 17.5 1.0 CB A:ASP388 4.5 17.1 1.0 CA A:GLY391 4.5 12.7 1.0 N A:ASP729 4.6 12.9 1.0 F2 A:ALF1111 4.6 17.5 1.0 C A:ASP729 4.7 12.9 1.0 CA A:GLY232 4.7 24.7 1.0 N A:GLY730 4.7 16.4 1.0 OG1 A:THR392 4.7 13.1 1.0 CB A:ASP729 4.8 12.9 1.0 C A:GLY232 4.9 24.7 1.0 N A:THR392 4.9 13.1 1.0 CA A:ASP729 4.9 12.9 1.0 CG2 A:THR390 5.0 14.5 1.0 O A:ASP729 5.0 12.9 1.0 CA A:GLY730 5.0 16.4 1.0

V.C.Young, H.Nakanishi, D.J.Meyer, T.Nishizawa, A.Oshima, P.Artigas, K.Abe. Structure and Function of H + /K + Pump Mutants Reveal Na + /K + Pump Mechanisms. Nat Commun V. 13 5270 2022.
ISSN: ESSN 2041-1723
PubMed: 36085139
DOI: 10.1038/S41467-022-32793-0