Magnesium in PDB 7zf2: Protomeric Substructure From An Octameric Assembly of M. Tuberculosis Rna Polymerase in Complex with Sigma-B Initiation Factor

Enzymatic activity of Protomeric Substructure From An Octameric Assembly of M. Tuberculosis Rna Polymerase in Complex with Sigma-B Initiation Factor

All present enzymatic activity of Protomeric Substructure From An Octameric Assembly of M. Tuberculosis Rna Polymerase in Complex with Sigma-B Initiation Factor:
2.7.7.6;

Other elements in 7zf2:

The structure of Protomeric Substructure From An Octameric Assembly of M. Tuberculosis Rna Polymerase in Complex with Sigma-B Initiation Factor also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Protomeric Substructure From An Octameric Assembly of M. Tuberculosis Rna Polymerase in Complex with Sigma-B Initiation Factor (pdb code 7zf2). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Protomeric Substructure From An Octameric Assembly of M. Tuberculosis Rna Polymerase in Complex with Sigma-B Initiation Factor, PDB code: 7zf2:

Magnesium binding site 1 out of 1 in 7zf2

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Magnesium Binding Sites List in 7zf2

Magnesium binding site 1 out of 1 in the Protomeric Substructure From An Octameric Assembly of M. Tuberculosis Rna Polymerase in Complex with Sigma-B Initiation Factor

Mono view

Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Protomeric Substructure From An Octameric Assembly of M. Tuberculosis Rna Polymerase in Complex with Sigma-B Initiation Factor within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
D:Mg1403 b:43.9 occ:1.00	OD1	D:ASP539	3.1	47.1	1.0
	OD1	D:ASP535	3.2	51.4	1.0
	OD2	D:ASP539	3.2	47.1	1.0
	OD2	D:ASP537	3.4	54.3	1.0
	CG	D:ASP539	3.5	47.1	1.0
	CB	D:ASP537	3.8	54.3	1.0
	OD2	D:ASP535	3.9	51.4	1.0
	CG	D:ASP535	4.0	51.4	1.0
	CG	D:ASP537	4.0	54.3	1.0
	CA	D:ASP537	4.9	54.3	1.0
	N	D:ASP537	4.9	54.3	1.0

Reference:

Z.Morichaud, S.Trapani, R.K.Vishwakarma, L.Chaloin, C.Lionne, J.Lai-Kee-Him, P.Bron, K.Brodolin. Structural Basis of the Mycobacterial Stress-Response Rna Polymerase Auto-Inhibition Via Oligomerization Nat Commun V. 14 484 2023.
ISSN: ESSN 2041-1723
DOI: 10.1038/S41467-023-36113-Y

Page generated: Thu Oct 3 16:45:58 2024

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