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Atomistry » Magnesium » PDB 8av3-8b24 » 8azr | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 8av3-8b24 » 8azr » |
Magnesium in PDB 8azr: Kras in Complex with Precursor 1Enzymatic activity of Kras in Complex with Precursor 1
All present enzymatic activity of Kras in Complex with Precursor 1:
3.6.5.2; Protein crystallography data
The structure of Kras in Complex with Precursor 1, PDB code: 8azr
was solved by
J.Boettcher,
L.Herdeis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Kras in Complex with Precursor 1
(pdb code 8azr). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Kras in Complex with Precursor 1, PDB code: 8azr: Magnesium binding site 1 out of 1 in 8azrGo back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Kras in Complex with Precursor 1
![]() Mono view ![]() Stereo pair view
Reference:
D.Kim,
L.Herdeis,
D.Rudolph,
Y.Zhao,
J.Bottcher,
A.Vides,
C.I.Ayala-Santos,
Y.Pourfarjam,
A.Cuevas-Navarro,
J.Y.Xue,
A.Mantoulidis,
J.Broker,
T.Wunberg,
O.Schaaf,
J.Popow,
B.Wolkerstorfer,
K.G.Kropatsch,
R.Qu,
E.De Stanchina,
B.Sang,
C.Li,
D.B.Mcconnell,
N.Kraut,
P.Lito.
Pan-Kras Inhibitor Disables Oncogenic Signalling and Tumour Growth. Nature 2023.
Page generated: Thu Oct 3 19:06:28 2024
ISSN: ESSN 1476-4687 PubMed: 37258666 DOI: 10.1038/S41586-023-06123-3 |
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