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Atomistry » Magnesium » PDB 8bi7-8bw1 » 8bpy » |
Magnesium in PDB 8bpy: X-Ray Structure of PDE9A in Complex with Inhibitor 13AEnzymatic activity of X-Ray Structure of PDE9A in Complex with Inhibitor 13A
All present enzymatic activity of X-Ray Structure of PDE9A in Complex with Inhibitor 13A:
3.1.4.35; Protein crystallography data
The structure of X-Ray Structure of PDE9A in Complex with Inhibitor 13A, PDB code: 8bpy
was solved by
H.Steuber,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8bpy:
The structure of X-Ray Structure of PDE9A in Complex with Inhibitor 13A also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the X-Ray Structure of PDE9A in Complex with Inhibitor 13A
(pdb code 8bpy). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the X-Ray Structure of PDE9A in Complex with Inhibitor 13A, PDB code: 8bpy: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 8bpyGo back to Magnesium Binding Sites List in 8bpy
Magnesium binding site 1 out
of 2 in the X-Ray Structure of PDE9A in Complex with Inhibitor 13A
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 8bpyGo back to Magnesium Binding Sites List in 8bpy
Magnesium binding site 2 out
of 2 in the X-Ray Structure of PDE9A in Complex with Inhibitor 13A
Mono view Stereo pair view
Reference:
D.Meibom,
S.Micus,
A.L.Andreevski,
S.Anlauf,
P.Bogner,
C.J.Von Buehler,
A.P.Dieskau,
J.Dreher,
F.Eitner,
D.Fliegner,
M.Follmann,
K.M.Gericke,
S.Maassen,
J.Meyer,
K.H.Schlemmer,
H.Steuber,
A.Tersteegen,
F.Wunder.
Bay-7081: A Potent, Selective, and Orally Bioavailable Cyanopyridone-Based PDE9A Inhibitor. J.Med.Chem. V. 65 16420 2022.
Page generated: Thu Oct 3 19:51:02 2024
ISSN: ISSN 0022-2623 PubMed: 36475653 DOI: 10.1021/ACS.JMEDCHEM.2C01267 |
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