Magnesium in PDB 8c4v: Hantaan Virus Polymerase in Replication Elongation State

All present enzymatic activity of Hantaan Virus Polymerase in Replication Elongation State:
2.7.7.48;

The binding sites of Magnesium atom in the Hantaan Virus Polymerase in Replication Elongation State (pdb code 8c4v). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Hantaan Virus Polymerase in Replication Elongation State, PDB code: 8c4v:

Magnesium binding site 1 out of 1 in the Hantaan Virus Polymerase in Replication Elongation State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Hantaan Virus Polymerase in Replication Elongation State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2201 b:14.8 occ:1.00 OD1 A:ASP1099 1.9 16.3 1.0 OE1 A:GLU1170 2.8 20.8 1.0 CG A:ASP1099 3.0 29.0 1.0 O A:ALA971 3.3 18.7 1.0 OD2 A:ASP1099 3.5 30.9 1.0 O A:SER970 3.6 12.7 1.0 O A:GLU1170 3.8 23.1 1.0 C A:ALA971 3.9 7.2 1.0 CD A:GLU1170 4.0 23.4 1.0 C A:SER970 4.0 13.0 1.0 CG A:ASP972 4.2 22.8 1.0 CB A:ASP972 4.2 19.8 1.0 OD1 A:ASP972 4.3 27.4 1.0 CB A:ASP1099 4.3 18.4 1.0 N A:ASP972 4.3 4.5 1.0 CA A:ASP972 4.4 5.5 1.0 OE2 A:GLU1170 4.5 26.4 1.0 CA A:ASP1099 4.5 21.2 1.0 O A:LYS1161 4.5 21.3 1.0 CB A:SER970 4.5 15.9 1.0 N A:ALA971 4.5 10.1 1.0 O A:ALA1100 4.6 17.1 1.0 N A:ALA1100 4.7 15.3 1.0 C A:GLU1170 4.7 19.4 1.0 CA A:SER970 4.7 10.5 1.0 OD2 A:ASP972 4.7 14.9 1.0 CA A:ALA971 4.9 3.5 1.0

Q.Durieux Trouilleton, S.Barata-Garcia, B.Arragain, J.Reguera, H.Malet. Structures of Active Hantaan Virus Polymerase Uncover the Mechanisms of Hantaviridae Genome Replication. Nat Commun V. 14 2954 2023.
ISSN: ESSN 2041-1723
PubMed: 37221161
DOI: 10.1038/S41467-023-38555-W