Magnesium in PDB 8cwi: Fab Arm of Antibody 10G4 Bound to Cov-2 Receptor Binding Domain (Rbd)

The structure of Fab Arm of Antibody 10G4 Bound to Cov-2 Receptor Binding Domain (Rbd), PDB code: 8cwi was solved by D.B.Langley, D.Christ, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.56 / 1.87
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	53.691, 88.639, 81.398, 90, 95.03, 90
R / Rfree (%)	17 / 20.5

The structure of Fab Arm of Antibody 10G4 Bound to Cov-2 Receptor Binding Domain (Rbd) also contains other interesting chemical elements:

Chlorine

(Cl)

3 atoms

The binding sites of Magnesium atom in the Fab Arm of Antibody 10G4 Bound to Cov-2 Receptor Binding Domain (Rbd) (pdb code 8cwi). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Fab Arm of Antibody 10G4 Bound to Cov-2 Receptor Binding Domain (Rbd), PDB code: 8cwi:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Fab Arm of Antibody 10G4 Bound to Cov-2 Receptor Binding Domain (Rbd)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Fab Arm of Antibody 10G4 Bound to Cov-2 Receptor Binding Domain (Rbd) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg601 b:40.7 occ:1.00 O A:HOH885 2.0 38.4 1.0 O A:HOH778 2.1 36.9 1.0 O A:HOH925 2.2 43.5 1.0 O A:HOH926 2.2 33.6 1.0 O A:HOH705 2.2 30.6 1.0 O A:HIS519 4.1 29.6 1.0 O A:LEU518 4.4 42.4 1.0 O A:HOH902 4.4 25.3 1.0 CB A:ALA520 4.6 28.4 1.0 C A:HIS519 4.6 29.7 1.0 O A:HOH835 4.7 45.0 1.0 CB A:HIS519 4.9 36.5 1.0 N A:ALA520 4.9 26.2 1.0

Magnesium binding site 2 out of 2 in the Fab Arm of Antibody 10G4 Bound to Cov-2 Receptor Binding Domain (Rbd)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Fab Arm of Antibody 10G4 Bound to Cov-2 Receptor Binding Domain (Rbd) within 5.0Å range: probe atom residue distance (Å) B Occ L:Mg301 b:41.7 occ:1.00 O L:HOH455 2.0 34.8 1.0 O L:HOH588 2.2 39.8 1.0 O L:HOH579 2.2 44.6 1.0 O H:HOH496 2.2 33.9 1.0 O H:HOH607 2.3 33.6 1.0 O H:HOH615 2.3 35.2 1.0 O L:HOH433 4.0 25.4 1.0 O L:HOH565 4.3 48.6 1.0 O L:PHE98 4.3 27.9 1.0 O H:HOH542 4.4 35.2 1.0 O H:LEU45 4.5 24.2 1.0 O L:HOH582 4.6 48.5 1.0 O L:GLY99 4.9 23.0 1.0 CA L:GLN100 4.9 32.2 1.0 CG H:GLU46 4.9 38.9 1.0 CL H:CL301 4.9 27.7 1.0 O L:HOH479 4.9 36.2 1.0

D.B.Langley, D.Christ. Neutralization of Cov-2 Omicron Lineages By Affinity-Matured Class 5 Antibodies To Be Published.