Atomistry » Magnesium » PDB 8d9r-8diq » 8dbk
Atomistry »
  Magnesium »
    PDB 8d9r-8diq »
      8dbk »

Magnesium in PDB 8dbk: Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops

Enzymatic activity of Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops

All present enzymatic activity of Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops:
2.7.6.1;

Magnesium Binding Sites:

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 12;

Binding sites:

The binding sites of Magnesium atom in the Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops (pdb code 8dbk). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 12 binding sites of Magnesium where determined in the Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops, PDB code: 8dbk:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Magnesium binding site 1 out of 12 in 8dbk

Go back to Magnesium Binding Sites List in 8dbk
Magnesium binding site 1 out of 12 in the Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg404

b:20.7
occ:1.00
O A:HOH501 1.9 20.0 1.0
O1A A:ATP401 2.0 29.8 1.0
O A:HOH502 2.1 19.7 1.0
NE2 A:HIS130 2.1 18.4 1.0
O1B A:ATP401 2.2 33.6 1.0
O1G A:ATP401 2.6 33.3 1.0
CD2 A:HIS130 3.0 18.4 1.0
CE1 A:HIS130 3.1 18.4 1.0
PA A:ATP401 3.1 31.5 1.0
PB A:ATP401 3.2 35.6 1.0
O3A A:ATP401 3.3 26.3 1.0
PG A:ATP401 3.7 52.1 1.0
O3B A:ATP401 3.7 32.1 1.0
O5' A:ATP401 4.2 35.2 1.0
ND1 A:HIS130 4.2 18.4 1.0
CG A:HIS130 4.2 18.4 1.0
OD1 A:ASP98 4.2 20.0 1.0
O2A A:ATP401 4.3 36.2 1.0
CE A:LYS99 4.3 21.3 1.0
C5' A:ATP401 4.3 29.7 1.0
NZ A:LYS99 4.3 21.3 1.0
OD2 A:ASP98 4.4 20.0 1.0
O3G A:ATP401 4.4 38.7 1.0
O2B A:ATP401 4.6 36.8 1.0
CG A:ASP98 4.7 20.0 1.0
O A:ARG96 4.8 22.1 0.2
O2G A:ATP401 4.9 42.0 1.0

Magnesium binding site 2 out of 12 in 8dbk

Go back to Magnesium Binding Sites List in 8dbk
Magnesium binding site 2 out of 12 in the Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg405

b:28.3
occ:1.00
OD2 A:ASP171 2.2 33.7 1.0
O3 A:HSX402 2.7 28.6 1.0
O1 A:HSX402 3.1 33.1 1.0
O2 A:HSX402 3.1 31.1 1.0
CG A:ASP171 3.3 33.7 1.0
OD1 A:ASP171 3.7 33.7 1.0
C3 A:HSX402 3.7 26.7 1.0
C2 A:HSX402 3.8 27.3 1.0
C1 A:HSX402 4.0 25.1 1.0
O2G A:ATP401 4.2 42.0 1.0
OD1 A:ASP220 4.3 26.5 1.0
O1G A:ATP401 4.3 33.3 1.0
O2A A:ATP401 4.3 36.2 1.0
OD2 A:ASP220 4.4 26.5 1.0
OD1 A:ASP221 4.4 24.7 1.0
CE1 A:HIS130 4.5 18.4 1.0
CB A:ASP171 4.6 33.7 1.0
C4 A:HSX402 4.7 25.2 1.0
O4 A:HSX402 4.7 31.5 1.0
CG A:ASP220 4.8 26.5 1.0
PG A:ATP401 4.9 52.1 1.0
CA A:GLY173 5.0 33.4 1.0
C A:GLY173 5.0 33.4 1.0

Magnesium binding site 3 out of 12 in 8dbk

Go back to Magnesium Binding Sites List in 8dbk
Magnesium binding site 3 out of 12 in the Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mg404

b:21.0
occ:1.00
O B:HOH502 1.9 18.6 1.0
O B:HOH501 2.0 19.1 1.0
O3B B:PRP401 2.2 56.0 1.0
NE2 B:HIS130 2.2 16.8 1.0
O1A B:PRP401 2.3 50.0 1.0
O1P B:AMP402 2.5 20.0 1.0
CE1 B:HIS130 3.0 16.8 1.0
CD2 B:HIS130 3.3 16.8 1.0
PB B:PRP401 3.4 60.1 1.0
PA B:PRP401 3.5 50.3 1.0
O3A B:PRP401 3.6 49.5 1.0
P B:AMP402 3.7 20.0 1.0
C5' B:AMP402 3.8 20.0 1.0
O5' B:AMP402 3.9 20.0 1.0
O1B B:PRP401 4.1 53.3 1.0
ND1 B:HIS130 4.2 16.8 1.0
O3P B:AMP402 4.3 20.0 1.0
CG B:HIS130 4.4 16.8 1.0
OD1 B:ASP98 4.4 20.0 1.0
O1 B:PRP401 4.5 53.6 1.0
O2A B:PRP401 4.6 51.4 1.0
O2B B:PRP401 4.6 50.9 1.0
O B:ARG96 4.6 17.0 0.2
OD2 B:ASP98 4.8 20.0 1.0
C1 B:PRP401 4.9 50.3 1.0
CG B:ASP98 5.0 20.0 1.0

Magnesium binding site 4 out of 12 in 8dbk

Go back to Magnesium Binding Sites List in 8dbk
Magnesium binding site 4 out of 12 in the Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mg405

b:25.1
occ:1.00
O1B B:PRP401 1.8 53.3 1.0
O2 B:PRP401 1.8 52.1 1.0
OD2 B:ASP171 2.3 27.8 1.0
OD1 B:ASP171 2.5 27.8 1.0
CG B:ASP171 2.7 27.8 1.0
PB B:PRP401 3.1 60.1 1.0
C2 B:PRP401 3.2 49.1 1.0
O1 B:PRP401 3.3 53.6 1.0
O3 B:PRP401 3.5 52.8 1.0
O3A B:PRP401 3.7 49.5 1.0
OD1 B:ASP220 3.7 23.2 1.0
C1 B:PRP401 3.8 50.3 1.0
O2B B:PRP401 3.8 50.9 1.0
OD1 B:ASP221 3.8 21.3 1.0
C3 B:PRP401 3.9 51.3 1.0
CB B:ASP171 4.1 27.8 1.0
OD2 B:ASP220 4.1 23.2 1.0
PA B:PRP401 4.2 50.3 1.0
CE1 B:HIS130 4.2 16.8 1.0
N B:GLY174 4.3 26.8 1.0
O3B B:PRP401 4.3 56.0 1.0
CA B:GLY173 4.3 26.8 1.0
CG B:ASP220 4.3 23.2 1.0
C B:GLY173 4.5 26.8 1.0
N B:GLY173 4.5 26.8 1.0
NZ B:LYS194 4.7 34.0 1.0
CG B:ASP221 4.7 21.3 1.0
ND1 B:HIS130 4.7 16.8 1.0
O1A B:PRP401 4.8 50.0 1.0
C4 B:PRP401 4.9 47.9 1.0
O4 B:PRP401 5.0 54.8 1.0

Magnesium binding site 5 out of 12 in 8dbk

Go back to Magnesium Binding Sites List in 8dbk
Magnesium binding site 5 out of 12 in the Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Mg404

b:19.4
occ:1.00
O C:HOH502 1.9 18.3 1.0
O C:HOH501 2.0 18.7 1.0
O1A C:ATP401 2.1 29.8 1.0
O1B C:ATP401 2.2 33.6 1.0
NE2 C:HIS130 2.2 16.9 1.0
O1G C:ATP401 2.7 33.3 1.0
CD2 C:HIS130 3.1 16.9 1.0
PB C:ATP401 3.2 35.6 1.0
CE1 C:HIS130 3.2 16.9 1.0
PA C:ATP401 3.2 31.5 1.0
O3A C:ATP401 3.4 26.3 1.0
PG C:ATP401 3.7 52.1 1.0
O3B C:ATP401 3.8 32.1 1.0
NZ C:LYS99 4.0 16.8 1.0
OD1 C:ASP98 4.1 15.5 1.0
O5' C:ATP401 4.2 35.2 1.0
OD2 C:ASP98 4.2 15.5 1.0
CE C:LYS99 4.3 16.8 1.0
C5' C:ATP401 4.3 29.7 1.0
CG C:HIS130 4.3 16.9 1.0
ND1 C:HIS130 4.3 16.9 1.0
O2A C:ATP401 4.4 36.2 1.0
O3G C:ATP401 4.5 38.7 1.0
O2B C:ATP401 4.6 36.8 1.0
CG C:ASP98 4.6 15.5 1.0
O C:ARG96 4.7 17.2 0.2

Magnesium binding site 6 out of 12 in 8dbk

Go back to Magnesium Binding Sites List in 8dbk
Magnesium binding site 6 out of 12 in the Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 6 of Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Mg405

b:27.9
occ:1.00
OD2 C:ASP171 2.0 34.9 1.0
O3 C:HSX402 2.3 28.6 1.0
O1 C:HSX402 2.8 33.1 1.0
O2 C:HSX402 2.8 31.1 1.0
CG C:ASP171 3.0 34.9 1.0
OD1 C:ASP171 3.3 34.9 1.0
C3 C:HSX402 3.3 26.7 1.0
C2 C:HSX402 3.4 27.3 1.0
C1 C:HSX402 3.6 25.1 1.0
OD1 C:ASP220 3.9 25.8 1.0
OD2 C:ASP220 4.0 25.8 1.0
OD1 C:ASP221 4.2 22.9 1.0
C4 C:HSX402 4.3 25.2 1.0
O2A C:ATP401 4.3 36.2 1.0
O4 C:HSX402 4.4 31.5 1.0
CB C:ASP171 4.4 34.9 1.0
CE1 C:HIS130 4.4 16.9 1.0
CG C:ASP220 4.4 25.8 1.0
O1G C:ATP401 4.4 33.3 1.0
O2G C:ATP401 4.6 42.0 1.0

Magnesium binding site 7 out of 12 in 8dbk

Go back to Magnesium Binding Sites List in 8dbk
Magnesium binding site 7 out of 12 in the Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 7 of Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Mg404

b:19.4
occ:1.00
O D:HOH502 1.9 18.3 1.0
O D:HOH501 2.0 18.7 1.0
O1A D:ATP401 2.1 29.8 1.0
O1B D:ATP401 2.2 33.6 1.0
NE2 D:HIS130 2.2 16.9 1.0
O1G D:ATP401 2.7 33.3 1.0
CD2 D:HIS130 3.1 16.9 1.0
PB D:ATP401 3.2 35.6 1.0
CE1 D:HIS130 3.2 16.9 1.0
PA D:ATP401 3.2 31.5 1.0
O3A D:ATP401 3.4 26.3 1.0
PG D:ATP401 3.7 52.1 1.0
O3B D:ATP401 3.8 32.1 1.0
NZ D:LYS99 4.0 16.8 1.0
OD1 D:ASP98 4.1 15.5 1.0
O5' D:ATP401 4.2 35.2 1.0
OD2 D:ASP98 4.2 15.5 1.0
CE D:LYS99 4.3 16.8 1.0
C5' D:ATP401 4.3 29.7 1.0
CG D:HIS130 4.3 16.9 1.0
ND1 D:HIS130 4.3 16.9 1.0
O2A D:ATP401 4.4 36.2 1.0
O3G D:ATP401 4.5 38.7 1.0
O2B D:ATP401 4.6 36.8 1.0
CG D:ASP98 4.6 15.5 1.0
O D:ARG96 4.7 17.2 0.2

Magnesium binding site 8 out of 12 in 8dbk

Go back to Magnesium Binding Sites List in 8dbk
Magnesium binding site 8 out of 12 in the Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 8 of Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Mg405

b:27.9
occ:1.00
OD2 D:ASP171 2.0 34.9 1.0
O3 D:HSX402 2.3 28.6 1.0
O1 D:HSX402 2.8 33.1 1.0
O2 D:HSX402 2.8 31.1 1.0
CG D:ASP171 3.0 34.9 1.0
OD1 D:ASP171 3.3 34.9 1.0
C3 D:HSX402 3.3 26.7 1.0
C2 D:HSX402 3.4 27.3 1.0
C1 D:HSX402 3.6 25.1 1.0
OD1 D:ASP220 3.9 25.8 1.0
OD2 D:ASP220 4.0 25.8 1.0
OD1 D:ASP221 4.2 22.9 1.0
C4 D:HSX402 4.3 25.2 1.0
O2A D:ATP401 4.3 36.2 1.0
O4 D:HSX402 4.4 31.5 1.0
CB D:ASP171 4.4 34.9 1.0
CE1 D:HIS130 4.4 16.9 1.0
CG D:ASP220 4.4 25.8 1.0
O1G D:ATP401 4.4 33.3 1.0
O2G D:ATP401 4.6 42.0 1.0

Magnesium binding site 9 out of 12 in 8dbk

Go back to Magnesium Binding Sites List in 8dbk
Magnesium binding site 9 out of 12 in the Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 9 of Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Mg404

b:19.4
occ:1.00
O E:HOH502 1.9 18.3 1.0
O E:HOH501 2.0 18.7 1.0
O1A E:ATP401 2.1 29.8 1.0
O1B E:ATP401 2.2 33.6 1.0
NE2 E:HIS130 2.2 16.9 1.0
O1G E:ATP401 2.7 33.3 1.0
CD2 E:HIS130 3.1 16.9 1.0
PB E:ATP401 3.2 35.6 1.0
CE1 E:HIS130 3.2 16.9 1.0
PA E:ATP401 3.2 31.5 1.0
O3A E:ATP401 3.4 26.3 1.0
PG E:ATP401 3.7 52.1 1.0
O3B E:ATP401 3.8 32.1 1.0
NZ E:LYS99 4.0 16.8 1.0
OD1 E:ASP98 4.1 15.5 1.0
O5' E:ATP401 4.2 35.2 1.0
OD2 E:ASP98 4.2 15.5 1.0
CE E:LYS99 4.3 16.8 1.0
C5' E:ATP401 4.3 29.7 1.0
CG E:HIS130 4.3 16.9 1.0
ND1 E:HIS130 4.3 16.9 1.0
O2A E:ATP401 4.4 36.2 1.0
O3G E:ATP401 4.5 38.7 1.0
O2B E:ATP401 4.6 36.8 1.0
CG E:ASP98 4.6 15.5 1.0
O E:ARG96 4.7 17.2 0.2

Magnesium binding site 10 out of 12 in 8dbk

Go back to Magnesium Binding Sites List in 8dbk
Magnesium binding site 10 out of 12 in the Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 10 of Human PRPS1 with Phosphate, Atp, and R5P; Hexamer with Resolved Catalytic Loops within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Mg405

b:27.9
occ:1.00
OD2 E:ASP171 2.0 34.9 1.0
O3 E:HSX402 2.3 28.6 1.0
O1 E:HSX402 2.8 33.1 1.0
O2 E:HSX402 2.8 31.1 1.0
CG E:ASP171 3.0 34.9 1.0
OD1 E:ASP171 3.3 34.9 1.0
C3 E:HSX402 3.3 26.7 1.0
C2 E:HSX402 3.4 27.3 1.0
C1 E:HSX402 3.6 25.1 1.0
OD1 E:ASP220 3.9 25.8 1.0
OD2 E:ASP220 4.0 25.8 1.0
OD1 E:ASP221 4.2 22.9 1.0
C4 E:HSX402 4.3 25.2 1.0
O2A E:ATP401 4.3 36.2 1.0
O4 E:HSX402 4.4 31.5 1.0
CB E:ASP171 4.4 34.9 1.0
CE1 E:HIS130 4.4 16.9 1.0
CG E:ASP220 4.4 25.8 1.0
O1G E:ATP401 4.4 33.3 1.0
O2G E:ATP401 4.6 42.0 1.0

Reference:

K.L.Hvorecny, J.M.Kollman. Human PRPS1 Filaments Stabilize Allosteric Sites to Regulate Activity Nat.Struct.Mol.Biol. 2023.
ISSN: ESSN 1545-9985
DOI: 10.1038/S41594-023-00921-Z
Page generated: Fri Oct 4 00:27:43 2024

Last articles

Na in 7Q78
Na in 7Q77
Na in 7Q76
Na in 7Q6Q
Na in 7Q75
Na in 7Q5F
Na in 7Q47
Na in 7Q3Z
Na in 7Q5E
Na in 7Q36
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy