Magnesium in PDB 8ejm: Crystal Structure of Human Deah-Box Helicase DHX15 in Complex with SUGP1 G-Patch

Enzymatic activity of Crystal Structure of Human Deah-Box Helicase DHX15 in Complex with SUGP1 G-Patch

All present enzymatic activity of Crystal Structure of Human Deah-Box Helicase DHX15 in Complex with SUGP1 G-Patch:
3.6.4.13;

Protein crystallography data

The structure of Crystal Structure of Human Deah-Box Helicase DHX15 in Complex with SUGP1 G-Patch, PDB code: 8ejm was solved by J.Huang, L.Tong, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 58.67 / 1.80
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 82.3, 90.956, 213.187, 90, 90, 90
R / Rfree (%) 18.9 / 22.4

Other elements in 8ejm:

The structure of Crystal Structure of Human Deah-Box Helicase DHX15 in Complex with SUGP1 G-Patch also contains other interesting chemical elements:

Chlorine (Cl) 2 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Crystal Structure of Human Deah-Box Helicase DHX15 in Complex with SUGP1 G-Patch (pdb code 8ejm). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Human Deah-Box Helicase DHX15 in Complex with SUGP1 G-Patch, PDB code: 8ejm:

Magnesium binding site 1 out of 1 in 8ejm

Go back to Magnesium Binding Sites List in 8ejm
Magnesium binding site 1 out of 1 in the Crystal Structure of Human Deah-Box Helicase DHX15 in Complex with SUGP1 G-Patch


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human Deah-Box Helicase DHX15 in Complex with SUGP1 G-Patch within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg804

b:29.5
occ:1.00
 O A:HOH936 2.1 32.7 1.0
O A:HOH923 2.1 31.9 1.0
O A:HOH952 2.1 29.0 1.0
O2B A:ADP801 2.1 31.9 1.0
OG1 A:THR167 2.1 27.1 1.0
O A:HOH1010 2.2 33.0 1.0
CB A:THR167 3.1 27.2 1.0
PB A:ADP801 3.3 31.9 1.0
O3B A:ADP801 3.6 29.2 1.0
O A:SER427 3.9 34.5 1.0
OE2 A:GLU261 3.9 31.2 1.0
OD2 A:ASP260 4.0 37.8 1.0
N A:THR167 4.0 30.5 1.0
O2A A:ADP801 4.0 35.3 1.0
CG2 A:THR167 4.1 26.4 1.0
CA A:THR167 4.2 33.4 1.0
O3A A:ADP801 4.3 34.8 1.0
O1B A:ADP801 4.4 32.8 1.0
OD1 A:ASP260 4.4 30.4 1.0
CD A:GLU261 4.5 36.1 1.0
C A:SER427 4.5 36.3 1.0
CG A:ASP260 4.6 31.1 1.0
O A:THR426 4.6 32.9 1.0
O A:HOH1050 4.7 32.6 1.0
PA A:ADP801 4.7 35.1 1.0
NZ A:LYS166 4.7 29.0 1.0
O A:HOH930 4.8 45.5 1.0
CG A:GLU261 4.8 35.1 1.0
CA A:SER427 4.9 33.4 1.0
OE1 A:GLN192 4.9 36.8 1.0
CB A:LYS166 5.0 30.8 1.0

Reference:

J.Zhang, J.Huang, K.Xu, P.Xing, Y.Huang, Z.Liu, L.Tong, J.L.Manley. DHX15 Is Involved in SUGP1-Mediated Rna Missplicing By Mutant SF3B1 in Cancer. Proc.Natl.Acad.Sci.Usa V. 119 12119 2022.
ISSN: ESSN 1091-6490
PubMed: 36459648
DOI: 10.1073/PNAS.2216712119
Page generated: Fri Apr 7 09:27:13 2023

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