Magnesium in PDB 8eok: Structure of the C3BB Proconvertase in Complex with Lufaxin and Factor Xa

All present enzymatic activity of Structure of the C3BB Proconvertase in Complex with Lufaxin and Factor Xa:
3.4.21.47;

The binding sites of Magnesium atom in the Structure of the C3BB Proconvertase in Complex with Lufaxin and Factor Xa (pdb code 8eok). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structure of the C3BB Proconvertase in Complex with Lufaxin and Factor Xa, PDB code: 8eok:

Magnesium binding site 1 out of 1 in the Structure of the C3BB Proconvertase in Complex with Lufaxin and Factor Xa


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of the C3BB Proconvertase in Complex with Lufaxin and Factor Xa within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg801 b:108.6 occ:1.00 OXT H:ASN1641 2.1 129.3 1.0 OG1 D:THR328 2.8 89.7 1.0 OG D:SER253 3.1 104.3 1.0 C H:ASN1641 3.1 129.3 1.0 O H:ASN1641 3.4 129.3 1.0 CB D:SER253 3.5 104.3 1.0 CB D:THR328 4.0 89.7 1.0 OD1 D:ASP254 4.4 118.7 1.0 CG2 D:THR328 4.4 89.7 1.0 CA H:ASN1641 4.5 129.3 1.0 O D:GLY327 4.7 96.3 1.0 CA D:SER253 4.9 104.3 1.0

J.F.Andersen, H.Lei, E.C.Strayer, T.Kanai, V.Pham, X.Z.Pan, P.H.Alvarenga, G.F.Gerber, O.A.Asojo, I.M.B.Francischetti, R.A.Brodsky, J.G.Valenzuela, J.M.C.Ribeiro. A Bispecific Inhibitor of Complement and Coagulation Blocks Activation in Complementopathy Models Via A Novel Mechanism. Blood V. 141 3109 2023.
ISSN: ESSN 1528-0020
PubMed: 36947859
DOI: 10.1182/BLOOD.2022019359