Magnesium in PDB 8fz4: The Von Willebrand Factor A Domain of Anthrax Toxin Receptor 2

The structure of The Von Willebrand Factor A Domain of Anthrax Toxin Receptor 2, PDB code: 8fz4 was solved by M.J.Pedroza-Romo, S.Soleimani, A.Lewis, T.Smith, S.Brown, T.Doukov, J.D.Moody, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.08 / 2.19
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	78.244, 88.969, 59.779, 90, 128.13, 90
R / Rfree (%)	21.8 / 25.6

The structure of The Von Willebrand Factor A Domain of Anthrax Toxin Receptor 2 also contains other interesting chemical elements:

Chlorine

(Cl)

2 atoms

The binding sites of Magnesium atom in the The Von Willebrand Factor A Domain of Anthrax Toxin Receptor 2 (pdb code 8fz4). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the The Von Willebrand Factor A Domain of Anthrax Toxin Receptor 2, PDB code: 8fz4:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the The Von Willebrand Factor A Domain of Anthrax Toxin Receptor 2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of The Von Willebrand Factor A Domain of Anthrax Toxin Receptor 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg301 b:49.3 occ:1.00 O A:HOH414 2.0 39.6 1.0 OG A:SER52 2.3 46.9 1.0 OG A:SER54 2.3 45.2 1.0 OG1 A:THR118 2.7 44.3 1.0 OD2 A:ASP50 3.1 49.7 1.0 OD1 A:ASP148 3.1 47.8 1.0 CG2 A:THR118 3.2 42.4 1.0 CB A:SER52 3.4 38.7 1.0 CB A:THR118 3.5 43.6 1.0 OD2 A:ASP148 3.5 43.5 1.0 CB A:SER54 3.6 46.8 1.0 CG A:ASP148 3.7 48.5 1.0 CL A:CL302 3.7 63.0 1.0 OD1 A:ASP50 3.8 38.4 1.0 CG A:ASP50 3.9 44.6 1.0 O A:LYS150 4.3 45.3 1.0 N A:SER54 4.5 46.9 1.0 CA A:SER54 4.5 47.2 1.0 CG1 A:VAL55 4.6 43.6 1.0 CA A:SER52 4.7 46.1 1.0 CA A:THR118 4.7 43.6 1.0 OG1 A:THR147 4.9 40.8 1.0 N A:VAL55 4.9 45.3 1.0 C A:SER54 4.9 46.5 1.0 CB A:LYS150 5.0 47.8 1.0

Magnesium binding site 2 out of 2 in the The Von Willebrand Factor A Domain of Anthrax Toxin Receptor 2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of The Von Willebrand Factor A Domain of Anthrax Toxin Receptor 2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg301 b:46.3 occ:1.00 OG B:SER54 2.1 45.8 1.0 OG1 B:THR118 2.1 46.8 1.0 OG B:SER52 2.4 45.2 1.0 CL B:CL302 2.5 65.9 1.0 CB B:SER54 3.0 48.5 1.0 CB B:SER52 3.2 44.7 1.0 CB B:THR118 3.3 41.3 1.0 CG2 B:THR118 3.5 39.8 1.0 OD1 B:ASP148 4.0 45.5 1.0 N B:SER54 4.0 48.2 1.0 OD2 B:ASP148 4.0 42.4 1.0 CA B:SER54 4.1 48.9 1.0 OD2 B:ASP50 4.1 43.6 1.0 O B:LYS150 4.1 48.1 1.0 CA B:THR118 4.4 41.6 1.0 CG B:ASP148 4.4 44.2 1.0 OD1 B:ASP50 4.5 43.0 1.0 CA B:SER52 4.5 45.2 1.0 N B:THR118 4.7 43.3 1.0 C B:SER52 4.7 47.2 1.0 CG B:ASP50 4.7 43.0 1.0 N B:GLY53 4.9 48.5 1.0 C B:SER54 4.9 48.1 1.0 O B:HOH447 4.9 41.7 1.0 CB B:LYS150 4.9 47.2 1.0 C B:GLU117 4.9 48.5 1.0

P.L.Gajjar, M.J.Pedroza-Romo, C.Litchfield, M.Callahan, N.Redd, S.Nawarathnage, E.Wilson, J.Averett, S.Soleimani, A.Lewis, T.Smith, S.Brown, T.Doukov, A.Lebedev, J.D.Moody. Decreasing the Flexibility of the Telsam-Target Protein Linker and Omitting the Cleavable Fusion Tag Improves Crystal Order and Diffraction Limits To Be Published.