Magnesium in PDB 8g7m: Atp-Bound MTHSP60 V72I Focus
Enzymatic activity of Atp-Bound MTHSP60 V72I Focus
All present enzymatic activity of Atp-Bound MTHSP60 V72I Focus:
5.6.1.7;
Other elements in 8g7m:
The structure of Atp-Bound MTHSP60 V72I Focus also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Atp-Bound MTHSP60 V72I Focus
(pdb code 8g7m). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 7 binding sites of Magnesium where determined in the
Atp-Bound MTHSP60 V72I Focus, PDB code: 8g7m:
Jump to Magnesium binding site number:
1;
2;
3;
4;
5;
6;
7;
Magnesium binding site 1 out
of 7 in 8g7m
Go back to
Magnesium Binding Sites List in 8g7m
Magnesium binding site 1 out
of 7 in the Atp-Bound MTHSP60 V72I Focus
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Atp-Bound MTHSP60 V72I Focus within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg602
b:43.6
occ:1.00
|
O2G
|
A:ATP601
|
2.1
|
41.5
|
1.0
|
OD1
|
A:ASP85
|
2.2
|
46.6
|
1.0
|
O1A
|
A:ATP601
|
3.0
|
41.5
|
1.0
|
CG
|
A:ASP85
|
3.0
|
46.6
|
1.0
|
O3B
|
A:ATP601
|
3.1
|
41.5
|
1.0
|
O1B
|
A:ATP601
|
3.1
|
41.5
|
1.0
|
OD2
|
A:ASP85
|
3.1
|
46.6
|
1.0
|
PG
|
A:ATP601
|
3.2
|
41.5
|
1.0
|
PB
|
A:ATP601
|
3.4
|
41.5
|
1.0
|
O3A
|
A:ATP601
|
3.7
|
41.5
|
1.0
|
PA
|
A:ATP601
|
3.9
|
41.5
|
1.0
|
O3G
|
A:ATP601
|
4.1
|
41.5
|
1.0
|
O1G
|
A:ATP601
|
4.3
|
41.5
|
1.0
|
O
|
A:SER149
|
4.3
|
54.5
|
1.0
|
N
|
A:GLY86
|
4.4
|
44.4
|
1.0
|
CB
|
A:ASP85
|
4.5
|
46.6
|
1.0
|
OD2
|
A:ASP397
|
4.5
|
55.2
|
1.0
|
CB
|
A:ASP397
|
4.6
|
55.2
|
1.0
|
CG
|
A:ASP397
|
4.7
|
55.2
|
1.0
|
O5'
|
A:ATP601
|
4.9
|
41.5
|
1.0
|
CA
|
A:ASP85
|
4.9
|
46.6
|
1.0
|
O2B
|
A:ATP601
|
4.9
|
41.5
|
1.0
|
|
Magnesium binding site 2 out
of 7 in 8g7m
Go back to
Magnesium Binding Sites List in 8g7m
Magnesium binding site 2 out
of 7 in the Atp-Bound MTHSP60 V72I Focus
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Atp-Bound MTHSP60 V72I Focus within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Mg602
b:38.1
occ:1.00
|
O2G
|
B:ATP601
|
2.4
|
40.8
|
1.0
|
OD1
|
B:ASP85
|
2.7
|
45.0
|
1.0
|
O1A
|
B:ATP601
|
2.7
|
40.8
|
1.0
|
O1B
|
B:ATP601
|
2.9
|
40.8
|
1.0
|
O3B
|
B:ATP601
|
3.2
|
40.8
|
1.0
|
PB
|
B:ATP601
|
3.3
|
40.8
|
1.0
|
O3A
|
B:ATP601
|
3.4
|
40.8
|
1.0
|
PG
|
B:ATP601
|
3.4
|
40.8
|
1.0
|
CG
|
B:ASP85
|
3.5
|
45.0
|
1.0
|
OD2
|
B:ASP85
|
3.5
|
45.0
|
1.0
|
PA
|
B:ATP601
|
3.6
|
40.8
|
1.0
|
O
|
B:SER149
|
4.2
|
52.3
|
1.0
|
O1G
|
B:ATP601
|
4.4
|
40.8
|
1.0
|
O5'
|
B:ATP601
|
4.5
|
40.8
|
1.0
|
O3G
|
B:ATP601
|
4.5
|
40.8
|
1.0
|
OD2
|
B:ASP397
|
4.5
|
53.2
|
1.0
|
C5'
|
B:ATP601
|
4.7
|
40.8
|
1.0
|
N
|
B:GLY86
|
4.8
|
42.5
|
1.0
|
CB
|
B:ASP397
|
4.8
|
53.2
|
1.0
|
CG
|
B:ASP397
|
4.9
|
53.2
|
1.0
|
O2A
|
B:ATP601
|
4.9
|
40.8
|
1.0
|
O2B
|
B:ATP601
|
4.9
|
40.8
|
1.0
|
CB
|
B:ASP85
|
4.9
|
45.0
|
1.0
|
CA
|
B:SER149
|
5.0
|
52.3
|
1.0
|
|
Magnesium binding site 3 out
of 7 in 8g7m
Go back to
Magnesium Binding Sites List in 8g7m
Magnesium binding site 3 out
of 7 in the Atp-Bound MTHSP60 V72I Focus
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 3 of Atp-Bound MTHSP60 V72I Focus within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Mg602
b:35.6
occ:1.00
|
OD1
|
C:ASP85
|
2.6
|
44.3
|
1.0
|
O2G
|
C:ATP601
|
2.8
|
42.5
|
1.0
|
O1B
|
C:ATP601
|
2.9
|
42.5
|
1.0
|
O1A
|
C:ATP601
|
2.9
|
42.5
|
1.0
|
OD2
|
C:ASP85
|
3.1
|
44.3
|
1.0
|
CG
|
C:ASP85
|
3.2
|
44.3
|
1.0
|
O3B
|
C:ATP601
|
3.5
|
42.5
|
1.0
|
PB
|
C:ATP601
|
3.5
|
42.5
|
1.0
|
O3A
|
C:ATP601
|
3.6
|
42.5
|
1.0
|
PA
|
C:ATP601
|
3.8
|
42.5
|
1.0
|
PG
|
C:ATP601
|
3.8
|
42.5
|
1.0
|
O
|
C:SER149
|
4.2
|
53.7
|
1.0
|
O5'
|
C:ATP601
|
4.6
|
42.5
|
1.0
|
CB
|
C:ASP85
|
4.7
|
44.3
|
1.0
|
N
|
C:GLY86
|
4.7
|
43.4
|
1.0
|
O3G
|
C:ATP601
|
4.8
|
42.5
|
1.0
|
C5'
|
C:ATP601
|
4.8
|
42.5
|
1.0
|
OD2
|
C:ASP397
|
4.8
|
54.0
|
1.0
|
CA
|
C:SER149
|
4.8
|
53.7
|
1.0
|
CB
|
C:ASP397
|
4.9
|
54.0
|
1.0
|
O1G
|
C:ATP601
|
4.9
|
42.5
|
1.0
|
C
|
C:SER149
|
4.9
|
53.7
|
1.0
|
CG
|
C:ASP397
|
5.0
|
54.0
|
1.0
|
|
Magnesium binding site 4 out
of 7 in 8g7m
Go back to
Magnesium Binding Sites List in 8g7m
Magnesium binding site 4 out
of 7 in the Atp-Bound MTHSP60 V72I Focus
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 4 of Atp-Bound MTHSP60 V72I Focus within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Mg602
b:44.0
occ:1.00
|
OD1
|
D:ASP85
|
2.1
|
49.1
|
1.0
|
OD2
|
D:ASP85
|
2.6
|
49.1
|
1.0
|
CG
|
D:ASP85
|
2.7
|
49.1
|
1.0
|
O2G
|
D:ATP601
|
2.7
|
55.7
|
1.0
|
O1B
|
D:ATP601
|
3.0
|
55.7
|
1.0
|
O3B
|
D:ATP601
|
3.3
|
55.7
|
1.0
|
O1A
|
D:ATP601
|
3.5
|
55.7
|
1.0
|
PB
|
D:ATP601
|
3.5
|
55.7
|
1.0
|
PG
|
D:ATP601
|
3.6
|
55.7
|
1.0
|
O3A
|
D:ATP601
|
3.8
|
55.7
|
1.0
|
CB
|
D:ASP85
|
4.1
|
49.1
|
1.0
|
PA
|
D:ATP601
|
4.2
|
55.7
|
1.0
|
O
|
D:SER149
|
4.3
|
52.2
|
1.0
|
N
|
D:GLY86
|
4.3
|
48.2
|
1.0
|
O3G
|
D:ATP601
|
4.5
|
55.7
|
1.0
|
CB
|
D:ASP397
|
4.7
|
53.3
|
1.0
|
O5'
|
D:ATP601
|
4.7
|
55.7
|
1.0
|
O1G
|
D:ATP601
|
4.7
|
55.7
|
1.0
|
OD2
|
D:ASP397
|
4.7
|
53.3
|
1.0
|
CA
|
D:ASP85
|
4.8
|
49.1
|
1.0
|
CA
|
D:SER149
|
4.8
|
52.2
|
1.0
|
CG
|
D:ASP397
|
4.9
|
53.3
|
1.0
|
CB
|
D:SER149
|
5.0
|
52.2
|
1.0
|
|
Magnesium binding site 5 out
of 7 in 8g7m
Go back to
Magnesium Binding Sites List in 8g7m
Magnesium binding site 5 out
of 7 in the Atp-Bound MTHSP60 V72I Focus
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 5 of Atp-Bound MTHSP60 V72I Focus within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Mg602
b:38.0
occ:1.00
|
O2G
|
E:ATP601
|
2.1
|
43.6
|
1.0
|
O1A
|
E:ATP601
|
2.1
|
43.6
|
1.0
|
OD1
|
E:ASP85
|
2.8
|
45.1
|
1.0
|
O1B
|
E:ATP601
|
3.0
|
43.6
|
1.0
|
O3B
|
E:ATP601
|
3.1
|
43.6
|
1.0
|
PG
|
E:ATP601
|
3.2
|
43.6
|
1.0
|
PA
|
E:ATP601
|
3.2
|
43.6
|
1.0
|
O3A
|
E:ATP601
|
3.3
|
43.6
|
1.0
|
PB
|
E:ATP601
|
3.3
|
43.6
|
1.0
|
CG
|
E:ASP85
|
3.6
|
45.1
|
1.0
|
OD2
|
E:ASP85
|
3.6
|
45.1
|
1.0
|
O3G
|
E:ATP601
|
4.1
|
43.6
|
1.0
|
O5'
|
E:ATP601
|
4.3
|
43.6
|
1.0
|
O1G
|
E:ATP601
|
4.3
|
43.6
|
1.0
|
O2A
|
E:ATP601
|
4.3
|
43.6
|
1.0
|
O
|
E:SER149
|
4.4
|
52.0
|
1.0
|
C5'
|
E:ATP601
|
4.6
|
43.6
|
1.0
|
N
|
E:GLY86
|
4.7
|
41.9
|
1.0
|
O2B
|
E:ATP601
|
4.8
|
43.6
|
1.0
|
OD2
|
E:ASP397
|
5.0
|
57.1
|
1.0
|
|
Magnesium binding site 6 out
of 7 in 8g7m
Go back to
Magnesium Binding Sites List in 8g7m
Magnesium binding site 6 out
of 7 in the Atp-Bound MTHSP60 V72I Focus
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 6 of Atp-Bound MTHSP60 V72I Focus within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Mg602
b:41.9
occ:1.00
|
OD1
|
F:ASP85
|
2.1
|
48.4
|
1.0
|
OD2
|
F:ASP85
|
2.5
|
48.4
|
1.0
|
CG
|
F:ASP85
|
2.6
|
48.4
|
1.0
|
O1B
|
F:ATP601
|
2.9
|
45.3
|
1.0
|
O2G
|
F:ATP601
|
3.1
|
45.3
|
1.0
|
O1A
|
F:ATP601
|
3.2
|
45.3
|
1.0
|
O3B
|
F:ATP601
|
3.5
|
45.3
|
1.0
|
PB
|
F:ATP601
|
3.6
|
45.3
|
1.0
|
O3A
|
F:ATP601
|
3.9
|
45.3
|
1.0
|
PG
|
F:ATP601
|
4.0
|
45.3
|
1.0
|
CB
|
F:ASP85
|
4.1
|
48.4
|
1.0
|
PA
|
F:ATP601
|
4.1
|
45.3
|
1.0
|
O
|
F:SER149
|
4.3
|
53.9
|
1.0
|
N
|
F:GLY86
|
4.4
|
44.5
|
1.0
|
CA
|
F:SER149
|
4.7
|
53.9
|
1.0
|
O3G
|
F:ATP601
|
4.7
|
45.3
|
1.0
|
CB
|
F:SER149
|
4.8
|
53.9
|
1.0
|
CA
|
F:ASP85
|
4.8
|
48.4
|
1.0
|
O5'
|
F:ATP601
|
4.9
|
45.3
|
1.0
|
CB
|
F:ASP397
|
4.9
|
55.2
|
1.0
|
C
|
F:SER149
|
5.0
|
53.9
|
1.0
|
|
Magnesium binding site 7 out
of 7 in 8g7m
Go back to
Magnesium Binding Sites List in 8g7m
Magnesium binding site 7 out
of 7 in the Atp-Bound MTHSP60 V72I Focus
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 7 of Atp-Bound MTHSP60 V72I Focus within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Mg602
b:39.7
occ:1.00
|
OD1
|
G:ASP85
|
2.2
|
46.8
|
1.0
|
O2G
|
G:ATP601
|
2.3
|
44.3
|
1.0
|
O1B
|
G:ATP601
|
2.6
|
44.3
|
1.0
|
O1A
|
G:ATP601
|
2.9
|
44.3
|
1.0
|
O3B
|
G:ATP601
|
3.0
|
44.3
|
1.0
|
CG
|
G:ASP85
|
3.0
|
46.8
|
1.0
|
PB
|
G:ATP601
|
3.1
|
44.3
|
1.0
|
OD2
|
G:ASP85
|
3.2
|
46.8
|
1.0
|
PG
|
G:ATP601
|
3.3
|
44.3
|
1.0
|
O3A
|
G:ATP601
|
3.3
|
44.3
|
1.0
|
PA
|
G:ATP601
|
3.7
|
44.3
|
1.0
|
O3G
|
G:ATP601
|
4.2
|
44.3
|
1.0
|
N
|
G:GLY86
|
4.3
|
43.3
|
1.0
|
O1G
|
G:ATP601
|
4.4
|
44.3
|
1.0
|
CB
|
G:ASP85
|
4.5
|
46.8
|
1.0
|
O
|
G:SER149
|
4.5
|
54.3
|
1.0
|
O5'
|
G:ATP601
|
4.5
|
44.3
|
1.0
|
O2B
|
G:ATP601
|
4.6
|
44.3
|
1.0
|
C5'
|
G:ATP601
|
4.8
|
44.3
|
1.0
|
OD2
|
G:ASP397
|
4.8
|
58.4
|
1.0
|
CB
|
G:ASP397
|
4.9
|
58.4
|
1.0
|
CA
|
G:ASP85
|
4.9
|
46.8
|
1.0
|
O2A
|
G:ATP601
|
4.9
|
44.3
|
1.0
|
|
Reference:
J.R.Braxton,
H.Shao,
E.Tse,
J.E.Gestwicki,
D.R.Southworth.
Asymmetric Apical Domain States of Mitochondrial HSP60 Coordinate Substrate Engagement and Chaperonin Assembly. Biorxiv 2023.
ISSN: ISSN 2692-8205
PubMed: 37293102
DOI: 10.1101/2023.05.15.540872
Page generated: Fri Oct 4 03:02:22 2024
|