|
Atomistry » Magnesium » PDB 8jh8-8jvf » 8jjs | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 8jh8-8jvf » 8jjs » |
Magnesium in PDB 8jjs: Human K-Ras G12D (Gdp-Bound) in Complex with Cyclic Peptide Inhibitor AP10343Protein crystallography data
The structure of Human K-Ras G12D (Gdp-Bound) in Complex with Cyclic Peptide Inhibitor AP10343, PDB code: 8jjs
was solved by
M.Irie,
T.A.Fukami,
M.Tanada,
A.Ohta,
T.Torizawa,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8jjs:
The structure of Human K-Ras G12D (Gdp-Bound) in Complex with Cyclic Peptide Inhibitor AP10343 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Human K-Ras G12D (Gdp-Bound) in Complex with Cyclic Peptide Inhibitor AP10343
(pdb code 8jjs). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human K-Ras G12D (Gdp-Bound) in Complex with Cyclic Peptide Inhibitor AP10343, PDB code: 8jjs: Magnesium binding site 1 out of 1 in 8jjsGo back to Magnesium Binding Sites List in 8jjs
Magnesium binding site 1 out
of 1 in the Human K-Ras G12D (Gdp-Bound) in Complex with Cyclic Peptide Inhibitor AP10343
Mono view Stereo pair view
Reference:
M.Tanada,
M.Tamiya,
A.Matsuo,
A.Chiyoda,
K.Takano,
T.Ito,
M.Irie,
T.Kotake,
R.Takeyama,
H.Kawada,
R.Hayashi,
S.Ishikawa,
K.Nomura,
N.Furuichi,
Y.Morita,
M.Kage,
S.Hashimoto,
K.Nii,
H.Sase,
K.Ohara,
A.Ohta,
S.Kuramoto,
Y.Nishimura,
H.Iikura,
T.Shiraishi.
Development of Orally Bioavailable Peptides Targeting An Intracellular Protein: From A Hit to A Clinical Kras Inhibitor J.Am.Chem.Soc. 2023.
Page generated: Fri Oct 4 13:11:03 2024
ISSN: ESSN 1520-5126 DOI: 10.1021/JACS.3C03886 |
Last articlesZn in 9JPJZn in 9JP7 Zn in 9JPK Zn in 9JPL Zn in 9GN6 Zn in 9GN7 Zn in 9GKU Zn in 9GKW Zn in 9GKX Zn in 9GL0 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |