Magnesium in PDB 8jpb: Cryo-Em Structure of NTSR1-GRK2-Galpha(Q) Complexes 1

All present enzymatic activity of Cryo-Em Structure of NTSR1-GRK2-Galpha(Q) Complexes 1:
2.7.11.15;

The structure of Cryo-Em Structure of NTSR1-GRK2-Galpha(Q) Complexes 1 also contains other interesting chemical elements:

Aluminium	(Al)	1 atom
Fluorine	(F)	5 atoms

The binding sites of Magnesium atom in the Cryo-Em Structure of NTSR1-GRK2-Galpha(Q) Complexes 1 (pdb code 8jpb). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Cryo-Em Structure of NTSR1-GRK2-Galpha(Q) Complexes 1, PDB code: 8jpb:

Magnesium binding site 1 out of 1 in the Cryo-Em Structure of NTSR1-GRK2-Galpha(Q) Complexes 1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of NTSR1-GRK2-Galpha(Q) Complexes 1 within 5.0Å range: probe atom residue distance (Å) B Occ Q:Mg402 b:87.4 occ:1.00 O3B Q:GDP401 1.9 99.5 1.0 OG Q:SER53 1.9 91.8 1.0 F3 Q:ALF403 2.3 96.7 1.0 OG1 Q:THR186 2.6 89.8 1.0 CB Q:THR186 2.8 89.8 1.0 CB Q:SER53 3.0 91.8 1.0 PB Q:GDP401 3.4 99.5 1.0 CG2 Q:THR186 3.8 89.8 1.0 AL Q:ALF403 3.8 96.7 1.0 N Q:THR186 3.8 89.8 1.0 CA Q:THR186 3.9 89.8 1.0 OD1 Q:ASP205 3.9 85.9 1.0 N Q:SER53 3.9 91.8 1.0 F1 Q:ALF403 3.9 96.7 1.0 O2B Q:GDP401 4.0 99.5 1.0 O2A Q:GDP401 4.0 99.5 1.0 CA Q:SER53 4.0 91.8 1.0 O1B Q:GDP401 4.2 99.5 1.0 O3A Q:GDP401 4.2 99.5 1.0 O1A Q:GDP401 4.3 99.5 1.0 PA Q:GDP401 4.4 99.5 1.0 F2 Q:ALF403 4.4 96.7 1.0 O Q:VAL184 4.4 101.1 1.0 CG Q:ASP205 4.6 85.9 1.0 OD2 Q:ASP205 4.6 85.9 1.0 C Q:THR186 4.8 89.8 1.0 O Q:THR186 4.9 89.8 1.0 O Q:VAL206 4.9 80.0 1.0 C Q:PRO185 5.0 95.8 1.0

J.Duan, H.Liu, F.Zhao, Q.Yuan, Y.Ji, X.Cai, X.He, X.Li, J.Li, K.Wu, T.Gao, S.Zhu, S.Lin, M.W.Wang, X.Cheng, W.Yin, Y.Jiang, D.Yang, H.E.Xu. Gpcr Activation and GRK2 Assembly By A Biased Intracellular Agonist. Nature 2023.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-023-06395-9