Magnesium in PDB 8ox8: Cryo-Em Structure of ATP8B1-CDC50A in E2P Autoinhibited "Open" Conformation

All present enzymatic activity of Cryo-Em Structure of ATP8B1-CDC50A in E2P Autoinhibited "Open" Conformation:
7.6.2.1;

The binding sites of Magnesium atom in the Cryo-Em Structure of ATP8B1-CDC50A in E2P Autoinhibited "Open" Conformation (pdb code 8ox8). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Cryo-Em Structure of ATP8B1-CDC50A in E2P Autoinhibited "Open" Conformation, PDB code: 8ox8:

Magnesium binding site 1 out of 1 in the Cryo-Em Structure of ATP8B1-CDC50A in E2P Autoinhibited "Open" Conformation


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of ATP8B1-CDC50A in E2P Autoinhibited "Open" Conformation within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1301 b:44.1 occ:1.00 OD2 A:PHD454 1.9 48.2 1.0 O A:THR456 2.3 51.4 1.0 OP3 A:PHD454 2.5 48.2 1.0 OD1 A:ASP893 2.5 50.5 1.0 CG A:PHD454 3.1 48.2 1.0 O A:ASP893 3.1 50.5 1.0 C A:THR456 3.5 51.4 1.0 OD2 A:ASP897 3.5 49.7 1.0 CG A:ASP893 3.6 50.5 1.0 P A:PHD454 3.6 48.2 1.0 OD1 A:PHD454 3.8 48.2 1.0 C A:ASP893 4.0 50.5 1.0 OD2 A:ASP893 4.1 50.5 1.0 O A:ALA229 4.1 58.6 1.0 CB A:PHD454 4.2 48.2 1.0 CB A:THR456 4.2 51.4 1.0 CA A:THR456 4.3 51.4 1.0 OP2 A:PHD454 4.3 48.2 1.0 N A:ASP893 4.3 50.5 1.0 N A:THR456 4.4 51.4 1.0 OD1 A:ASN896 4.5 52.3 1.0 N A:GLY457 4.5 49.5 1.0 CA A:ASP893 4.6 50.5 1.0 OG1 A:THR458 4.6 47.2 1.0 CB A:ASP893 4.7 50.5 1.0 CG A:ASP897 4.7 49.7 1.0 CA A:GLY457 4.7 49.5 1.0 OP1 A:PHD454 4.8 48.2 1.0 ND2 A:ASN896 4.9 52.3 1.0 N A:GLY894 4.9 53.0 1.0 N A:LYS455 4.9 51.0 1.0 CG2 A:THR456 5.0 51.4 1.0 N A:THR458 5.0 47.2 1.0

T.Dieudonne, F.Kummerer, M.J.Laursen, C.Stock, R.K.Flygaard, S.Khalid, G.Lenoir, J.A.Lyons, K.Lindorff-Larsen, P.Nissen. Activation and Substrate Specificity of the Human P4-Atpase ATP8B1. Nat Commun V. 14 7492 2023.
ISSN: ESSN 2041-1723
PubMed: 37980352
DOI: 10.1038/S41467-023-42828-9