Magnesium in PDB 8p7b: Cryoem Structure of METTL6 Trna Serrs Complex in A 1:2:2 Stoichiometry
Enzymatic activity of Cryoem Structure of METTL6 Trna Serrs Complex in A 1:2:2 Stoichiometry
All present enzymatic activity of Cryoem Structure of METTL6 Trna Serrs Complex in A 1:2:2 Stoichiometry:
6.1.1.11;
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Cryoem Structure of METTL6 Trna Serrs Complex in A 1:2:2 Stoichiometry
(pdb code 8p7b). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 6 binding sites of Magnesium where determined in the
Cryoem Structure of METTL6 Trna Serrs Complex in A 1:2:2 Stoichiometry, PDB code: 8p7b:
Jump to Magnesium binding site number:
1;
2;
3;
4;
5;
6;
Magnesium binding site 1 out
of 6 in 8p7b
Go back to
Magnesium Binding Sites List in 8p7b
Magnesium binding site 1 out
of 6 in the Cryoem Structure of METTL6 Trna Serrs Complex in A 1:2:2 Stoichiometry
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Cryoem Structure of METTL6 Trna Serrs Complex in A 1:2:2 Stoichiometry within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
T:Mg101
b:76.7
occ:1.00
|
OP2
|
T:G9
|
2.0
|
77.7
|
1.0
|
OP2
|
T:4AC12
|
2.7
|
77.6
|
1.0
|
OP1
|
T:4AC12
|
2.9
|
77.6
|
1.0
|
P
|
T:4AC12
|
3.2
|
77.6
|
1.0
|
P
|
T:G9
|
3.3
|
77.7
|
1.0
|
OP1
|
T:G9
|
3.7
|
77.7
|
1.0
|
O3'
|
T:C11
|
4.0
|
77.1
|
1.0
|
O5'
|
T:G9
|
4.0
|
77.7
|
1.0
|
C3'
|
T:C11
|
4.3
|
77.1
|
1.0
|
O5'
|
T:C11
|
4.3
|
77.1
|
1.0
|
OP2
|
T:C11
|
4.4
|
77.1
|
1.0
|
OP1
|
T:U8
|
4.4
|
78.0
|
1.0
|
O3'
|
T:U8
|
4.5
|
78.0
|
1.0
|
O5'
|
T:4AC12
|
4.6
|
77.6
|
1.0
|
O6
|
T:G13
|
4.6
|
77.6
|
1.0
|
C3'
|
T:U8
|
4.7
|
78.0
|
1.0
|
C5
|
T:4AC12
|
4.7
|
77.6
|
1.0
|
C6
|
T:4AC12
|
4.7
|
77.6
|
1.0
|
P
|
T:C11
|
4.8
|
77.1
|
1.0
|
N7
|
T:G13
|
4.9
|
77.6
|
1.0
|
OP1
|
T:C11
|
5.0
|
77.1
|
1.0
|
|
Magnesium binding site 2 out
of 6 in 8p7b
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Magnesium Binding Sites List in 8p7b
Magnesium binding site 2 out
of 6 in the Cryoem Structure of METTL6 Trna Serrs Complex in A 1:2:2 Stoichiometry
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Cryoem Structure of METTL6 Trna Serrs Complex in A 1:2:2 Stoichiometry within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
T:Mg102
b:76.5
occ:1.00
|
OP2
|
T:A22
|
3.8
|
81.0
|
1.0
|
CM7
|
T:4AC12
|
4.0
|
77.6
|
1.0
|
N7
|
T:G23
|
4.1
|
81.5
|
1.0
|
O6
|
T:G24
|
4.1
|
81.0
|
1.0
|
N7
|
T:G24
|
4.3
|
81.0
|
1.0
|
O6
|
T:G23
|
4.6
|
81.5
|
1.0
|
C8
|
T:G23
|
4.9
|
81.5
|
1.0
|
C6
|
T:G24
|
4.9
|
81.0
|
1.0
|
C5
|
T:G23
|
4.9
|
81.5
|
1.0
|
P
|
T:A22
|
5.0
|
81.0
|
1.0
|
|
Magnesium binding site 3 out
of 6 in 8p7b
Go back to
Magnesium Binding Sites List in 8p7b
Magnesium binding site 3 out
of 6 in the Cryoem Structure of METTL6 Trna Serrs Complex in A 1:2:2 Stoichiometry
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 3 of Cryoem Structure of METTL6 Trna Serrs Complex in A 1:2:2 Stoichiometry within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
T:Mg103
b:83.9
occ:1.00
|
OP1
|
T:5MC48
|
2.1
|
78.9
|
1.0
|
OP2
|
T:U50
|
2.9
|
85.3
|
1.0
|
P
|
T:5MC48
|
3.6
|
78.9
|
1.0
|
P
|
T:U50
|
4.1
|
85.3
|
1.0
|
O3'
|
T:G47I
|
4.2
|
69.5
|
1.0
|
O5'
|
T:U50
|
4.3
|
85.3
|
1.0
|
C5'
|
T:5MC48
|
4.4
|
78.9
|
1.0
|
C5
|
T:U50
|
4.4
|
85.3
|
1.0
|
OP2
|
T:5MC48
|
4.4
|
78.9
|
1.0
|
O5'
|
T:5MC48
|
4.5
|
78.9
|
1.0
|
OP1
|
T:G49
|
4.6
|
81.7
|
1.0
|
C6
|
T:U50
|
4.7
|
85.3
|
1.0
|
OP2
|
T:G51
|
4.7
|
91.5
|
1.0
|
C3'
|
T:5MC48
|
4.8
|
78.9
|
1.0
|
N7
|
T:G51
|
4.8
|
91.5
|
1.0
|
O5'
|
T:G49
|
4.9
|
81.7
|
1.0
|
OP1
|
T:U50
|
4.9
|
85.3
|
1.0
|
|
Magnesium binding site 4 out
of 6 in 8p7b
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Magnesium Binding Sites List in 8p7b
Magnesium binding site 4 out
of 6 in the Cryoem Structure of METTL6 Trna Serrs Complex in A 1:2:2 Stoichiometry
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 4 of Cryoem Structure of METTL6 Trna Serrs Complex in A 1:2:2 Stoichiometry within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
R:Mg101
b:75.9
occ:1.00
|
OP2
|
R:4AC12
|
1.8
|
76.2
|
1.0
|
OP2
|
R:G9
|
2.3
|
73.7
|
1.0
|
P
|
R:4AC12
|
3.1
|
76.2
|
1.0
|
P
|
R:G9
|
3.4
|
73.7
|
1.0
|
OP1
|
R:4AC12
|
3.8
|
76.2
|
1.0
|
OP1
|
R:G9
|
3.8
|
73.7
|
1.0
|
O3'
|
R:C11
|
3.9
|
74.7
|
1.0
|
OP1
|
R:U8
|
4.2
|
76.2
|
1.0
|
C3'
|
R:C11
|
4.2
|
74.7
|
1.0
|
O5'
|
R:4AC12
|
4.2
|
76.2
|
1.0
|
O5'
|
R:C11
|
4.2
|
74.7
|
1.0
|
O5'
|
R:G9
|
4.3
|
73.7
|
1.0
|
C5
|
R:4AC12
|
4.4
|
76.2
|
1.0
|
O6
|
R:G13
|
4.5
|
76.2
|
1.0
|
OP2
|
R:C11
|
4.5
|
74.7
|
1.0
|
O3'
|
R:U8
|
4.7
|
76.2
|
1.0
|
P
|
R:C11
|
4.8
|
74.7
|
1.0
|
C3'
|
R:U8
|
4.8
|
76.2
|
1.0
|
N7
|
R:G13
|
4.9
|
76.2
|
1.0
|
OP1
|
R:C11
|
4.9
|
74.7
|
1.0
|
C6
|
R:4AC12
|
5.0
|
76.2
|
1.0
|
|
Magnesium binding site 5 out
of 6 in 8p7b
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Magnesium Binding Sites List in 8p7b
Magnesium binding site 5 out
of 6 in the Cryoem Structure of METTL6 Trna Serrs Complex in A 1:2:2 Stoichiometry
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 5 of Cryoem Structure of METTL6 Trna Serrs Complex in A 1:2:2 Stoichiometry within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
R:Mg102
b:70.7
occ:1.00
|
N7
|
R:G23
|
4.0
|
79.6
|
1.0
|
OP2
|
R:A22
|
4.1
|
78.8
|
1.0
|
O6
|
R:G23
|
4.4
|
79.6
|
1.0
|
N7
|
R:G24
|
4.4
|
78.5
|
1.0
|
O6
|
R:G24
|
4.4
|
78.5
|
1.0
|
OP2
|
R:G23
|
4.6
|
79.6
|
1.0
|
OP1
|
R:A22
|
4.6
|
78.8
|
1.0
|
P
|
R:A22
|
4.7
|
78.8
|
1.0
|
C5
|
R:G23
|
4.8
|
79.6
|
1.0
|
C8
|
R:G23
|
4.9
|
79.6
|
1.0
|
C6
|
R:G23
|
4.9
|
79.6
|
1.0
|
O5'
|
R:A22
|
4.9
|
78.8
|
1.0
|
|
Magnesium binding site 6 out
of 6 in 8p7b
Go back to
Magnesium Binding Sites List in 8p7b
Magnesium binding site 6 out
of 6 in the Cryoem Structure of METTL6 Trna Serrs Complex in A 1:2:2 Stoichiometry
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 6 of Cryoem Structure of METTL6 Trna Serrs Complex in A 1:2:2 Stoichiometry within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
R:Mg103
b:83.1
occ:1.00
|
OP1
|
R:5MC48
|
2.2
|
77.9
|
1.0
|
OP2
|
R:U50
|
3.2
|
85.5
|
1.0
|
P
|
R:5MC48
|
3.6
|
77.9
|
1.0
|
O3'
|
R:G47I
|
4.2
|
64.9
|
1.0
|
P
|
R:U50
|
4.3
|
85.5
|
1.0
|
O5'
|
R:U50
|
4.4
|
85.5
|
1.0
|
C5
|
R:U50
|
4.4
|
85.5
|
1.0
|
OP2
|
R:5MC48
|
4.4
|
77.9
|
1.0
|
OP2
|
R:G51
|
4.6
|
89.9
|
1.0
|
N7
|
R:G51
|
4.6
|
89.9
|
1.0
|
O5'
|
R:5MC48
|
4.6
|
77.9
|
1.0
|
C5'
|
R:5MC48
|
4.6
|
77.9
|
1.0
|
C6
|
R:U50
|
4.7
|
85.5
|
1.0
|
OP1
|
R:G49
|
4.7
|
82.5
|
1.0
|
|
Reference:
P.Throll,
L.G.Dolce,
P.R.Lastres,
K.Arnold,
L.Tengo,
S.Basu,
S.Kaiser,
R.Schneider,
E.Kowalinski.
Structural Basis of the Cooperation Between the M3C-Rna-Methyltransferase METTL6 with Serrs Amino-Acyl-Synthetase For Trna Recognition To Be Published.
Page generated: Fri Oct 4 15:56:54 2024
|