Magnesium in PDB 8pqw: Cytoplasmic Dynein-1 Motor Domain Bound to Dynactin-P150GLUED and LIS1

The binding sites of Magnesium atom in the Cytoplasmic Dynein-1 Motor Domain Bound to Dynactin-P150GLUED and LIS1 (pdb code 8pqw). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Cytoplasmic Dynein-1 Motor Domain Bound to Dynactin-P150GLUED and LIS1, PDB code: 8pqw:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Cytoplasmic Dynein-1 Motor Domain Bound to Dynactin-P150GLUED and LIS1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cytoplasmic Dynein-1 Motor Domain Bound to Dynactin-P150GLUED and LIS1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg4802 b:102.5 occ:1.00 O2B A:ADP4801 1.8 95.9 1.0 OD2 A:ASP1958 2.0 113.8 1.0 CG A:ASP1958 2.3 113.8 1.0 OD1 A:ASP1958 2.9 113.8 1.0 CB A:ASP1958 3.1 113.8 1.0 PB A:ADP4801 3.3 95.9 1.0 CG2 A:THR1913 3.5 100.1 1.0 CB A:THR1913 3.9 100.1 1.0 NH2 A:ARG2358 4.0 93.5 1.0 O1B A:ADP4801 4.0 95.9 1.0 O3A A:ADP4801 4.1 95.9 1.0 O3B A:ADP4801 4.3 95.9 1.0 CA A:ASP1958 4.3 113.8 1.0 ND2 A:ASN1931 4.3 116.6 1.0 OG1 A:THR1913 4.4 100.1 1.0 CG2 A:THR2017 4.6 107.6 1.0 OD1 A:ASN1931 4.6 116.6 1.0 OD2 A:ASP2320 4.7 103.4 1.0 CZ A:ARG2358 4.7 93.5 1.0 CG A:ASN1931 4.9 116.6 1.0 NH1 A:ARG2358 4.9 93.5 1.0 O A:ASN2316 4.9 92.1 1.0

Magnesium binding site 2 out of 2 in the Cytoplasmic Dynein-1 Motor Domain Bound to Dynactin-P150GLUED and LIS1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Cytoplasmic Dynein-1 Motor Domain Bound to Dynactin-P150GLUED and LIS1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg4804 b:103.7 occ:1.00 OE2 A:GLU2344 2.2 99.6 1.0 OG A:SER2231 2.3 103.8 1.0 O1G A:ATP4803 2.4 103.8 1.0 OE2 A:GLU2688 2.4 88.4 1.0 OE1 A:GLU2344 2.5 99.6 1.0 CB A:SER2231 2.5 103.8 1.0 CD A:GLU2344 2.7 99.6 1.0 O2A A:ATP4803 3.5 103.8 1.0 CD A:GLU2688 3.6 88.4 1.0 OD2 A:ASP2304 3.7 97.2 1.0 CA A:SER2231 3.8 103.8 1.0 PG A:ATP4803 3.9 103.8 1.0 OE1 A:GLU2688 4.2 88.4 1.0 CG A:GLU2344 4.2 99.6 1.0 O2B A:ATP4803 4.4 103.8 1.0 OD1 A:ASP2304 4.4 97.2 1.0 CG A:ASP2304 4.4 97.2 1.0 N A:SER2231 4.5 103.8 1.0 NH2 A:ARG2729 4.5 93.8 1.0 O3G A:ATP4803 4.6 103.8 1.0 PA A:ATP4803 4.7 103.8 1.0 O2G A:ATP4803 4.7 103.8 1.0 O3B A:ATP4803 4.8 103.8 1.0 CG A:GLU2688 4.8 88.4 1.0 O1A A:ATP4803 4.9 103.8 1.0 C A:SER2231 5.0 103.8 1.0 CE1 A:HIS2689 5.0 88.9 1.0

K.Singh, C.K.Lau, G.Manigrasso, R.Gassmann, A.P.Carter. Molecular Mechanism of Dynein-Dynactin Complex Assembly By LIS1 Science 2024.
ISSN: ESSN 1095-9203
DOI: 10.1126/SCIENCE.ADK8544