Magnesium in PDB 8pqz: Cytoplasmic Dynein-1 A1/A2 Motor Domains Bound to LIS1

The binding sites of Magnesium atom in the Cytoplasmic Dynein-1 A1/A2 Motor Domains Bound to LIS1 (pdb code 8pqz). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Cytoplasmic Dynein-1 A1/A2 Motor Domains Bound to LIS1, PDB code: 8pqz:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Cytoplasmic Dynein-1 A1/A2 Motor Domains Bound to LIS1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cytoplasmic Dynein-1 A1/A2 Motor Domains Bound to LIS1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg4802 b:186.5 occ:1.00 O1B A:ADP4801 2.2 171.2 1.0 CB A:THR1913 2.8 177.8 1.0 PB A:ADP4801 3.4 171.2 1.0 CB A:ASP1958 3.6 214.5 1.0 O3B A:ADP4801 3.6 171.2 1.0 O3A A:ADP4801 4.1 171.2 1.0 CA A:THR1913 4.2 177.8 1.0 CA A:ASP1958 4.3 214.5 1.0 CB A:THR2017 4.4 189.2 1.0 N A:THR1913 4.4 177.8 1.0 O2B A:ADP4801 4.6 171.2 1.0

Magnesium binding site 2 out of 4 in the Cytoplasmic Dynein-1 A1/A2 Motor Domains Bound to LIS1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Cytoplasmic Dynein-1 A1/A2 Motor Domains Bound to LIS1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg4804 b:183.4 occ:1.00 O1G A:ATP4803 2.2 169.4 1.0 CB A:SER2231 2.3 171.3 1.0 O2A A:ATP4803 3.1 169.4 1.0 CA A:SER2231 3.6 171.3 1.0 PG A:ATP4803 3.7 169.4 1.0 PA A:ATP4803 4.1 169.4 1.0 O1A A:ATP4803 4.1 169.4 1.0 N A:SER2231 4.2 171.3 1.0 O2B A:ATP4803 4.3 169.4 1.0 O3A A:ATP4803 4.4 169.4 1.0 O3B A:ATP4803 4.5 169.4 1.0 O3G A:ATP4803 4.5 169.4 1.0 O2G A:ATP4803 4.6 169.4 1.0 PB A:ATP4803 4.8 169.4 1.0 C A:SER2231 4.8 171.3 1.0 CB A:GLU2344 5.0 177.1 1.0

Magnesium binding site 3 out of 4 in the Cytoplasmic Dynein-1 A1/A2 Motor Domains Bound to LIS1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Cytoplasmic Dynein-1 A1/A2 Motor Domains Bound to LIS1 within 5.0Å range: probe atom residue distance (Å) B Occ J:Mg4802 b:228.6 occ:1.00 O2B J:ADP4801 2.0 197.7 1.0 PB J:ADP4801 3.3 197.7 1.0 CB J:THR1913 3.5 180.7 1.0 O3A J:ADP4801 3.8 197.7 1.0 O3B J:ADP4801 3.9 197.7 1.0 CB J:ASP1958 3.9 215.4 1.0 O1B J:ADP4801 4.5 197.7 1.0 CA J:THR1913 4.9 180.7 1.0

Magnesium binding site 4 out of 4 in the Cytoplasmic Dynein-1 A1/A2 Motor Domains Bound to LIS1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Cytoplasmic Dynein-1 A1/A2 Motor Domains Bound to LIS1 within 5.0Å range: probe atom residue distance (Å) B Occ J:Mg4804 b:190.4 occ:1.00 O2B J:ATP4803 2.5 185.0 1.0 O2A J:ATP4803 2.6 185.0 1.0 O1G J:ATP4803 2.8 185.0 1.0 O3B J:ATP4803 2.9 185.0 1.0 CB J:SER2231 2.9 182.9 1.0 O3A J:ATP4803 2.9 185.0 1.0 PB J:ATP4803 3.0 185.0 1.0 PA J:ATP4803 3.3 185.0 1.0 PG J:ATP4803 3.4 185.0 1.0 O1A J:ATP4803 4.0 185.0 1.0 CA J:SER2231 4.2 182.9 1.0 O3G J:ATP4803 4.4 185.0 1.0 O1B J:ATP4803 4.4 185.0 1.0 N J:SER2231 4.5 182.9 1.0 O2G J:ATP4803 4.5 185.0 1.0 O5' J:ATP4803 4.6 185.0 1.0

K.Singh, C.K.Lau, G.Manigrasso, R.Gassmann, A.P.Carter. Molecular Mechanism of Dynein-Dynactin Complex Assembly By LIS1 Science 2024.
ISSN: ESSN 1095-9203
DOI: 10.1126/SCIENCE.ADK8544