Magnesium in PDB 8pr7: Aurora-A in Complex with CEP192 and An Inhibitory Monobody

All present enzymatic activity of Aurora-A in Complex with CEP192 and An Inhibitory Monobody:
2.7.11.1;

The structure of Aurora-A in Complex with CEP192 and An Inhibitory Monobody, PDB code: 8pr7 was solved by J.A.Miles, R.Bayliss, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	64.11 / 2.76
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	112.58, 112.58, 216.31, 90, 90, 90
R / Rfree (%)	20.2 / 25.6

The binding sites of Magnesium atom in the Aurora-A in Complex with CEP192 and An Inhibitory Monobody (pdb code 8pr7). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Aurora-A in Complex with CEP192 and An Inhibitory Monobody, PDB code: 8pr7:

Magnesium binding site 1 out of 1 in the Aurora-A in Complex with CEP192 and An Inhibitory Monobody


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Aurora-A in Complex with CEP192 and An Inhibitory Monobody within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg503 b:86.0 occ:1.00 OD1 E:ASP78 3.1 108.1 1.0 OE1 D:GLU175 3.4 111.9 1.0 OE2 D:GLU175 3.5 103.9 1.0 CD D:GLU175 3.8 121.1 1.0 CD2 E:TYR80 3.9 82.9 1.0 CG E:ASP78 4.1 112.2 1.0 OD2 E:ASP78 4.3 99.0 1.0 O E:HOH102 4.4 97.2 1.0 CE2 E:TYR80 4.4 89.6 1.0 CB E:PHE79 4.8 85.0 1.0

J.A.Miles, R.Bayliss. Aurora-A in Complex with CEP192 and An Inhibitory Monobody To Be Published.