Magnesium in PDB 8q75: Copper-Transporting Atpase HMA4 in E2P State with Alf

The structure of Copper-Transporting Atpase HMA4 in E2P State with Alf also contains other interesting chemical elements:

Fluorine	(F)	4 atoms
Aluminium	(Al)	1 atom

The binding sites of Magnesium atom in the Copper-Transporting Atpase HMA4 in E2P State with Alf (pdb code 8q75). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Copper-Transporting Atpase HMA4 in E2P State with Alf, PDB code: 8q75:

Magnesium binding site 1 out of 1 in the Copper-Transporting Atpase HMA4 in E2P State with Alf


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Copper-Transporting Atpase HMA4 in E2P State with Alf within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1002 b:181.8 occ:1.00 F2 A:ALF1001 1.9 165.2 1.0 OD2 A:ASP641 1.9 150.2 1.0 OD2 A:ASP848 2.0 154.4 1.0 O A:THR643 2.0 164.8 1.0 OD1 A:ASP848 2.1 157.6 1.0 CG A:ASP848 2.3 153.9 1.0 CG A:ASP641 3.1 145.6 1.0 C A:THR643 3.3 159.8 1.0 F3 A:ALF1001 3.4 160.9 1.0 AL A:ALF1001 3.4 165.0 1.0 CB A:ASP848 3.8 150.2 1.0 CB A:ASP641 3.9 138.9 1.0 N A:GLY849 4.0 159.8 1.0 OD2 A:ASP852 4.0 165.7 1.0 OD1 A:ASP641 4.1 148.5 1.0 CA A:GLY644 4.1 154.6 1.0 N A:GLY644 4.1 151.1 1.0 OG1 A:THR645 4.1 152.9 1.0 N A:ASP848 4.2 150.0 1.0 CA A:THR643 4.2 159.4 1.0 F4 A:ALF1001 4.3 165.9 1.0 N A:THR645 4.3 151.2 1.0 CA A:ASP848 4.4 149.3 1.0 CB A:THR643 4.4 159.9 1.0 N A:THR643 4.5 159.7 1.0 C A:ASP848 4.5 153.5 1.0 CA A:GLY849 4.6 160.4 1.0 C A:GLY644 4.7 153.3 1.0 OD1 A:ASP852 4.8 161.4 1.0 CG A:ASP852 4.8 162.9 1.0 O A:GLY481 5.0 166.3 1.0

Z.Guo, F.Oradd, V.Bagenholm, C.Gronberg, J.F.Ma, P.Ott, Y.Wang, M.Andersson, P.A.Pedersen, K.Wang, P.Gourdon. Diverse Roles of the Metal Binding Domains and Transport Mechanism of Copper Transporting P-Type Atpases. Nat Commun V. 15 2690 2024.
ISSN: ESSN 2041-1723
PubMed: 38538615
DOI: 10.1038/S41467-024-47001-4