Magnesium in PDB 8tmb: Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-1

The binding sites of Magnesium atom in the Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-1 (pdb code 8tmb). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 6 binding sites of Magnesium where determined in the Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-1, PDB code: 8tmb:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6;

Magnesium binding site 1 out of 6 in the Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg401 b:42.7 occ:1.00 OD1 B:ASP175 2.5 45.5 1.0 CG B:ASP175 3.2 45.5 1.0 OD2 B:ASP175 3.2 45.5 1.0 CE1 B:HIS257 4.1 43.9 1.0 OE1 C:GLU88 4.2 50.0 1.0 CB B:ASP175 4.6 45.5 1.0 ND1 B:HIS257 4.8 43.9 1.0 OD2 B:ASP179 4.8 49.8 1.0 O C:GLY11 4.8 54.2 1.0 CG C:LYS9 5.0 55.6 1.0 O C:LEU12 5.0 55.4 1.0 CA C:PRO14 5.0 54.3 1.0 CB C:PRO14 5.0 54.3 1.0

Magnesium binding site 2 out of 6 in the Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-1 within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg401 b:28.7 occ:1.00 OD1 C:ASP175 3.6 36.0 1.0 O D:LEU12 3.7 41.8 1.0 OD2 C:ASP175 3.9 36.0 1.0 O D:LYS9 4.1 45.2 1.0 OE1 D:GLU88 4.1 38.6 1.0 CG C:ASP175 4.2 36.0 1.0 CE D:LYS9 4.3 45.2 1.0 OE2 D:GLU88 4.3 38.6 1.0 CD D:GLU88 4.5 38.6 1.0 OD2 C:ASP179 4.6 38.9 1.0 CB D:LYS9 4.6 45.2 1.0 OD1 C:ASP179 4.8 38.9 1.0 NE2 C:HIS257 4.8 33.3 1.0 C D:LEU12 4.8 41.8 1.0

Magnesium binding site 3 out of 6 in the Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-1 within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg402 b:34.1 occ:1.00 OD1 E:ASP89 2.5 34.3 1.0 NE2 E:GLN95 2.6 38.5 1.0 NE2 D:HIS257 2.7 31.5 1.0 OD1 D:ASP253 3.2 32.1 1.0 CD2 D:HIS257 3.3 31.5 1.0 CG E:ASP89 3.7 34.3 1.0 CE1 D:HIS257 3.7 31.5 1.0 CD E:GLN95 3.8 38.5 1.0 OD2 E:ASP89 4.2 34.3 1.0 CG D:ASP253 4.2 32.1 1.0 ND2 E:ASN92 4.2 39.3 1.0 OE2 E:GLU88 4.4 36.2 1.0 CD E:GLU88 4.5 36.2 1.0 OE1 E:GLN95 4.5 38.5 1.0 CG D:HIS257 4.5 31.5 1.0 OD2 D:ASP253 4.6 32.1 1.0 ND1 D:HIS257 4.7 31.5 1.0 CG E:GLN95 4.8 38.5 1.0 CB E:ASP89 4.8 34.3 1.0 CG E:GLU88 4.8 36.2 1.0 OE1 E:GLU88 4.9 36.2 1.0 CA E:ASP89 4.9 34.3 1.0 O D:ASP253 5.0 32.1 1.0

Magnesium binding site 4 out of 6 in the Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-1 within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg403 b:89.4 occ:1.00 O D:GLY312 3.3 81.2 1.0 OD1 C:ASN314 3.7 92.0 1.0 O C:GLY312 3.7 82.7 1.0 ND2 B:ASN314 3.9 93.5 1.0 ND2 C:ASN314 4.1 92.0 1.0 CG C:ASN314 4.1 92.0 1.0 OD1 B:ASN314 4.2 93.5 1.0 OD1 D:ASN314 4.4 88.8 1.0 C D:GLY312 4.5 81.2 1.0 CG B:ASN314 4.5 93.5 1.0 O B:GLY312 4.6 81.9 1.0 C C:GLY312 4.9 82.7 1.0 O A:GLY312 5.0 87.5 1.0 OD1 E:ASN314 5.0 95.6 1.0

Magnesium binding site 5 out of 6 in the Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-1 within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg404 b:103.1 occ:1.00 CA E:GLY309 4.7 70.5 1.0 CA D:GLY309 4.8 70.2 1.0

Magnesium binding site 6 out of 6 in the Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 6 of Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-1 within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg401 b:33.8 occ:1.00 OE2 E:GLU88 2.2 36.2 1.0 CD E:GLU88 3.4 36.2 1.0 OD2 D:ASP175 3.9 31.4 1.0 OE1 E:GLU88 3.9 36.2 1.0 CE1 D:HIS257 4.0 31.5 1.0 CD E:LYS9 4.2 45.5 1.0 OD1 D:ASP175 4.3 31.4 1.0 CA E:PRO14 4.4 40.0 1.0 CG D:ASP175 4.5 31.4 1.0 O E:LEU12 4.5 42.1 1.0 CG E:GLU88 4.6 36.2 1.0 NE2 D:HIS257 4.7 31.5 1.0 CB E:LYS9 4.7 45.5 1.0 N E:PRO14 4.9 40.0 1.0 O E:PRO13 5.0 40.5 1.0 OD1 D:ASP179 5.0 37.1 1.0 CB E:PRO14 5.0 40.0 1.0 ND1 D:HIS257 5.0 31.5 1.0

S.K.Erramilli, K.Nosol, K.Pietrzak-Lichwa, T.Li, P.Dutka, J.Hou, M.Zhao, E.Perozo, A.A.Kossiakoff. Structural Basis For Cora Channel Gating Using Conformation-Specific Synthetic Antibodies To Be Published.