Magnesium in PDB 8tmc: Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-2

The binding sites of Magnesium atom in the Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-2 (pdb code 8tmc). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 6 binding sites of Magnesium where determined in the Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-2, PDB code: 8tmc:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6;

Magnesium binding site 1 out of 6 in the Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg401 b:46.0 occ:1.00 OD2 A:ASP175 3.4 45.2 1.0 OE2 B:GLU88 3.5 59.7 1.0 O B:LEU12 4.0 55.9 1.0 OD2 A:ASP179 4.2 52.5 1.0 CG A:ASP175 4.3 45.2 1.0 CE1 A:HIS257 4.3 46.4 1.0 OD1 A:ASP175 4.4 45.2 1.0 CD B:GLU88 4.5 59.7 1.0 CA B:PRO14 4.6 53.9 1.0 OE1 B:GLU88 4.6 59.7 1.0 OD1 A:ASP179 4.6 52.5 1.0 O B:LYS9 4.6 58.2 1.0 N B:PRO14 4.8 53.9 1.0 CG A:ASP179 4.8 52.5 1.0 O B:PRO13 4.9 54.5 1.0 C B:PRO13 4.9 54.5 1.0

Magnesium binding site 2 out of 6 in the Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg402 b:86.8 occ:1.00 OD1 A:ASN314 2.8 95.5 1.0 ND2 E:ASN314 3.1 96.4 1.0 CG E:ASN314 3.6 96.4 1.0 OD1 E:ASN314 3.6 96.4 1.0 OD1 D:ASN314 3.7 103.2 1.0 CG A:ASN314 3.9 95.5 1.0 MG B:MG401 3.9 70.0 1.0 ND2 C:ASN314 4.3 104.7 1.0 ND2 A:ASN314 4.4 95.5 1.0 O E:GLY312 4.4 94.2 1.0 O A:GLY312 4.5 94.0 1.0 O E:MET313 4.5 94.4 1.0 O D:MET313 4.6 99.9 1.0 CA E:ASN314 4.7 96.4 1.0 CB E:ASN314 4.7 96.4 1.0 C E:MET313 4.8 94.4 1.0 CG D:ASN314 4.8 103.2 1.0 N E:ASN314 4.9 96.4 1.0

Magnesium binding site 3 out of 6 in the Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg401 b:70.0 occ:1.00 O B:GLY312 3.2 94.6 1.0 O C:GLY312 3.8 95.6 1.0 ND2 A:ASN314 3.9 95.5 1.0 MG A:MG402 3.9 86.8 1.0 O A:GLY312 4.2 94.0 1.0 OD1 A:ASN314 4.2 95.5 1.0 C B:GLY312 4.4 94.6 1.0 CA C:GLY312 4.5 95.6 1.0 CG A:ASN314 4.5 95.5 1.0 C C:GLY312 4.5 95.6 1.0 O E:GLY312 4.8 94.2 1.0

Magnesium binding site 4 out of 6 in the Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-2 within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg401 b:31.7 occ:1.00 OD2 C:ASP175 3.3 41.7 1.0 OD1 C:ASP175 3.9 41.7 1.0 CG C:ASP175 4.0 41.7 1.0 OE1 D:GLU88 4.2 45.6 1.0 OD2 C:ASP179 4.2 43.5 1.0 OE2 D:GLU88 4.2 45.6 1.0 O D:LEU12 4.3 44.0 1.0 CA D:PRO14 4.4 43.9 1.0 CE1 C:HIS257 4.5 42.0 1.0 CD D:GLU88 4.6 45.6 1.0 OD1 C:ASP179 4.7 43.5 1.0 O D:LYS9 4.7 47.1 1.0 OD2 C:ASP253 4.7 45.9 1.0 CB D:PRO14 4.8 43.9 1.0 N D:PRO14 4.8 43.9 1.0 CG D:PRO14 4.9 43.9 1.0 CG C:ASP179 4.9 43.5 1.0

Magnesium binding site 5 out of 6 in the Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-2 within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg401 b:41.9 occ:1.00 OD1 D:ASP253 2.5 44.7 1.0 OD1 E:ASP89 2.7 48.4 1.0 NE2 D:HIS257 3.1 42.1 1.0 CG D:ASP253 3.4 44.7 1.0 CG E:ASP89 3.5 48.4 1.0 OE1 E:GLN95 3.6 46.7 1.0 OD2 D:ASP253 3.6 44.7 1.0 CE1 D:HIS257 3.7 42.1 1.0 NE2 E:GLN95 3.8 46.7 1.0 OD2 E:ASP89 3.8 48.4 1.0 CD E:GLN95 4.0 46.7 1.0 CD2 D:HIS257 4.0 42.1 1.0 NZ E:LYS98 4.5 43.9 1.0 ND1 D:HIS257 4.7 42.1 1.0 CB D:ASP253 4.7 44.7 1.0 OD2 D:ASP256 4.7 44.3 1.0 CB E:ASP89 4.8 48.4 1.0 CD E:GLU88 4.8 49.2 1.0 CG D:HIS257 4.9 42.1 1.0 CA E:ASP89 4.9 48.4 1.0 OE1 E:GLU88 4.9 49.2 1.0 N E:ASP89 5.0 48.4 1.0

Magnesium binding site 6 out of 6 in the Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 6 of Cryo-Em Structure of Cora in Complex with Conformation-Specific Synthetic Antibody C12 and 20 Mm MGCL2, State MG20-2 within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg402 b:34.3 occ:1.00 OD2 D:ASP175 3.3 41.5 1.0 OE2 E:GLU88 3.4 49.2 1.0 O E:LEU12 3.6 46.9 1.0 OE1 E:GLU88 4.1 49.2 1.0 CD E:GLU88 4.2 49.2 1.0 CG D:ASP175 4.3 41.5 1.0 CA E:PRO14 4.4 44.3 1.0 OD2 D:ASP179 4.4 42.9 1.0 OD1 D:ASP175 4.6 41.5 1.0 N E:PRO14 4.6 44.3 1.0 CB E:PRO14 4.7 44.3 1.0 C E:LEU12 4.8 46.9 1.0 OD1 D:ASP179 4.8 42.9 1.0 C E:PRO13 4.8 46.1 1.0 O E:PRO13 4.9 46.1 1.0 NE2 D:HIS257 4.9 42.1 1.0 OD2 D:ASP253 5.0 44.7 1.0

S.K.Erramilli, K.Nosol, K.Pietrzak-Lichwa, T.Li, P.Dutka, J.Hou, M.Zhao, E.Perozo, A.A.Kossiakoff. Structural Basis For Cora Channel Gating Using Conformation-Specific Synthetic Antibodies To Be Published.