Magnesium in PDB 8v7j: Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 20 Mm MG2+ For 600S

All present enzymatic activity of Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 20 Mm MG2+ For 600S:
2.7.7.7;

The structure of Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 20 Mm MG2+ For 600S, PDB code: 8v7j was solved by C.Chang, Y.Gao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.92 / 1.66
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	98.722, 98.722, 82.093, 90, 90, 120
R / Rfree (%)	20.1 / 22.4

The binding sites of Magnesium atom in the Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 20 Mm MG2+ For 600S (pdb code 8v7j). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 20 Mm MG2+ For 600S, PDB code: 8v7j:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 20 Mm MG2+ For 600S


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 20 Mm MG2+ For 600S within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg501 b:20.5 occ:0.80 OD1 A:ASP13 1.8 24.9 1.0 O1B A:DTP503 2.0 20.9 0.8 O2G A:DTP503 2.1 24.9 0.8 O A:MET14 2.1 25.2 1.0 OD2 A:ASP115 2.1 35.5 1.0 O1A A:DTP503 2.4 29.5 0.8 CG A:ASP13 2.8 25.9 1.0 PB A:DTP503 3.1 23.1 0.8 OD2 A:ASP13 3.2 45.0 1.0 C A:MET14 3.2 18.3 1.0 PG A:DTP503 3.3 22.4 0.8 CG A:ASP115 3.3 29.3 1.0 O3A A:DTP503 3.4 25.0 0.8 PA A:DTP503 3.5 32.4 0.8 O3B A:DTP503 3.5 20.8 0.8 MG A:MG502 3.6 26.3 0.7 O A:HOH643 3.7 36.8 1.0 N A:MET14 3.8 15.5 1.0 C5' A:DTP503 3.9 27.4 0.8 O3G A:DTP503 3.9 21.9 0.8 OD1 A:ASP115 4.0 34.4 1.0 CA A:MET14 4.0 14.1 1.0 CB A:ASP13 4.1 21.6 1.0 C A:ASP13 4.1 16.3 1.0 N A:ASP15 4.2 16.6 1.0 N A:CYS16 4.2 18.9 1.0 O5' A:DTP503 4.3 32.2 0.8 O A:HOH602 4.4 26.3 0.7 CB A:ASP115 4.4 19.1 1.0 CA A:ASP15 4.4 16.9 1.0 O2B A:DTP503 4.5 21.1 0.8 C A:ASP15 4.5 19.3 1.0 O1G A:DTP503 4.5 24.0 0.8 CA A:ASP13 4.6 15.0 1.0 O A:ASP13 4.6 17.8 1.0 CB A:MET14 4.6 19.4 1.0 O A:ASP115 4.6 24.8 1.0 O2A A:DTP503 4.7 34.3 0.8 N A:PHE17 4.7 15.5 1.0 O A:HOH601 4.8 33.2 0.8 NZ A:LYS231 4.9 39.5 1.0 CB A:PHE17 4.9 14.7 1.0 CA A:CYS16 5.0 16.6 1.0

Magnesium binding site 2 out of 2 in the Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 20 Mm MG2+ For 600S


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 20 Mm MG2+ For 600S within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg502 b:26.3 occ:0.70 O A:HOH601 2.0 33.2 0.8 O A:HOH602 2.1 26.3 0.7 O1A A:DTP503 2.2 29.5 0.8 OD2 A:ASP13 2.2 45.0 1.0 OD1 A:ASP115 2.2 34.4 1.0 CG A:GLU116 2.5 29.6 1.0 C3' P:CAR9 2.6 34.7 0.3 OE2 A:GLU116 2.6 47.6 1.0 O3' P:CAR9 2.8 36.2 0.3 CG A:ASP115 2.8 29.3 1.0 OD2 A:ASP115 2.9 35.5 1.0 CD A:GLU116 2.9 35.7 1.0 CG A:ASP13 3.2 25.9 1.0 PA A:DTP503 3.4 32.4 0.8 C4' P:CAR9 3.5 33.6 0.3 MG A:MG501 3.6 20.5 0.8 OD1 A:ASP13 3.6 24.9 1.0 O3' P:CAR9 3.6 38.2 0.7 O A:HOH643 3.7 36.8 1.0 C2' P:CAR9 3.8 34.3 0.3 O5' A:DTP503 3.8 32.2 0.8 C5' P:CAR9 3.9 33.5 0.3 CB A:GLU116 3.9 25.0 1.0 O2A A:DTP503 4.0 34.3 0.8 C5' A:DTP503 4.0 27.4 0.8 OG A:SER113 4.0 27.4 1.0 OE1 A:GLU116 4.1 35.1 1.0 O A:ASP115 4.2 24.8 1.0 CB A:ASP115 4.3 19.1 1.0 C A:ASP115 4.3 24.4 1.0 O2' P:CAR9 4.4 37.9 0.3 CB A:ASP13 4.4 21.6 1.0 C3' P:CAR9 4.5 37.9 0.7 N A:GLU116 4.6 22.3 1.0 CA A:GLU116 4.6 24.0 1.0 O2G A:DTP503 4.6 24.9 0.8 O3A A:DTP503 4.7 25.0 0.8 O4' P:CAR9 4.7 32.2 0.3 O1B A:DTP503 4.7 20.9 0.8 CA A:ASP115 4.8 16.0 1.0 C1' P:CAR9 4.8 32.0 0.3 NZ A:LYS224 4.9 38.6 1.0 CA A:ASP13 5.0 15.0 1.0

C.Chang, Y.Gao. Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 20 Mm MG2+ For 600S To Be Published.