Magnesium in PDB 8z03: Lactate Bound to Human Gtp-Specific Succinyl-Coa Synthetase

All present enzymatic activity of Lactate Bound to Human Gtp-Specific Succinyl-Coa Synthetase:
6.2.1.4; 6.2.1.5;

The structure of Lactate Bound to Human Gtp-Specific Succinyl-Coa Synthetase, PDB code: 8z03 was solved by R.L.Liu, X.L.Ren, L.T.Li, Y.Zhang, H.Huang, Y.M.Zhao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.13 / 1.99
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	54.12, 134.37, 57.83, 90, 92.13, 90
R / Rfree (%)	20.7 / 24.4

The binding sites of Magnesium atom in the Lactate Bound to Human Gtp-Specific Succinyl-Coa Synthetase (pdb code 8z03). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Lactate Bound to Human Gtp-Specific Succinyl-Coa Synthetase, PDB code: 8z03:

Magnesium binding site 1 out of 1 in the Lactate Bound to Human Gtp-Specific Succinyl-Coa Synthetase


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Lactate Bound to Human Gtp-Specific Succinyl-Coa Synthetase within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg402 b:33.6 occ:0.76 O B:2OP401 2.0 33.5 0.8 C B:2OP401 2.8 30.7 0.8 OXT B:2OP401 3.0 25.8 0.8 O2 A:PO42002 3.0 15.8 1.0 O3 A:PO42002 3.5 21.4 1.0 O A:HOH2105 3.5 32.0 1.0 CA B:GLY272 3.6 17.1 1.0 P A:PO42002 3.8 20.1 1.0 N B:GLY298 4.0 24.2 1.0 N B:GLY272 4.1 17.4 1.0 CA B:2OP401 4.2 27.0 0.8 O B:LEU296 4.4 21.2 1.0 CA B:GLY297 4.4 25.5 1.0 C B:GLY297 4.5 23.2 1.0 O1 A:PO42002 4.6 26.1 1.0 CA B:GLY298 4.6 25.8 1.0 OD1 B:ASP295 4.7 22.3 1.0 C B:GLY272 4.7 18.5 1.0 N B:ALA273 4.7 15.8 1.0 CB B:2OP401 4.7 17.4 0.8 O5P A:COA2001 4.7 21.2 1.0 S1P A:COA2001 4.8 27.3 1.0 C2P A:COA2001 4.8 23.3 1.0 CG2 A:THR164 4.9 19.8 1.0

R.L.Liu, X.L.Ren, H.X.Feng, X.L.Sheng, L.T.Li, Y.Zhang, H.Huang, Y.M.Zhao. Nuclear Gtpscs Functions As A Lactyl-Coa Ligase to Promote Histone Lactylation and Glioma Progression To Be Published.