Magnesium in PDB 8zru: Structure of Human ECHS1 in Apo State

All present enzymatic activity of Structure of Human ECHS1 in Apo State:
4.2.1.17; 5.3.3.8;

The binding sites of Magnesium atom in the Structure of Human ECHS1 in Apo State (pdb code 8zru). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of Human ECHS1 in Apo State, PDB code: 8zru:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Structure of Human ECHS1 in Apo State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Human ECHS1 in Apo State within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg301 b:87.7 occ:1.00 O C:ALA206 3.7 80.4 1.0 O A:ALA206 3.8 80.4 1.0 O B:ALA206 3.8 80.4 1.0 C C:ALA206 4.3 80.1 1.0 C B:ALA206 4.4 80.1 1.0 C A:ALA206 4.4 80.1 1.0 O A:GLN205 4.5 80.4 1.0 O C:GLN205 4.5 80.4 1.0 O B:GLN205 4.6 80.4 1.0 CA A:ALA206 4.8 80.1 1.0 CA C:ALA206 4.9 80.1 1.0 CA B:ALA206 4.9 80.1 1.0 O C:ALA182 5.0 76.4 1.0

Magnesium binding site 2 out of 2 in the Structure of Human ECHS1 in Apo State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of Human ECHS1 in Apo State within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg301 b:87.7 occ:1.00 O D:ALA206 3.6 80.4 1.0 O E:ALA206 3.8 80.4 1.0 O F:ALA206 3.8 80.4 1.0 C D:ALA206 4.2 80.1 1.0 C F:ALA206 4.4 80.1 1.0 C E:ALA206 4.4 80.1 1.0 O D:GLN205 4.4 80.4 1.0 O E:GLN205 4.5 80.4 1.0 O F:GLN205 4.5 80.4 1.0 CA D:ALA206 4.7 80.1 1.0 CA E:ALA206 4.9 80.1 1.0 CA F:ALA206 4.9 80.1 1.0 O D:ALA182 5.0 76.4 1.0

G.Su, Y.Xu, B.Chen, K.Ju, Y.Jin, H.Chen, S.Zhang, X.Luan. Structural and Biochemical Mechanism of Short-Chain Enoyl-Coa Hydratase (ECHS1) Substrate Recognition. Commun Biol V. 8 619 2025.
ISSN: ESSN 2399-3642
PubMed: 40240482
DOI: 10.1038/S42003-025-07924-0