Magnesium in PDB 9btm: Nras 1-169 Q61R in Complex with SHOC2 80-582

All present enzymatic activity of Nras 1-169 Q61R in Complex with SHOC2 80-582:
3.6.5.2;

The structure of Nras 1-169 Q61R in Complex with SHOC2 80-582, PDB code: 9btm was solved by Z.J.Hauseman, D.King, J.Viscomi, M.Fodor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	59.88 / 2.73
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	78.884, 89.339, 119.768, 90, 90, 90
R / Rfree (%)	20.2 / 23.8

The binding sites of Magnesium atom in the Nras 1-169 Q61R in Complex with SHOC2 80-582 (pdb code 9btm). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Nras 1-169 Q61R in Complex with SHOC2 80-582, PDB code: 9btm:

Magnesium binding site 1 out of 1 in the Nras 1-169 Q61R in Complex with SHOC2 80-582


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Nras 1-169 Q61R in Complex with SHOC2 80-582 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg202 b:61.2 occ:1.00 O1B A:GTP201 2.0 57.8 1.0 O A:HOH305 2.0 61.2 1.0 OG1 A:THR35 2.1 59.1 1.0 OG A:SER17 2.1 64.6 1.0 O A:HOH303 2.2 61.3 1.0 O2G A:GTP201 2.2 63.5 1.0 CB A:THR35 2.9 50.6 1.0 PG A:GTP201 3.2 65.9 1.0 PB A:GTP201 3.2 63.4 1.0 CB A:SER17 3.4 63.4 1.0 O3G A:GTP201 3.5 56.2 1.0 O3B A:GTP201 3.6 70.0 1.0 N A:THR35 3.8 54.9 1.0 OD2 A:ASP57 3.9 67.5 1.0 CG2 A:THR35 3.9 58.2 1.0 CA A:THR35 4.0 55.4 1.0 O A:HOH302 4.0 55.3 1.0 N A:SER17 4.0 58.8 1.0 O2B A:GTP201 4.0 64.2 1.0 O1A A:GTP201 4.0 69.5 1.0 CA A:SER17 4.2 57.5 1.0 O A:THR58 4.3 65.0 1.0 OD1 A:ASP57 4.3 66.0 1.0 O3A A:GTP201 4.4 64.1 1.0 CG A:ASP57 4.5 64.3 1.0 O A:ASP33 4.5 62.1 1.0 O1G A:GTP201 4.5 72.6 1.0 PA A:GTP201 4.7 66.4 1.0 C A:PRO34 4.8 61.1 1.0 O2A A:GTP201 4.8 62.0 1.0 NZ A:LYS16 4.9 59.2 1.0 CB A:LYS16 4.9 58.7 1.0 CE A:LYS16 4.9 58.3 1.0 C A:LYS16 5.0 55.2 1.0

Z.J.Hauseman, F.Stauffer, K.S.Beyer, S.Molle, E.Cavicchioli, J.R.Marchand, M.Fodor, J.Viscomi, C.Handl, A.Dhembi, S.Katz, B.Faggion, G.Kerr, D.Schildknecht, D.Maddalo, C.Pissot Solderman, J.Brady, O.Shrestha, Z.Nguyen, L.Leder, G.Cremosnik, S.Lopez Romero, U.Hassiepen, T.Stams, M.Linder, G.G.Galli, D.A.Guthy, D.A.King, S.M.Maira, C.R.Thoma, V.Ehmke, L.Tordella. Disruption of SHOC2-Ras Interaction For Therapeutic Targeting of Ras-Mutant Cancers To Be Published.