Magnesium in PDB 9bw4: TXNL1-Bound Proteasome

All present enzymatic activity of TXNL1-Bound Proteasome:
3.4.25.1;

The structure of TXNL1-Bound Proteasome also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Magnesium atom in the TXNL1-Bound Proteasome (pdb code 9bw4). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 5 binding sites of Magnesium where determined in the TXNL1-Bound Proteasome, PDB code: 9bw4:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5;

Magnesium binding site 1 out of 5 in the TXNL1-Bound Proteasome


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of TXNL1-Bound Proteasome within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg502 b:66.5 occ:1.00 O2G A:ATP501 1.8 69.0 1.0 OG1 A:THR223 2.5 67.5 1.0 O1B A:ATP501 2.6 69.0 1.0 PG A:ATP501 2.9 69.0 1.0 O3B A:ATP501 3.2 69.0 1.0 PB A:ATP501 3.4 69.0 1.0 O1G A:ATP501 3.5 69.0 1.0 CB A:THR223 3.8 67.5 1.0 NH2 B:ARG346 4.0 67.8 1.0 O1A A:ATP501 4.1 69.0 1.0 O3A A:ATP501 4.2 69.0 1.0 O3G A:ATP501 4.2 69.0 1.0 OD1 A:ASP275 4.2 74.7 1.0 O B:ASP317 4.5 69.8 1.0 N A:THR223 4.6 67.5 1.0 CG2 A:THR223 4.6 67.5 1.0 PA A:ATP501 4.7 69.0 1.0 O2B A:ATP501 4.8 69.0 1.0 CA A:THR223 4.8 67.5 1.0 OD2 A:ASP275 4.8 74.7 1.0 NH1 B:ARG343 4.9 66.9 1.0 CG A:ASP275 4.9 74.7 1.0

Magnesium binding site 2 out of 5 in the TXNL1-Bound Proteasome


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of TXNL1-Bound Proteasome within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg502 b:61.7 occ:1.00 O1A B:ATP501 1.8 66.7 1.0 O3A B:ATP501 2.2 66.7 1.0 PA B:ATP501 2.3 66.7 1.0 CB B:THR233 2.4 66.8 1.0 O3B B:ATP501 2.4 66.7 1.0 OG1 B:THR233 2.4 66.8 1.0 O2G B:ATP501 2.7 66.7 1.0 PB B:ATP501 2.7 66.7 1.0 N B:THR233 2.8 66.8 1.0 O2B B:ATP501 3.0 66.7 1.0 PG B:ATP501 3.1 66.7 1.0 CA B:THR233 3.1 66.8 1.0 O5' B:ATP501 3.2 66.7 1.0 CG2 B:THR233 3.7 66.8 1.0 O2A B:ATP501 3.7 66.7 1.0 C B:LYS232 3.9 65.5 1.0 O1G B:ATP501 4.0 66.7 1.0 C5' B:ATP501 4.0 66.7 1.0 O1B B:ATP501 4.1 66.7 1.0 N B:LYS232 4.1 65.5 1.0 C B:THR233 4.1 66.8 1.0 O3G B:ATP501 4.3 66.7 1.0 N B:LEU234 4.3 67.0 1.0 CA B:LYS232 4.4 65.5 1.0 NH1 C:ARG307 4.4 65.4 1.0 CB B:LYS232 4.5 65.5 1.0 C B:GLY231 4.6 67.4 1.0 O B:LYS232 4.8 65.5 1.0 CD1 B:LEU234 5.0 67.0 1.0

Magnesium binding site 3 out of 5 in the TXNL1-Bound Proteasome


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of TXNL1-Bound Proteasome within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg502 b:57.1 occ:1.00 O2B C:ATP501 1.7 62.0 1.0 O3B C:ATP501 2.0 62.0 1.0 O1G C:ATP501 2.0 62.0 1.0 PG C:ATP501 2.1 62.0 1.0 PB C:ATP501 2.1 62.0 1.0 O3G C:ATP501 2.4 62.0 1.0 O1B C:ATP501 2.9 62.0 1.0 OD2 C:ASP249 3.1 65.4 1.0 O3A C:ATP501 3.5 62.0 1.0 O2G C:ATP501 3.6 62.0 1.0 OE2 C:GLU250 3.6 66.7 1.0 OD1 C:ASP249 3.6 65.4 1.0 OG1 C:THR197 3.7 61.0 1.0 CG C:ASP249 3.8 65.4 1.0 CD C:GLU250 4.3 66.7 1.0 NH2 D:ARG323 4.3 66.8 1.0 CB C:THR197 4.6 61.0 1.0 CG C:GLU250 4.9 66.7 1.0 OE1 C:GLU250 4.9 66.7 1.0 PA C:ATP501 5.0 62.0 1.0

Magnesium binding site 4 out of 5 in the TXNL1-Bound Proteasome


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of TXNL1-Bound Proteasome within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg502 b:62.9 occ:1.00 OG1 D:THR213 1.8 68.4 1.0 CB D:THR213 2.6 68.4 1.0 CG2 D:THR213 2.6 68.4 1.0 O1B D:ADP501 3.0 66.6 1.0 O2A D:ADP501 3.2 66.6 1.0 OD2 D:ASP265 3.3 73.7 1.0 NH2 D:ARG229 3.5 72.5 1.0 OD1 D:ASP265 3.6 73.7 1.0 CG D:ASP265 3.9 73.7 1.0 CA D:THR213 4.0 68.4 1.0 PB D:ADP501 4.3 66.6 1.0 PA D:ADP501 4.4 66.6 1.0 N D:THR213 4.5 68.4 1.0 CZ D:ARG229 4.6 72.5 1.0 O3B D:ADP501 4.7 66.6 1.0 O1A D:ADP501 4.8 66.6 1.0 NH1 D:ARG229 4.9 72.5 1.0 O3A D:ADP501 5.0 66.6 1.0

Magnesium binding site 5 out of 5 in the TXNL1-Bound Proteasome


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of TXNL1-Bound Proteasome within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg402 b:112.2 occ:1.00 O2A E:ADP401 1.8 115.8 1.0 O1A E:ADP401 2.1 115.8 1.0 PA E:ADP401 2.3 115.8 1.0 N E:THR181 2.6 114.2 1.0 CG2 E:THR181 2.7 114.2 1.0 N E:LYS180 2.9 115.0 1.0 CB E:THR181 3.4 114.2 1.0 CG E:LYS180 3.4 115.0 1.0 O5' E:ADP401 3.4 115.8 1.0 CA E:THR181 3.4 114.2 1.0 C E:GLY179 3.4 115.7 1.0 N E:LEU182 3.5 117.1 1.0 C E:LYS180 3.5 115.0 1.0 O3A E:ADP401 3.5 115.8 1.0 CA E:LYS180 3.6 115.0 1.0 CA E:GLY179 3.7 115.7 1.0 C E:THR181 3.9 114.2 1.0 O2B E:ADP401 4.0 115.8 1.0 CB E:LYS180 4.0 115.0 1.0 N E:GLY179 4.2 115.7 1.0 PB E:ADP401 4.3 115.8 1.0 O E:GLY179 4.3 115.7 1.0 O1B E:ADP401 4.4 115.8 1.0 O E:GLY177 4.4 113.9 1.0 C5' E:ADP401 4.4 115.8 1.0 O E:LYS180 4.6 115.0 1.0 CB E:LEU182 4.6 117.1 1.0 CA E:LEU182 4.7 117.1 1.0 CD E:LYS180 4.7 115.0 1.0 OG1 E:THR181 4.8 114.2 1.0 NZ E:LYS180 4.8 115.0 1.0

J.Gao, C.Nardone, M.C.J.Yip, H.Chino, X.Gu, M.J.Rale, J.A.Paulo, M.E.Greenberg, S.Shao, S.J.Elledge. Structure of the TXNL1-Bound Proteasome To Be Published.