Magnesium in PDB 9e6r: BCL11A ZF4-6 in Complex with A Dna Sequence Observed in the Human Globin Locus Containing Motif Tgacca

The structure of BCL11A ZF4-6 in Complex with A Dna Sequence Observed in the Human Globin Locus Containing Motif Tgacca, PDB code: 9e6r was solved by J.R.Horton, X.Cheng, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.93 / 2.09
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	61.328, 61.328, 244.41, 90, 90, 90
R / Rfree (%)	20.4 / 23.8

The structure of BCL11A ZF4-6 in Complex with A Dna Sequence Observed in the Human Globin Locus Containing Motif Tgacca also contains other interesting chemical elements:

Zinc

(Zn)

8 atoms

The binding sites of Magnesium atom in the BCL11A ZF4-6 in Complex with A Dna Sequence Observed in the Human Globin Locus Containing Motif Tgacca (pdb code 9e6r). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the BCL11A ZF4-6 in Complex with A Dna Sequence Observed in the Human Globin Locus Containing Motif Tgacca, PDB code: 9e6r:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the BCL11A ZF4-6 in Complex with A Dna Sequence Observed in the Human Globin Locus Containing Motif Tgacca


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of BCL11A ZF4-6 in Complex with A Dna Sequence Observed in the Human Globin Locus Containing Motif Tgacca within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1007 b:36.4 occ:1.00 O1 A:EDO1005 3.2 53.0 1.0 N A:LYS752 3.2 45.3 1.0 O B:HOH209 3.2 42.1 1.0 ND2 A:ASN756 3.3 37.0 1.0 O B:HOH215 3.5 39.2 1.0 C1 A:EDO1005 3.7 56.8 1.0 CB A:LYS752 3.7 45.9 1.0 CD2 A:PHE751 4.0 46.1 1.0 CA A:LYS752 4.0 45.8 1.0 CA A:PHE751 4.0 45.3 1.0 CB A:PHE751 4.0 48.2 1.0 C A:PHE751 4.1 49.5 1.0 CG A:LYS752 4.1 47.5 1.0 CB A:ASN756 4.2 39.0 1.0 CG A:ASN756 4.2 45.3 1.0 ND2 A:ASN753 4.4 41.8 1.0 CG A:PHE751 4.5 54.2 1.0 N A:ASN753 4.6 47.9 1.0 C2' B:DC16 4.7 44.0 1.0 C A:LYS752 4.7 46.4 1.0 CD A:LYS752 4.7 54.2 1.0 C2 A:EDO1005 4.9 59.9 1.0 OP2 B:DA17 4.9 45.9 1.0 CG A:ASN753 4.9 47.4 1.0 O2 A:EDO1005 4.9 69.3 1.0

Magnesium binding site 2 out of 2 in the BCL11A ZF4-6 in Complex with A Dna Sequence Observed in the Human Globin Locus Containing Motif Tgacca


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of BCL11A ZF4-6 in Complex with A Dna Sequence Observed in the Human Globin Locus Containing Motif Tgacca within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg101 b:58.3 occ:1.00 O B:HOH233 2.1 64.2 1.0 O C:HOH1204 2.1 49.0 1.0 O B:HOH227 2.1 53.2 1.0 O B:HOH213 2.2 53.2 1.0 O C:HOH1223 2.2 56.1 1.0 O B:HOH232 2.2 55.4 1.0 O C:HOH1215 3.9 48.2 1.0 O4' C:DG5 4.3 44.1 1.0 O4' B:DG19 4.4 48.2 1.0 O B:HOH224 4.4 49.7 1.0 O2 C:DT4 4.5 37.0 1.0 N3 B:DA18 4.6 38.1 1.0 C4' C:DG5 4.7 46.9 1.0 C5' B:DG19 4.7 49.7 1.0 C4' B:DG19 4.7 51.1 1.0 O4' B:DA18 4.9 41.5 1.0 C1' B:DA18 5.0 45.5 1.0

J.R.Horton, M.Yu, J.Zhou, M.Tran, R.R.Anakal, Y.Lu, R.M.Blumenthal, X.Zhang, Y.Huang, X.Zhang, X.Cheng. Transcription Factor BCL11A Utilizes Two Zinc-Finger Tandem Arrays to Bind Clustered Short Sequence Motifs To Be Published.