Magnesium in PDB 9fso: Human Rna Polymerase III Class III Open Pre-Initiation Complex 1 (OC1)

All present enzymatic activity of Human Rna Polymerase III Class III Open Pre-Initiation Complex 1 (OC1):
2.7.7.6;

The structure of Human Rna Polymerase III Class III Open Pre-Initiation Complex 1 (OC1) also contains other interesting chemical elements:

Zinc	(Zn)	9 atoms
Iron	(Fe)	4 atoms

The binding sites of Magnesium atom in the Human Rna Polymerase III Class III Open Pre-Initiation Complex 1 (OC1) (pdb code 9fso). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human Rna Polymerase III Class III Open Pre-Initiation Complex 1 (OC1), PDB code: 9fso:

Magnesium binding site 1 out of 1 in the Human Rna Polymerase III Class III Open Pre-Initiation Complex 1 (OC1)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human Rna Polymerase III Class III Open Pre-Initiation Complex 1 (OC1) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1403 b:24.0 occ:1.00 OD1 A:ASP501 2.0 25.6 1.0 OD1 A:ASP499 2.1 54.7 1.0 OD2 A:ASP501 2.3 25.6 1.0 OD1 A:ASP503 2.3 20.6 1.0 CG A:ASP501 2.4 25.6 1.0 CG A:ASP499 2.8 54.7 1.0 OD2 A:ASP499 2.8 54.7 1.0 CG A:ASP503 3.0 20.6 1.0 OD2 A:ASP503 3.0 20.6 1.0 CB A:ASP501 3.8 25.6 1.0 N A:ASP501 4.2 25.6 1.0 CB A:ASP499 4.2 54.7 1.0 CB A:ASP503 4.3 20.6 1.0 CA A:ASP501 4.4 25.6 1.0 C A:ASP501 4.6 25.6 1.0 O A:ASP501 4.6 25.6 1.0 N A:ASP499 4.7 54.7 1.0 CA A:ASP499 4.8 54.7 1.0 N A:ASP503 4.8 20.6 1.0 NH2 A:ARG464 4.9 12.8 1.0 C A:ASP499 4.9 54.7 1.0 CA A:ASP503 5.0 20.6 1.0 N A:PHE500 5.0 27.2 1.0

S.Z.Shah, T.N.Perry, A.Graziadei, V.Cecatiello, T.Kaliyappan, A.D.Misiaszek, C.W.Muller, E.P.Ramsay, A.Vannini. Structural Insights Into Distinct Mechanisms of Rna Polymerase II and III Recruitment to Snrna Promoters. Nat Commun V. 16 141 2025.
ISSN: ESSN 2041-1723
PubMed: 39747245
DOI: 10.1038/S41467-024-55553-8