Magnesium in PDB 9hra: Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid
Enzymatic activity of Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid
All present enzymatic activity of Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid:
4.1.3.30;
Protein crystallography data
The structure of Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid, PDB code: 9hra
was solved by
W.Stuart,
M.Isupov,
N.J.Harmer,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
52.59 /
2.48
|
Space group
|
P 1 21 1
|
Cell size a, b, c (Å), α, β, γ (°)
|
105.199,
101.203,
115.683,
90,
91.15,
90
|
R / Rfree (%)
|
20.8 /
25.7
|
Other elements in 9hra:
The structure of Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid
(pdb code 9hra). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 8 binding sites of Magnesium where determined in the
Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid, PDB code: 9hra:
Jump to Magnesium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Magnesium binding site 1 out
of 8 in 9hra
Go back to
Magnesium Binding Sites List in 9hra
Magnesium binding site 1 out
of 8 in the Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid
 Mono view
 Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg306
b:38.8
occ:1.00
|
OD2
|
A:ASP81
|
2.0
|
41.7
|
1.0
|
O
|
A:HOH418
|
2.0
|
28.7
|
1.0
|
O
|
A:HOH405
|
2.0
|
46.0
|
1.0
|
O
|
A:HOH404
|
2.0
|
39.8
|
1.0
|
O
|
A:PYR302
|
2.3
|
40.9
|
1.0
|
O3
|
A:PYR302
|
2.5
|
47.0
|
1.0
|
CG
|
A:ASP81
|
3.0
|
38.4
|
1.0
|
C
|
A:PYR302
|
3.1
|
50.8
|
1.0
|
CA
|
A:PYR302
|
3.2
|
54.3
|
1.0
|
OD1
|
A:ASP81
|
3.4
|
36.5
|
1.0
|
OD1
|
A:ASP83
|
3.6
|
70.5
|
1.0
|
OD2
|
A:ASP54
|
4.1
|
52.7
|
1.0
|
N
|
A:GLY44
|
4.1
|
41.7
|
1.0
|
CA
|
A:GLY43
|
4.1
|
43.4
|
1.0
|
N
|
A:GLY43
|
4.2
|
36.4
|
1.0
|
OXT
|
A:PYR302
|
4.3
|
41.1
|
1.0
|
CB
|
A:ASP81
|
4.3
|
29.4
|
1.0
|
O4
|
A:SIN301
|
4.3
|
85.1
|
1.0
|
OD1
|
A:ASP54
|
4.4
|
56.7
|
1.0
|
CE1
|
A:HIS108
|
4.4
|
28.0
|
1.0
|
OE1
|
A:GLU110
|
4.5
|
60.6
|
1.0
|
C
|
A:GLY43
|
4.5
|
37.9
|
1.0
|
CB
|
A:PYR302
|
4.6
|
59.8
|
1.0
|
NH2
|
A:ARG152
|
4.6
|
53.2
|
1.0
|
OH
|
A:TYR40
|
4.6
|
26.4
|
1.0
|
CG
|
A:ASP54
|
4.6
|
43.2
|
1.0
|
O1
|
A:EDO305
|
4.7
|
55.3
|
1.0
|
CG
|
A:ASP83
|
4.7
|
66.9
|
1.0
|
NE2
|
A:HIS108
|
5.0
|
30.4
|
1.0
|
|
Magnesium binding site 2 out
of 8 in 9hra
Go back to
Magnesium Binding Sites List in 9hra
Magnesium binding site 2 out
of 8 in the Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid
 Mono view
 Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Mg307
b:29.7
occ:1.00
|
OD2
|
B:ASP81
|
2.0
|
46.8
|
1.0
|
O
|
B:HOH417
|
2.0
|
26.6
|
1.0
|
O
|
B:HOH403
|
2.0
|
25.8
|
1.0
|
O
|
B:HOH408
|
2.0
|
26.8
|
1.0
|
OXT
|
B:PYR302
|
2.3
|
43.7
|
1.0
|
O3
|
B:PYR302
|
2.5
|
26.8
|
1.0
|
CG
|
B:ASP81
|
3.1
|
43.9
|
1.0
|
C
|
B:PYR302
|
3.1
|
44.0
|
1.0
|
CA
|
B:PYR302
|
3.2
|
39.6
|
1.0
|
OD1
|
B:ASP83
|
3.5
|
64.0
|
1.0
|
OD1
|
B:ASP81
|
3.5
|
37.4
|
1.0
|
OD2
|
B:ASP54
|
3.8
|
28.3
|
1.0
|
N
|
B:GLY44
|
3.8
|
29.1
|
1.0
|
CA
|
B:GLY43
|
3.9
|
29.9
|
1.0
|
N
|
B:GLY43
|
4.0
|
26.5
|
1.0
|
OD1
|
B:ASP54
|
4.1
|
50.9
|
1.0
|
O2
|
B:EDO305
|
4.2
|
58.5
|
1.0
|
C
|
B:GLY43
|
4.3
|
35.6
|
1.0
|
O3
|
B:SIN301
|
4.3
|
40.5
|
1.0
|
O
|
B:PYR302
|
4.3
|
38.8
|
1.0
|
CG
|
B:ASP54
|
4.4
|
33.9
|
1.0
|
CB
|
B:ASP81
|
4.4
|
41.8
|
1.0
|
CB
|
B:PYR302
|
4.6
|
31.4
|
1.0
|
CE1
|
B:HIS108
|
4.7
|
27.1
|
1.0
|
NH2
|
B:ARG152
|
4.7
|
45.9
|
1.0
|
CG
|
B:ASP83
|
4.7
|
58.0
|
1.0
|
OH
|
B:TYR40
|
4.7
|
23.4
|
1.0
|
OE1
|
B:GLU110
|
4.7
|
50.0
|
1.0
|
CA
|
B:GLY44
|
4.8
|
35.5
|
1.0
|
|
Magnesium binding site 3 out
of 8 in 9hra
Go back to
Magnesium Binding Sites List in 9hra
Magnesium binding site 3 out
of 8 in the Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid
 Mono view
 Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 3 of Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Mg304
b:62.0
occ:1.00
|
OD2
|
D:ASP81
|
2.0
|
47.5
|
1.0
|
O
|
D:HOH404
|
2.0
|
50.7
|
1.0
|
O
|
D:HOH402
|
2.0
|
32.7
|
1.0
|
O
|
D:HOH410
|
2.0
|
45.1
|
1.0
|
O3
|
D:PYR302
|
2.5
|
69.7
|
1.0
|
O
|
D:PYR302
|
2.6
|
52.6
|
1.0
|
CG
|
D:ASP81
|
3.0
|
51.1
|
1.0
|
CA
|
D:PYR302
|
3.3
|
59.3
|
1.0
|
C
|
D:PYR302
|
3.4
|
62.4
|
1.0
|
OD1
|
D:ASP81
|
3.5
|
60.3
|
1.0
|
OD1
|
D:ASP83
|
3.5
|
84.1
|
1.0
|
N
|
D:GLY44
|
3.9
|
36.2
|
1.0
|
OD2
|
D:ASP54
|
3.9
|
45.6
|
1.0
|
CA
|
D:GLY43
|
4.0
|
44.5
|
1.0
|
N
|
D:GLY43
|
4.1
|
39.0
|
1.0
|
OD1
|
D:ASP54
|
4.2
|
43.3
|
1.0
|
CB
|
D:ASP81
|
4.3
|
47.4
|
1.0
|
C
|
D:GLY43
|
4.4
|
33.3
|
1.0
|
CG
|
D:ASP54
|
4.5
|
57.2
|
1.0
|
O
|
D:HOH423
|
4.5
|
32.7
|
1.0
|
OXT
|
D:PYR302
|
4.5
|
58.7
|
1.0
|
CE1
|
D:HIS108
|
4.6
|
36.4
|
1.0
|
OH
|
D:TYR40
|
4.6
|
48.1
|
1.0
|
OE1
|
D:GLU110
|
4.7
|
54.1
|
1.0
|
NH2
|
D:ARG152
|
4.7
|
63.9
|
1.0
|
CB
|
D:PYR302
|
4.7
|
42.7
|
1.0
|
CG
|
D:ASP83
|
4.7
|
50.8
|
1.0
|
O4
|
D:SIN301
|
4.8
|
78.9
|
1.0
|
O3
|
D:SIN301
|
4.8
|
74.5
|
1.0
|
CA
|
D:GLY44
|
4.9
|
37.8
|
1.0
|
|
Magnesium binding site 4 out
of 8 in 9hra
Go back to
Magnesium Binding Sites List in 9hra
Magnesium binding site 4 out
of 8 in the Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid
 Mono view
 Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 4 of Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Mg308
b:45.1
occ:1.00
|
OD2
|
F:ASP81
|
2.0
|
48.7
|
1.0
|
O
|
F:HOH401
|
2.0
|
39.5
|
1.0
|
O
|
F:HOH407
|
2.0
|
50.0
|
1.0
|
O
|
F:HOH405
|
2.0
|
35.4
|
1.0
|
OXT
|
F:PYR303
|
2.3
|
36.2
|
1.0
|
O3
|
F:PYR303
|
2.5
|
44.3
|
1.0
|
CG
|
F:ASP81
|
3.0
|
54.2
|
1.0
|
C
|
F:PYR303
|
3.1
|
48.2
|
1.0
|
CA
|
F:PYR303
|
3.2
|
54.4
|
1.0
|
OD1
|
F:ASP83
|
3.3
|
54.9
|
1.0
|
OD1
|
F:ASP81
|
3.4
|
55.0
|
1.0
|
OD2
|
F:ASP54
|
4.1
|
43.0
|
1.0
|
N
|
F:GLY44
|
4.1
|
45.3
|
1.0
|
CA
|
F:GLY43
|
4.1
|
48.9
|
1.0
|
N
|
F:GLY43
|
4.2
|
40.0
|
1.0
|
OD1
|
F:ASP54
|
4.3
|
56.4
|
1.0
|
O
|
F:PYR303
|
4.3
|
47.8
|
1.0
|
CB
|
F:ASP81
|
4.3
|
40.5
|
1.0
|
CE1
|
F:HIS108
|
4.4
|
40.0
|
1.0
|
OE1
|
F:GLU110
|
4.5
|
58.9
|
1.0
|
NH2
|
F:ARG152
|
4.5
|
66.5
|
1.0
|
O3
|
F:SIN302
|
4.5
|
64.7
|
1.0
|
C
|
F:GLY43
|
4.5
|
37.8
|
1.0
|
CG
|
F:ASP83
|
4.6
|
55.9
|
1.0
|
CG
|
F:ASP54
|
4.6
|
41.5
|
1.0
|
CB
|
F:PYR303
|
4.7
|
38.5
|
1.0
|
OH
|
F:TYR40
|
4.7
|
42.3
|
1.0
|
|
Magnesium binding site 5 out
of 8 in 9hra
Go back to
Magnesium Binding Sites List in 9hra
Magnesium binding site 5 out
of 8 in the Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid
 Mono view
 Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 5 of Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Mg308
b:51.0
occ:1.00
|
OD2
|
G:ASP81
|
2.0
|
42.3
|
1.0
|
O
|
G:HOH411
|
2.0
|
54.9
|
1.0
|
O
|
G:HOH405
|
2.0
|
33.9
|
1.0
|
O
|
G:HOH407
|
2.0
|
28.8
|
1.0
|
OXT
|
G:PYR302
|
2.3
|
46.1
|
1.0
|
O3
|
G:PYR302
|
2.5
|
58.8
|
1.0
|
CG
|
G:ASP81
|
3.0
|
30.7
|
1.0
|
C
|
G:PYR302
|
3.1
|
47.5
|
1.0
|
CA
|
G:PYR302
|
3.2
|
53.7
|
1.0
|
OD1
|
G:ASP81
|
3.4
|
29.9
|
1.0
|
OD1
|
G:ASP83
|
3.5
|
43.6
|
1.0
|
OD2
|
G:ASP54
|
4.0
|
37.5
|
1.0
|
O1
|
G:EDO305
|
4.1
|
40.4
|
1.0
|
N
|
G:GLY44
|
4.1
|
34.9
|
1.0
|
CA
|
G:GLY43
|
4.1
|
33.4
|
1.0
|
N
|
G:GLY43
|
4.2
|
27.4
|
1.0
|
O
|
G:PYR302
|
4.3
|
44.8
|
1.0
|
CB
|
G:ASP81
|
4.3
|
25.1
|
1.0
|
OD1
|
G:ASP54
|
4.4
|
34.7
|
1.0
|
O3
|
G:SIN301
|
4.4
|
40.0
|
1.0
|
CE1
|
G:HIS108
|
4.5
|
36.2
|
1.0
|
C
|
G:GLY43
|
4.5
|
39.1
|
1.0
|
NH2
|
G:ARG152
|
4.5
|
38.5
|
1.0
|
OE1
|
G:GLU110
|
4.5
|
40.4
|
1.0
|
CB
|
G:PYR302
|
4.6
|
49.4
|
1.0
|
OH
|
G:TYR40
|
4.6
|
39.8
|
1.0
|
CG
|
G:ASP54
|
4.6
|
34.2
|
1.0
|
CG
|
G:ASP83
|
4.7
|
48.5
|
1.0
|
C1
|
G:EDO305
|
4.8
|
47.2
|
1.0
|
|
Magnesium binding site 6 out
of 8 in 9hra
Go back to
Magnesium Binding Sites List in 9hra
Magnesium binding site 6 out
of 8 in the Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid
 Mono view
 Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 6 of Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
I:Mg306
b:36.7
occ:1.00
|
OD2
|
I:ASP81
|
2.0
|
44.1
|
1.0
|
O
|
I:HOH428
|
2.0
|
47.8
|
1.0
|
O
|
I:HOH408
|
2.0
|
43.2
|
1.0
|
O
|
I:HOH412
|
2.0
|
44.6
|
1.0
|
O
|
I:PYR302
|
2.3
|
34.3
|
1.0
|
O3
|
I:PYR302
|
2.5
|
35.8
|
1.0
|
CG
|
I:ASP81
|
3.1
|
37.4
|
1.0
|
C
|
I:PYR302
|
3.1
|
43.7
|
1.0
|
CA
|
I:PYR302
|
3.2
|
47.6
|
1.0
|
OD1
|
I:ASP81
|
3.5
|
42.9
|
1.0
|
OD1
|
I:ASP83
|
3.5
|
67.6
|
1.0
|
N
|
I:GLY44
|
3.9
|
28.7
|
1.0
|
O1
|
I:EDO304
|
3.9
|
58.3
|
1.0
|
CA
|
I:GLY43
|
3.9
|
34.4
|
1.0
|
OD2
|
I:ASP54
|
4.0
|
34.5
|
1.0
|
N
|
I:GLY43
|
4.0
|
38.3
|
1.0
|
OD1
|
I:ASP54
|
4.2
|
66.5
|
1.0
|
OXT
|
I:PYR302
|
4.3
|
30.2
|
1.0
|
C
|
I:GLY43
|
4.3
|
30.4
|
1.0
|
O3
|
I:SIN301
|
4.3
|
81.7
|
1.0
|
CB
|
I:ASP81
|
4.3
|
32.7
|
1.0
|
C1
|
I:EDO304
|
4.4
|
42.4
|
1.0
|
CG
|
I:ASP54
|
4.5
|
43.7
|
1.0
|
CB
|
I:PYR302
|
4.6
|
36.6
|
1.0
|
CE1
|
I:HIS108
|
4.6
|
30.9
|
1.0
|
OH
|
I:TYR40
|
4.7
|
54.6
|
1.0
|
CG
|
I:ASP83
|
4.7
|
72.8
|
1.0
|
NH2
|
I:ARG152
|
4.7
|
85.0
|
1.0
|
OE1
|
I:GLU110
|
4.7
|
84.4
|
1.0
|
CA
|
I:GLY44
|
4.9
|
28.6
|
1.0
|
|
Magnesium binding site 7 out
of 8 in 9hra
Go back to
Magnesium Binding Sites List in 9hra
Magnesium binding site 7 out
of 8 in the Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid
 Mono view
 Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 7 of Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
J:Mg307
b:29.4
occ:1.00
|
OD2
|
J:ASP81
|
2.0
|
31.7
|
1.0
|
O
|
J:HOH416
|
2.0
|
29.1
|
1.0
|
O
|
J:HOH423
|
2.0
|
24.5
|
1.0
|
O
|
J:HOH429
|
2.0
|
36.0
|
1.0
|
O3
|
J:PYR302
|
2.5
|
31.2
|
1.0
|
OXT
|
J:PYR302
|
2.5
|
34.1
|
1.0
|
CG
|
J:ASP81
|
3.0
|
34.2
|
1.0
|
CA
|
J:PYR302
|
3.2
|
37.6
|
1.0
|
C
|
J:PYR302
|
3.3
|
42.6
|
1.0
|
OD1
|
J:ASP81
|
3.4
|
38.7
|
1.0
|
OD1
|
J:ASP83
|
3.6
|
54.3
|
1.0
|
CE1
|
J:HIS108
|
4.2
|
27.5
|
1.0
|
OD2
|
J:ASP54
|
4.3
|
35.2
|
1.0
|
N
|
J:GLY44
|
4.3
|
30.2
|
1.0
|
CB
|
J:ASP81
|
4.3
|
24.0
|
1.0
|
CA
|
J:GLY43
|
4.3
|
46.9
|
1.0
|
NH2
|
J:ARG152
|
4.3
|
51.6
|
1.0
|
OE1
|
J:GLU110
|
4.3
|
54.5
|
1.0
|
N
|
J:GLY43
|
4.3
|
38.7
|
1.0
|
O1
|
J:EDO306
|
4.3
|
85.2
|
1.0
|
O
|
J:PYR302
|
4.5
|
38.9
|
1.0
|
OH
|
J:TYR40
|
4.5
|
25.3
|
1.0
|
OD1
|
J:ASP54
|
4.6
|
44.2
|
1.0
|
CB
|
J:PYR302
|
4.7
|
34.5
|
1.0
|
C
|
J:GLY43
|
4.7
|
44.5
|
1.0
|
CG
|
J:ASP83
|
4.8
|
55.0
|
1.0
|
O4
|
J:SIN301
|
4.8
|
64.7
|
1.0
|
NE2
|
J:HIS108
|
4.8
|
26.9
|
1.0
|
CG
|
J:ASP54
|
4.8
|
45.6
|
1.0
|
|
Magnesium binding site 8 out
of 8 in 9hra
Go back to
Magnesium Binding Sites List in 9hra
Magnesium binding site 8 out
of 8 in the Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid
 Mono view
 Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 8 of Crystal Structure of the Coxiella Burnetii 2-Methylisocitrate Lyase Bound to Products Succinic and Pyruvic Acid within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
L:Mg307
b:41.9
occ:1.00
|
OD2
|
L:ASP81
|
2.0
|
38.6
|
1.0
|
O
|
L:HOH404
|
2.0
|
26.0
|
1.0
|
O
|
L:HOH406
|
2.0
|
42.0
|
1.0
|
O
|
L:HOH422
|
2.0
|
38.2
|
1.0
|
OXT
|
L:PYR302
|
2.3
|
36.5
|
1.0
|
O3
|
L:PYR302
|
2.5
|
38.9
|
1.0
|
CG
|
L:ASP81
|
3.0
|
39.9
|
1.0
|
C
|
L:PYR302
|
3.1
|
39.2
|
1.0
|
CA
|
L:PYR302
|
3.2
|
37.7
|
1.0
|
OD1
|
L:ASP81
|
3.3
|
37.1
|
1.0
|
OD1
|
L:ASP83
|
3.4
|
51.3
|
1.0
|
CA
|
L:GLY43
|
4.1
|
34.4
|
1.0
|
N
|
L:GLY44
|
4.2
|
32.1
|
1.0
|
OD2
|
L:ASP54
|
4.2
|
50.2
|
1.0
|
N
|
L:GLY43
|
4.2
|
38.3
|
1.0
|
O1
|
L:EDO305
|
4.2
|
58.2
|
1.0
|
CB
|
L:ASP81
|
4.3
|
36.2
|
1.0
|
O
|
L:PYR302
|
4.3
|
40.1
|
1.0
|
OD1
|
L:ASP54
|
4.4
|
50.5
|
1.0
|
CE1
|
L:HIS108
|
4.4
|
30.7
|
1.0
|
OE1
|
L:GLU110
|
4.5
|
53.3
|
1.0
|
NH2
|
L:ARG152
|
4.5
|
48.3
|
1.0
|
O3
|
L:SIN301
|
4.5
|
55.1
|
1.0
|
C
|
L:GLY43
|
4.6
|
44.6
|
1.0
|
CG
|
L:ASP83
|
4.6
|
53.2
|
1.0
|
OH
|
L:TYR40
|
4.7
|
25.4
|
1.0
|
CB
|
L:PYR302
|
4.7
|
29.9
|
1.0
|
CG
|
L:ASP54
|
4.7
|
46.0
|
1.0
|
NE2
|
L:HIS108
|
5.0
|
27.5
|
1.0
|
|
Reference:
W.S.Stuart,
C.H.Jenkins,
P.M.Ireland,
M.N.Isupov,
I.H.Norville,
N.J.Harmer.
Structure and Catalytic Mechanism of Methylisocitrate Lyase, A Potential Drug Target Against Coxiella Burnetii. J.Biol.Chem. V. 301 08517 2025.
ISSN: ESSN 1083-351X
PubMed: 40250561
DOI: 10.1016/J.JBC.2025.108517
Page generated: Sat Aug 23 06:02:47 2025
|