Magnesium in PDB 9hwg: Structure of the Transcribing Pol II-Tcr-RECQL5 Complex

All present enzymatic activity of Structure of the Transcribing Pol II-Tcr-RECQL5 Complex:
2.7.7.6; 5.6.2.4;

The structure of Structure of the Transcribing Pol II-Tcr-RECQL5 Complex also contains other interesting chemical elements:

Zinc

(Zn)

10 atoms

The binding sites of Magnesium atom in the Structure of the Transcribing Pol II-Tcr-RECQL5 Complex (pdb code 9hwg). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of the Transcribing Pol II-Tcr-RECQL5 Complex, PDB code: 9hwg:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Structure of the Transcribing Pol II-Tcr-RECQL5 Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of the Transcribing Pol II-Tcr-RECQL5 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2003 b:68.3 occ:1.00 OD2 A:ASP495 2.0 60.2 1.0 OD1 A:ASP499 2.1 63.1 1.0 OD1 A:ASP497 2.3 63.0 1.0 O3' P:A10 2.6 37.2 1.0 CG A:ASP495 2.9 60.2 1.0 CG A:ASP499 2.9 63.1 1.0 OD2 A:ASP499 3.1 63.1 1.0 OD1 A:ASP495 3.2 60.2 1.0 CG A:ASP497 3.2 63.0 1.0 OD2 A:ASP497 3.5 63.0 1.0 C3' P:A10 3.9 37.2 1.0 O2' P:A10 4.1 37.2 1.0 CB A:ASP495 4.3 60.2 1.0 O A:ASP495 4.3 60.2 1.0 CB A:ASP499 4.3 63.1 1.0 N A:ASP495 4.4 60.2 1.0 C4' P:A10 4.5 37.2 1.0 C A:ASP495 4.5 60.2 1.0 CB A:ASP497 4.6 63.0 1.0 C2' P:A10 4.6 37.2 1.0 CA A:ASP495 4.6 60.2 1.0 O A:ASP497 4.6 63.0 1.0 N A:ASP497 4.7 63.0 1.0 N A:ASP499 4.8 63.1 1.0 C A:ASP497 4.8 63.0 1.0 CA A:ASP499 4.9 63.1 1.0 CA A:ASP497 4.9 63.0 1.0

Magnesium binding site 2 out of 2 in the Structure of the Transcribing Pol II-Tcr-RECQL5 Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of the Transcribing Pol II-Tcr-RECQL5 Complex within 5.0Å range: probe atom residue distance (Å) B Occ b:Mg1501 b:269.5 occ:1.00 OD2 b:ASP646 3.6 230.0 1.0 OD1 b:ASP646 3.6 230.0 1.0 OG1 b:THR539 3.7 198.3 1.0 CG b:ASP646 4.0 230.0 1.0 O b:GLY920 4.2 296.9 1.0 CA b:GLY920 4.3 296.9 1.0 OE2 b:GLU647 4.3 237.9 1.0 C b:GLY920 4.7 296.9 1.0 NE2 b:GLN580 4.8 262.5 1.0 CD b:GLU647 4.9 237.9 1.0 CB b:THR539 4.9 198.3 1.0 N b:THR539 5.0 198.3 1.0 NH1 b:ARG950 5.0 327.3 1.0

L.Zhang, Y.Gordiyenko, T.Morgan, C.Franco, A.Tufegdzic Vidakovic, S.Zhang. Structural Basis of RECQL5-Induced Rna Polymerase II Transcription Braking and Subsequent Reactivation. Nat.Struct.Mol.Biol. 2025.
ISSN: ESSN 1545-9985
PubMed: 40624163
DOI: 10.1038/S41594-025-01586-6