Magnesium in PDB 9iqy: Cryo-Em Structure of Human TRPV4 Intracellular Domain in Complex with Gtpase Rhoa

All present enzymatic activity of Cryo-Em Structure of Human TRPV4 Intracellular Domain in Complex with Gtpase Rhoa:
3.6.5.2;

The binding sites of Magnesium atom in the Cryo-Em Structure of Human TRPV4 Intracellular Domain in Complex with Gtpase Rhoa (pdb code 9iqy). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Cryo-Em Structure of Human TRPV4 Intracellular Domain in Complex with Gtpase Rhoa, PDB code: 9iqy:

Magnesium binding site 1 out of 1 in the Cryo-Em Structure of Human TRPV4 Intracellular Domain in Complex with Gtpase Rhoa


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of Human TRPV4 Intracellular Domain in Complex with Gtpase Rhoa within 5.0Å range: probe atom residue distance (Å) B Occ J:Mg202 b:62.7 occ:1.00 O1B J:GDP201 2.1 69.7 1.0 O J:THR37 2.2 66.8 1.0 OG1 J:THR19 2.2 62.2 1.0 PB J:GDP201 3.0 69.7 1.0 C J:THR37 3.3 66.8 1.0 O2B J:GDP201 3.3 69.7 1.0 CB J:THR19 3.4 62.2 1.0 O3B J:GDP201 3.7 69.7 1.0 OD1 J:ASP59 4.1 58.1 1.0 N J:THR19 4.1 62.2 1.0 CA J:THR37 4.1 66.8 1.0 O J:PRO36 4.2 69.6 1.0 N J:VAL38 4.3 63.6 1.0 CA J:THR19 4.4 62.2 1.0 O3A J:GDP201 4.4 69.7 1.0 CG2 J:THR19 4.5 62.2 1.0 CA J:VAL38 4.5 63.6 1.0 OD2 J:ASP59 4.5 58.1 1.0 CE J:LYS18 4.5 62.3 1.0 CG J:ASP59 4.6 58.1 1.0 O J:THR60 4.7 58.8 1.0 OG1 J:THR37 4.7 66.8 1.0 NZ J:LYS18 4.8 62.3 1.0 CB J:ALA61 4.8 64.6 1.0 CB J:LYS18 4.8 62.3 1.0 CG1 J:VAL38 4.9 63.6 1.0 O1A J:GDP201 4.9 69.7 1.0 PA J:GDP201 5.0 69.7 1.0 O2A J:GDP201 5.0 69.7 1.0

J.W.Wang, Z.Yuan. Inactivation of Rhoa For Hypertension Treatment Through A TRPV4-Rhoa-RHOGDI1 Axis To Be Published.