Magnesium in PDB 9otn: Human Glutamine Synthetase Filament Bound to Atp

All present enzymatic activity of Human Glutamine Synthetase Filament Bound to Atp:
2.3.1.225; 6.3.1.2;

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 30; Page 4, Binding sites: 31 - 40;

Binding sites:

The binding sites of Magnesium atom in the Human Glutamine Synthetase Filament Bound to Atp (pdb code 9otn). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 40 binding sites of Magnesium where determined in the Human Glutamine Synthetase Filament Bound to Atp, PDB code: 9otn:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Magnesium binding site 1 out of 40 in the Human Glutamine Synthetase Filament Bound to Atp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human Glutamine Synthetase Filament Bound to Atp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg402 b:20.3 occ:1.00 OE2 A:GLU338 2.0 25.5 1.0 O3G A:ATP401 2.1 17.7 1.0 OE1 A:GLU134 2.3 21.8 1.0 O1B A:ATP401 2.4 20.0 1.0 OE2 A:GLU134 2.6 18.5 1.0 ND1 A:HIS253 2.7 14.4 1.0 CD A:GLU134 2.8 14.3 1.0 CD A:GLU338 3.1 20.6 1.0 PG A:ATP401 3.1 33.0 1.0 O3B A:ATP401 3.4 20.3 1.0 PB A:ATP401 3.4 17.9 1.0 O1G A:ATP401 3.5 18.3 1.0 OE1 A:GLU338 3.6 16.1 1.0 CG A:HIS253 3.6 13.8 1.0 CB A:HIS253 3.7 9.7 1.0 CE1 A:HIS253 3.7 13.6 1.0 NH1 A:ARG340 3.9 15.5 1.0 MG A:MG403 4.0 11.6 1.0 CG A:GLU134 4.3 8.8 1.0 CG A:GLU338 4.3 15.8 1.0 O3A A:ATP401 4.4 20.2 1.0 O2G A:ATP401 4.5 21.6 1.0 O2B A:ATP401 4.5 21.6 1.0 NH1 A:ARG324 4.6 24.8 1.0 O5' A:ATP401 4.6 20.8 1.0 O1A A:ATP401 4.7 16.7 1.0 CD2 A:HIS253 4.8 12.4 1.0 NE2 A:HIS253 4.8 15.7 1.0 CB A:GLU134 4.8 1.4 1.0 PA A:ATP401 4.9 17.4 1.0 CZ A:ARG340 5.0 19.9 1.0

Magnesium binding site 2 out of 40 in the Human Glutamine Synthetase Filament Bound to Atp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Human Glutamine Synthetase Filament Bound to Atp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg403 b:11.6 occ:1.00 O1A A:ATP401 2.0 16.7 1.0 O1G A:ATP401 2.0 18.3 1.0 OE2 A:GLU203 2.1 13.6 1.0 OE1 A:GLU134 2.3 21.8 1.0 O3B A:ATP401 2.9 20.3 1.0 PG A:ATP401 3.0 33.0 1.0 CD A:GLU203 3.1 16.0 1.0 CD A:GLU134 3.2 14.3 1.0 PA A:ATP401 3.3 17.4 1.0 OE1 A:GLU203 3.4 22.8 1.0 O3A A:ATP401 3.6 20.2 1.0 CG A:GLU134 3.7 8.8 1.0 PB A:ATP401 3.8 17.9 1.0 NE2 A:GLN205 3.8 3.9 1.0 O3G A:ATP401 3.9 17.7 1.0 MG A:MG402 4.0 20.3 1.0 OE2 A:GLU134 4.1 18.5 1.0 O1B A:ATP401 4.1 20.0 1.0 O2G A:ATP401 4.1 21.6 1.0 O5' A:ATP401 4.2 20.8 1.0 CB A:GLU134 4.3 1.4 1.0 CD A:GLN205 4.4 4.8 1.0 OD1 A:ASN194 4.4 13.2 1.0 O2A A:ATP401 4.4 21.4 1.0 CG A:GLN205 4.5 0.0 1.0 CG A:GLU203 4.5 8.5 1.0

Magnesium binding site 3 out of 40 in the Human Glutamine Synthetase Filament Bound to Atp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Human Glutamine Synthetase Filament Bound to Atp within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg402 b:21.4 occ:1.00 OE2 B:GLU338 1.9 24.1 1.0 O3G B:ATP401 2.1 25.1 1.0 OE1 B:GLU134 2.4 20.3 1.0 O1B B:ATP401 2.5 26.3 1.0 OE2 B:GLU134 2.6 19.4 1.0 ND1 B:HIS253 2.7 11.5 1.0 CD B:GLU134 2.8 11.5 1.0 CD B:GLU338 3.1 22.5 1.0 PG B:ATP401 3.2 32.7 1.0 O3B B:ATP401 3.2 18.8 1.0 PB B:ATP401 3.4 22.8 1.0 OE1 B:GLU338 3.6 20.9 1.0 CG B:HIS253 3.6 13.2 1.0 O2G B:ATP401 3.7 32.2 1.0 CE1 B:HIS253 3.7 15.7 1.0 CB B:HIS253 3.7 10.4 1.0 MG B:MG403 3.8 12.8 1.0 NH1 B:ARG340 4.0 17.6 1.0 CG B:GLU338 4.3 15.2 1.0 CG B:GLU134 4.3 10.5 1.0 O3A B:ATP401 4.4 12.8 1.0 O1G B:ATP401 4.5 28.8 1.0 O2B B:ATP401 4.5 23.9 1.0 O5' B:ATP401 4.6 21.8 1.0 NH1 B:ARG324 4.6 25.8 1.0 O1A B:ATP401 4.7 15.9 1.0 CD2 B:HIS253 4.8 13.2 1.0 NE2 B:HIS253 4.8 17.7 1.0 CB B:GLU134 4.8 2.9 1.0 PA B:ATP401 4.9 18.7 1.0

Magnesium binding site 4 out of 40 in the Human Glutamine Synthetase Filament Bound to Atp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Human Glutamine Synthetase Filament Bound to Atp within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg403 b:12.8 occ:1.00 OE1 B:GLU134 2.1 20.3 1.0 O1A B:ATP401 2.3 15.9 1.0 OE2 B:GLU203 2.4 14.2 1.0 O3B B:ATP401 2.8 18.8 1.0 CD B:GLU134 3.1 11.5 1.0 CD B:GLU203 3.3 15.1 1.0 O3G B:ATP401 3.3 25.1 1.0 PA B:ATP401 3.3 18.7 1.0 O3A B:ATP401 3.4 12.8 1.0 OE1 B:GLU203 3.4 19.0 1.0 PG B:ATP401 3.5 32.7 1.0 PB B:ATP401 3.7 22.8 1.0 O1G B:ATP401 3.7 28.8 1.0 MG B:MG402 3.8 21.4 1.0 CG B:GLU134 3.8 10.5 1.0 OE2 B:GLU134 3.9 19.4 1.0 O1B B:ATP401 4.0 26.3 1.0 NE2 B:GLN205 4.1 5.3 1.0 O5' B:ATP401 4.2 21.8 1.0 CB B:GLU134 4.3 2.9 1.0 O2A B:ATP401 4.5 19.7 1.0 OD1 B:ASN194 4.6 11.0 1.0 CD B:GLN205 4.7 3.1 1.0 CG B:GLN205 4.7 0.5 1.0 CG B:GLU203 4.7 10.4 1.0 O2G B:ATP401 4.9 32.2 1.0

Magnesium binding site 5 out of 40 in the Human Glutamine Synthetase Filament Bound to Atp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of Human Glutamine Synthetase Filament Bound to Atp within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg402 b:22.7 occ:1.00 OE2 C:GLU338 1.9 21.6 1.0 O3G C:ATP401 2.1 15.8 1.0 O1B C:ATP401 2.3 21.0 1.0 OE1 C:GLU134 2.4 21.3 1.0 OE2 C:GLU134 2.7 21.8 1.0 CD2 C:HIS253 2.8 11.2 1.0 CD C:GLU134 2.9 13.1 1.0 CD C:GLU338 3.1 18.1 1.0 PG C:ATP401 3.2 29.6 1.0 O3B C:ATP401 3.2 22.1 1.0 PB C:ATP401 3.3 18.7 1.0 OE1 C:GLU338 3.6 17.0 1.0 O2G C:ATP401 3.6 18.2 1.0 CG C:HIS253 3.6 12.8 1.0 CB C:HIS253 3.8 12.5 1.0 MG C:MG403 3.8 12.0 1.0 NH1 C:ARG340 3.9 17.5 1.0 NE2 C:HIS253 3.9 12.6 1.0 CG C:GLU338 4.3 14.3 1.0 O2B C:ATP401 4.3 20.6 1.0 O3A C:ATP401 4.4 14.4 1.0 CG C:GLU134 4.4 12.0 1.0 NH1 C:ARG324 4.4 25.0 1.0 O1G C:ATP401 4.5 23.3 1.0 O2A C:ATP401 4.5 16.3 1.0 O5' C:ATP401 4.7 21.4 1.0 ND1 C:HIS253 4.8 11.8 1.0 PA C:ATP401 4.9 21.3 1.0 CZ C:ARG340 4.9 20.9 1.0 CB C:GLU134 5.0 4.5 1.0 CE1 C:HIS253 5.0 15.8 1.0

Magnesium binding site 6 out of 40 in the Human Glutamine Synthetase Filament Bound to Atp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 6 of Human Glutamine Synthetase Filament Bound to Atp within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg403 b:12.0 occ:1.00 O2A C:ATP401 2.0 16.3 1.0 O2G C:ATP401 2.0 18.2 1.0 OE1 C:GLU134 2.2 21.3 1.0 OE2 C:GLU203 2.3 16.9 1.0 O3B C:ATP401 2.7 22.1 1.0 PG C:ATP401 2.9 29.6 1.0 CD C:GLU134 3.1 13.1 1.0 CD C:GLU203 3.2 16.0 1.0 PA C:ATP401 3.4 21.3 1.0 OE1 C:GLU203 3.4 22.0 1.0 O3A C:ATP401 3.7 14.4 1.0 PB C:ATP401 3.7 18.7 1.0 CG C:GLU134 3.7 12.0 1.0 O3G C:ATP401 3.7 15.8 1.0 MG C:MG402 3.8 22.7 1.0 OE2 C:GLU134 4.0 21.8 1.0 O1B C:ATP401 4.0 21.0 1.0 NE2 C:GLN205 4.1 2.8 1.0 O1G C:ATP401 4.1 23.3 1.0 O5' C:ATP401 4.1 21.4 1.0 CB C:GLU134 4.2 4.5 1.0 O1A C:ATP401 4.4 22.5 1.0 CG C:GLN205 4.5 1.6 1.0 CD C:GLN205 4.6 1.4 1.0 CG C:GLU203 4.6 9.9 1.0 OD1 C:ASN194 4.6 14.1 1.0

Magnesium binding site 7 out of 40 in the Human Glutamine Synthetase Filament Bound to Atp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 7 of Human Glutamine Synthetase Filament Bound to Atp within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg402 b:23.4 occ:1.00 OE2 D:GLU338 1.9 24.7 1.0 O2G D:ATP401 2.2 19.7 1.0 OE1 D:GLU134 2.3 18.7 1.0 OE2 D:GLU134 2.7 22.8 1.0 ND1 D:HIS253 2.7 14.4 1.0 CD D:GLU134 2.8 12.6 1.0 O3B D:ATP401 3.0 14.4 1.0 PG D:ATP401 3.1 30.8 1.0 CD D:GLU338 3.1 20.9 1.0 O3G D:ATP401 3.5 15.1 1.0 CG D:HIS253 3.6 14.7 1.0 CB D:HIS253 3.6 11.7 1.0 OE1 D:GLU338 3.7 19.3 1.0 CE1 D:HIS253 3.7 13.7 1.0 NH1 D:ARG340 3.9 19.3 1.0 O3A D:ATP401 3.9 16.1 1.0 PB D:ATP401 4.2 28.6 1.0 MG D:MG403 4.2 15.7 1.0 CG D:GLU338 4.3 17.0 1.0 CG D:GLU134 4.3 10.7 1.0 O1G D:ATP401 4.4 20.1 1.0 NH1 D:ARG324 4.7 27.1 1.0 CD2 D:HIS253 4.8 13.2 1.0 O2B D:ATP401 4.8 26.1 1.0 NE2 D:HIS253 4.8 16.6 1.0 CB D:GLU134 4.8 3.6 1.0 PA D:ATP401 4.9 15.8 1.0 O5' D:ATP401 4.9 22.9 1.0 O1A D:ATP401 4.9 16.8 1.0 CZ D:ARG340 5.0 22.4 1.0

Magnesium binding site 8 out of 40 in the Human Glutamine Synthetase Filament Bound to Atp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 8 of Human Glutamine Synthetase Filament Bound to Atp within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg403 b:15.7 occ:1.00 O3G D:ATP401 1.9 15.1 1.0 O1A D:ATP401 2.0 16.8 1.0 OE2 D:GLU203 2.1 12.4 1.0 OE1 D:GLU134 2.5 18.7 1.0 CD D:GLU203 3.1 14.2 1.0 PA D:ATP401 3.2 15.8 1.0 CD D:GLU134 3.3 12.6 1.0 PG D:ATP401 3.3 30.8 1.0 OE1 D:GLU203 3.4 18.7 1.0 O3A D:ATP401 3.5 16.1 1.0 NE2 D:GLN205 3.6 2.1 1.0 O3B D:ATP401 3.6 14.4 1.0 CG D:GLU134 3.7 10.7 1.0 PB D:ATP401 3.9 28.6 1.0 O1B D:ATP401 4.0 30.0 1.0 O5' D:ATP401 4.1 22.9 1.0 O2G D:ATP401 4.1 19.7 1.0 CB D:GLU134 4.2 3.6 1.0 CD D:GLN205 4.2 4.2 1.0 MG D:MG402 4.2 23.4 1.0 CG D:GLN205 4.3 3.0 1.0 OE2 D:GLU134 4.3 22.8 1.0 OD1 D:ASN194 4.3 11.2 1.0 O1G D:ATP401 4.4 20.1 1.0 O2A D:ATP401 4.4 21.3 1.0 CG D:GLU203 4.4 9.9 1.0

Magnesium binding site 9 out of 40 in the Human Glutamine Synthetase Filament Bound to Atp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 9 of Human Glutamine Synthetase Filament Bound to Atp within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg402 b:21.2 occ:1.00 OE2 E:GLU338 2.0 26.5 1.0 O2G E:ATP401 2.0 16.0 1.0 O2B E:ATP401 2.2 19.8 1.0 OE1 E:GLU134 2.5 20.4 1.0 OE2 E:GLU134 2.6 19.9 1.0 ND1 E:HIS253 2.9 14.4 1.0 CD E:GLU134 2.9 13.0 1.0 CD E:GLU338 3.0 20.2 1.0 PG E:ATP401 3.1 26.9 1.0 O3B E:ATP401 3.4 19.9 1.0 PB E:ATP401 3.4 20.1 1.0 OE1 E:GLU338 3.5 17.9 1.0 O1G E:ATP401 3.6 17.3 1.0 CG E:HIS253 3.8 14.5 1.0 NH1 E:ARG340 3.8 18.6 1.0 MG E:MG403 3.8 10.9 1.0 CE1 E:HIS253 3.8 14.4 1.0 CB E:HIS253 3.9 10.2 1.0 CG E:GLU338 4.3 15.9 1.0 NH1 E:ARG324 4.3 26.7 1.0 CG E:GLU134 4.4 10.3 1.0 O3A E:ATP401 4.4 18.4 1.0 O1B E:ATP401 4.4 25.9 1.0 O3G E:ATP401 4.4 22.0 1.0 O1A E:ATP401 4.5 13.8 1.0 O5' E:ATP401 4.6 21.9 1.0 PA E:ATP401 4.8 18.4 1.0 CZ E:ARG340 4.9 21.7 1.0 CD2 E:HIS253 5.0 14.2 1.0 NE2 E:HIS253 5.0 17.4 1.0

Magnesium binding site 10 out of 40 in the Human Glutamine Synthetase Filament Bound to Atp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 10 of Human Glutamine Synthetase Filament Bound to Atp within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg403 b:10.9 occ:1.00 O1G E:ATP401 2.0 17.3 1.0 O1A E:ATP401 2.0 13.8 1.0 OE1 E:GLU134 2.1 20.4 1.0 OE2 E:GLU203 2.4 13.3 1.0 O3B E:ATP401 2.8 19.9 1.0 PG E:ATP401 2.9 26.9 1.0 CD E:GLU134 3.0 13.0 1.0 PA E:ATP401 3.3 18.4 1.0 CD E:GLU203 3.3 13.8 1.0 OE1 E:GLU203 3.5 18.6 1.0 O3A E:ATP401 3.6 18.4 1.0 O2G E:ATP401 3.7 16.0 1.0 CG E:GLU134 3.7 10.3 1.0 PB E:ATP401 3.7 20.1 1.0 MG E:MG402 3.8 21.2 1.0 O2B E:ATP401 3.9 19.8 1.0 OE2 E:GLU134 3.9 19.9 1.0 NE2 E:GLN205 4.0 2.4 1.0 O3G E:ATP401 4.1 22.0 1.0 O5' E:ATP401 4.2 21.9 1.0 CB E:GLU134 4.2 2.8 1.0 O2A E:ATP401 4.4 20.9 1.0 CD E:GLN205 4.5 4.0 1.0 CG E:GLN205 4.5 2.5 1.0 CG E:GLU203 4.7 10.8 1.0 OD1 E:ASN194 4.8 13.9 1.0

E.R.Greene, R.S.Muniz, H.Yamamura, S.Hoff, P.Bajaj, D.J.Lee, E.M.Thompson, A.Arada, M.Bonomi, J.M.Kollman, J.S.Fraser. Product-Stabilized Filamentation By Human Glutamine Synthetase Allosterically Tunes Metabolic Activity To Be Published.