Atomistry » Magnesium » PDB 1bho-1c5p » 1c1p
Atomistry »
  Magnesium »
    PDB 1bho-1c5p »
      1c1p »

Magnesium in PDB 1c1p: Recruiting Zinc to Mediate Potent, Specific Inhibition of Serine Proteases

Enzymatic activity of Recruiting Zinc to Mediate Potent, Specific Inhibition of Serine Proteases

All present enzymatic activity of Recruiting Zinc to Mediate Potent, Specific Inhibition of Serine Proteases:
3.4.21.4;

Protein crystallography data

The structure of Recruiting Zinc to Mediate Potent, Specific Inhibition of Serine Proteases, PDB code: 1c1p was solved by B.A.Katz, C.Luong, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 7.50 / 1.37
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 54.860, 54.860, 109.790, 90.00, 90.00, 120.00
R / Rfree (%) 17.8 / 19.2

Other elements in 1c1p:

The structure of Recruiting Zinc to Mediate Potent, Specific Inhibition of Serine Proteases also contains other interesting chemical elements:

Calcium (Ca) 1 atom

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Recruiting Zinc to Mediate Potent, Specific Inhibition of Serine Proteases (pdb code 1c1p). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Recruiting Zinc to Mediate Potent, Specific Inhibition of Serine Proteases, PDB code: 1c1p:

Magnesium binding site 1 out of 1 in 1c1p

Go back to Magnesium Binding Sites List in 1c1p
Magnesium binding site 1 out of 1 in the Recruiting Zinc to Mediate Potent, Specific Inhibition of Serine Proteases


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Recruiting Zinc to Mediate Potent, Specific Inhibition of Serine Proteases within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg263

b:19.2
occ:1.00
 HA3 A:GLY197 2.3 9.8 1.0
H2 A:HOH250 2.6 14.1 1.0
O A:SER139 2.7 12.4 1.0
HA3 A:GLY43 2.7 9.8 1.0
HA3 A:GLY140 2.7 11.2 1.0
O A:ASP194 2.9 11.5 1.0
HA2 A:GLY140 3.0 11.2 1.0
HA A:ASP194 3.0 12.9 1.0
O A:HOH250 3.0 14.6 1.0
OE1 A:GLN30 3.2 16.9 1.0
CA A:GLY197 3.3 10.0 1.0
CA A:GLY140 3.3 11.2 1.0
HD2 A:PRO198 3.4 11.0 1.0
HE21 A:GLN30 3.4 13.7 1.0
H1 A:HOH250 3.5 12.1 1.0
H A:GLY197 3.5 9.7 1.0
HA2 A:GLY197 3.5 8.9 1.0
HB3 A:ASP194 3.7 12.1 1.0
C A:ASP194 3.7 12.3 1.0
C A:SER139 3.7 12.4 1.0
N A:GLY197 3.7 10.4 1.0
CA A:ASP194 3.7 12.6 1.0
CA A:GLY43 3.8 9.9 1.0
H A:TRP141 4.0 11.6 1.0
N A:GLY140 4.0 11.2 1.0
CD A:GLN30 4.0 14.0 1.0
NE2 A:GLN30 4.1 12.1 1.0
HG23 A:VAL213 4.1 13.2 1.0
H A:GLY43 4.2 9.1 1.0
CB A:ASP194 4.2 12.5 1.0
CD A:PRO198 4.2 12.6 1.0
HA2 A:GLY43 4.3 10.4 1.0
N A:GLY43 4.3 9.7 1.0
HD3 A:PRO198 4.3 11.7 1.0
C A:GLY197 4.4 11.3 1.0
OD2 A:ASP194 4.4 12.2 1.0
C A:GLY140 4.6 11.5 1.0
H A:GLY44 4.7 11.1 1.0
N A:TRP141 4.7 11.8 1.0
C A:GLY43 4.7 10.4 1.0
N A:PRO198 4.7 12.1 1.0
O A:SER195 4.8 10.3 1.0
O A:GLY193 4.8 13.0 1.0
HE3 A:TRP141 4.8 12.2 1.0
CG A:ASP194 4.8 11.9 1.0
HG21 A:VAL213 4.9 13.2 1.0
N A:SER195 4.9 12.3 1.0
H A:SER139 4.9 10.6 1.0
C A:GLY196 4.9 10.7 1.0
CG2 A:VAL213 4.9 11.9 1.0
HB A:VAL213 5.0 11.3 1.0
HE22 A:GLN30 5.0 13.1 1.0
N A:GLY44 5.0 11.4 1.0
H A:GLY140 5.0 11.2 1.0
HD13 A:LEU155 5.0 13.6 1.0

Reference:

B.A.Katz, J.M.Clark, J.S.Finer-Moore, T.E.Jenkins, C.R.Johnson, M.J.Ross, C.Luong, W.R.Moore, R.M.Stroud. Design of Potent Selective Zinc-Mediated Serine Protease Inhibitors. Nature V. 391 608 1998.
ISSN: ISSN 0028-0836
PubMed: 9468142
DOI: 10.1038/35422
Page generated: Tue Aug 13 02:17:12 2024

Last articles

Cl in 2QS7
Cl in 2QSA
Cl in 2QS3
Cl in 2QS2
Cl in 2QS1
Cl in 2QNQ
Cl in 2QRR
Cl in 2QRJ
Cl in 2QPM
Cl in 2QP6
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy