Magnesium in PDB 1i57: Crystal Structure of Apo Human PTP1B (C215S) Mutant

All present enzymatic activity of Crystal Structure of Apo Human PTP1B (C215S) Mutant:
3.1.3.48;

The structure of Crystal Structure of Apo Human PTP1B (C215S) Mutant, PDB code: 1i57 was solved by G.Scapin, S.Patel, V.Patel, B.Kennedy, E.Asante-Appiah, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.10
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	87.381, 87.381, 95.942, 90.00, 90.00, 120.00
R / Rfree (%)	19.5 / 26.6

The structure of Crystal Structure of Apo Human PTP1B (C215S) Mutant also contains other interesting chemical elements:

Chlorine

(Cl)

5 atoms

The binding sites of Magnesium atom in the Crystal Structure of Apo Human PTP1B (C215S) Mutant (pdb code 1i57). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Apo Human PTP1B (C215S) Mutant, PDB code: 1i57:

Magnesium binding site 1 out of 1 in the Crystal Structure of Apo Human PTP1B (C215S) Mutant


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Apo Human PTP1B (C215S) Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg401 b:47.7 occ:1.00 O A:HOH1231 1.9 46.0 1.0 O A:HOH1082 2.1 35.6 1.0 O A:HOH1076 2.1 27.7 1.0 O A:HOH1211 2.2 58.9 1.0 O A:HOH1027 2.5 38.7 1.0 O A:HOH1072 2.7 30.0 1.0 OE1 A:GLU130 4.1 30.8 1.0 OE1 A:GLU129 4.2 31.8 1.0 OE2 A:GLU130 4.5 50.9 1.0 CD A:GLU130 4.8 23.1 1.0 CG A:LYS128 4.9 38.0 1.0

G.Scapin, S.Patel, V.Patel, B.Kennedy, E.Asante-Appiah. The Structure of Apo Protein-Tyrosine Phosphatase 1B C215S Mutant: More Than Just An S --> O Change. Protein Sci. V. 10 1596 2001.
ISSN: ISSN 0961-8368
PubMed: 11468356
DOI: 10.1110/PS.11001