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Atomistry » Magnesium » PDB 1ofh-1oyj » 1oi9 » |
Magnesium in PDB 1oi9: Structure of Human THR160-Phospho CDK2/Cyclin A Complexed with A 6-Cyclohexylmethyloxy-2-Anilino-Purine InhibitorEnzymatic activity of Structure of Human THR160-Phospho CDK2/Cyclin A Complexed with A 6-Cyclohexylmethyloxy-2-Anilino-Purine Inhibitor
All present enzymatic activity of Structure of Human THR160-Phospho CDK2/Cyclin A Complexed with A 6-Cyclohexylmethyloxy-2-Anilino-Purine Inhibitor:
2.7.1.37; Protein crystallography data
The structure of Structure of Human THR160-Phospho CDK2/Cyclin A Complexed with A 6-Cyclohexylmethyloxy-2-Anilino-Purine Inhibitor, PDB code: 1oi9
was solved by
D.J.Pratt,
J.A.Endicott,
M.E.M.Noble,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Structure of Human THR160-Phospho CDK2/Cyclin A Complexed with A 6-Cyclohexylmethyloxy-2-Anilino-Purine Inhibitor
(pdb code 1oi9). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structure of Human THR160-Phospho CDK2/Cyclin A Complexed with A 6-Cyclohexylmethyloxy-2-Anilino-Purine Inhibitor, PDB code: 1oi9: Magnesium binding site 1 out of 1 in 1oi9Go back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Structure of Human THR160-Phospho CDK2/Cyclin A Complexed with A 6-Cyclohexylmethyloxy-2-Anilino-Purine Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
I.R.Hardcastle,
C.E.Arris,
J.Bentley,
F.T.Boyle,
Y.Chen,
N.J.Curtin,
J.A.Endicott,
A.E.Gibson,
B.T.Golding,
R.J.Griffin,
P.Jewsbury,
J.Menyerol,
V.Mesguiche,
D.R.Newell,
M.E.M.Noble,
D.J.Pratt,
L.-Z.Wang,
H.J.Whitfield.
N2-Substituted O6-Cyclohexylmethylguanine Derivatives: Potent Inhibitors of Cyclin-Dependent Kinases 1 and 2 J.Med.Chem. V. 47 3710 2004.
Page generated: Tue Aug 13 10:39:17 2024
ISSN: ISSN 0022-2623 PubMed: 15239650 DOI: 10.1021/JM0311442 |
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