Magnesium in PDB 1ol7: Structure of Human Aurora-A 122-403 Phosphorylated on THR287, THR288

All present enzymatic activity of Structure of Human Aurora-A 122-403 Phosphorylated on THR287, THR288:
2.7.1.37;

The structure of Structure of Human Aurora-A 122-403 Phosphorylated on THR287, THR288, PDB code: 1ol7 was solved by R.Bayliss, E.Conti, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20 / 2.75
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	81.180, 81.180, 169.620, 90.00, 90.00, 120.00
R / Rfree (%)	25.7 / 29.6

The binding sites of Magnesium atom in the Structure of Human Aurora-A 122-403 Phosphorylated on THR287, THR288 (pdb code 1ol7). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of Human Aurora-A 122-403 Phosphorylated on THR287, THR288, PDB code: 1ol7:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Structure of Human Aurora-A 122-403 Phosphorylated on THR287, THR288


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Human Aurora-A 122-403 Phosphorylated on THR287, THR288 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1392 b:47.2 occ:1.00 O3A A:ADP531 2.1 62.8 1.0 OD1 A:ASN261 2.1 41.7 1.0 OD2 A:ASP274 2.9 52.1 1.0 O2A A:ADP531 3.0 54.1 1.0 PB A:ADP531 3.0 34.8 1.0 O3B A:ADP531 3.1 53.8 1.0 PA A:ADP531 3.1 35.2 1.0 CG A:ASN261 3.2 36.5 1.0 CG A:ASP274 3.5 42.1 1.0 O2B A:ADP531 3.5 48.4 1.0 C5' A:ADP531 3.6 61.7 1.0 ND2 A:ASN261 3.7 30.8 1.0 O5' A:ADP531 3.9 48.3 1.0 CB A:ASP274 4.0 51.0 1.0 MG A:MG1393 4.1 52.1 1.0 O1B A:ADP531 4.2 50.8 1.0 OD1 A:ASP274 4.3 54.3 1.0 O1A A:ADP531 4.4 33.7 1.0 CB A:ASN261 4.5 36.4 1.0 O3' A:ADP531 4.5 46.2 1.0 C4' A:ADP531 4.6 46.5 1.0 C3' A:ADP531 4.6 37.5 1.0 CB A:GLU260 4.8 50.8 1.0 CA A:ASN261 4.8 38.9 1.0 N A:ASN261 4.8 40.1 1.0 C A:GLU260 4.9 39.1 1.0 O A:GLU260 4.9 44.8 1.0

Magnesium binding site 2 out of 2 in the Structure of Human Aurora-A 122-403 Phosphorylated on THR287, THR288


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of Human Aurora-A 122-403 Phosphorylated on THR287, THR288 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1393 b:52.1 occ:1.00 O2B A:ADP531 2.1 48.4 1.0 OD2 A:ASP274 2.2 52.1 1.0 OD1 A:ASP274 2.5 54.3 1.0 CG A:ASP274 2.7 42.1 1.0 PB A:ADP531 3.5 34.8 1.0 OD2 A:ASP256 3.8 39.2 1.0 O3A A:ADP531 3.9 62.8 1.0 MG A:MG1392 4.1 47.2 1.0 CB A:ASP274 4.1 51.0 1.0 O3B A:ADP531 4.2 53.8 1.0 O A:HOH2002 4.3 40.4 1.0 CA A:GLY276 4.4 37.8 1.0 CD1 A:TRP277 4.5 54.3 1.0 O1B A:ADP531 4.6 50.8 1.0 N A:GLY276 4.6 42.9 1.0 O A:ASP274 4.7 53.9 1.0 OD1 A:ASN261 4.8 41.7 1.0 NE1 A:TRP277 4.9 59.9 1.0 NZ A:LYS162 4.9 33.0 1.0 ND2 A:ASN261 5.0 30.8 1.0 C A:ASP274 5.0 51.4 1.0

R.Bayliss, T.Sardon, I.Vernos, E.Conti. Structural Basis of Aurora-A Activation By TPX2 at the Mitotic Spindle Mol.Cell V. 12 851 2003.
ISSN: ISSN 1097-2765
PubMed: 14580337
DOI: 10.1016/S1097-2765(03)00392-7