Magnesium in PDB 1ubw: Structure of Farnesyl Pyrophosphate Synthetase

All present enzymatic activity of Structure of Farnesyl Pyrophosphate Synthetase:
2.5.1.1;

The structure of Structure of Farnesyl Pyrophosphate Synthetase, PDB code: 1ubw was solved by L.C.Tarshis, P.Proteau, C.D.Poulter, J.C.Sacchettini, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	N/A / 2.50
Space group	I 41 2 2
Cell size a, b, c (Å), α, β, γ (°)	88.700, 88.700, 274.900, 90.00, 90.00, 90.00
R / Rfree (%)	19.2 / n/a

The binding sites of Magnesium atom in the Structure of Farnesyl Pyrophosphate Synthetase (pdb code 1ubw). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of Farnesyl Pyrophosphate Synthetase, PDB code: 1ubw:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Structure of Farnesyl Pyrophosphate Synthetase


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Farnesyl Pyrophosphate Synthetase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg402 b:30.2 occ:1.00 OD2 A:ASP117 2.0 31.3 1.0 O3A A:GPP401 2.2 50.9 1.0 OD2 A:ASP121 2.2 31.4 1.0 O A:HOH463 2.5 34.7 1.0 O2B A:GPP401 2.8 39.0 1.0 O1A A:GPP401 2.9 46.8 1.0 CG A:ASP117 3.0 25.4 1.0 PA A:GPP401 3.1 51.7 1.0 CG A:ASP121 3.3 36.8 1.0 PB A:GPP401 3.3 45.2 1.0 OD1 A:ASP117 3.4 21.9 1.0 O1 A:GPP401 3.7 52.6 1.0 MG A:MG403 3.8 38.2 1.0 CB A:ASP121 3.8 29.9 1.0 O3B A:GPP401 4.0 56.8 1.0 CB A:ASP117 4.2 11.0 1.0 O2A A:GPP401 4.4 33.0 1.0 OD1 A:ASP121 4.4 44.5 1.0 NZ A:LYS280 4.4 88.6 1.0 OG A:SER123 4.6 28.9 1.0 C A:ASP117 4.7 21.0 1.0 O A:ASP117 4.7 15.1 1.0 O1B A:GPP401 4.8 60.2 1.0 OD1 A:ASP118 4.9 25.9 1.0 CA A:ASP117 5.0 18.0 1.0 O A:HOH462 5.0 47.7 1.0

Magnesium binding site 2 out of 2 in the Structure of Farnesyl Pyrophosphate Synthetase


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of Farnesyl Pyrophosphate Synthetase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg403 b:38.2 occ:1.00 O1A A:GPP401 2.0 46.8 1.0 OD1 A:ASP117 2.3 21.9 1.0 OD2 A:ASP121 2.7 31.4 1.0 O A:HOH490 2.9 48.3 1.0 OD2 A:ASP188 3.3 44.8 1.0 CG A:ASP117 3.3 25.4 1.0 CG A:ASP121 3.5 36.8 1.0 OD1 A:ASP121 3.5 44.5 1.0 PA A:GPP401 3.6 51.7 1.0 MG A:MG402 3.8 30.2 1.0 OD2 A:ASP117 3.8 31.3 1.0 OE1 A:GLN185 4.0 17.9 1.0 O1 A:GPP401 4.1 52.6 1.0 O3A A:GPP401 4.4 50.9 1.0 NE2 A:GLN185 4.4 26.8 1.0 CG A:ASP188 4.4 29.0 1.0 CD A:GLN185 4.6 11.5 1.0 CD1 A:LEU189 4.6 23.5 1.0 O2A A:GPP401 4.6 33.0 1.0 CB A:ASP117 4.6 11.0 1.0 O A:HOH464 4.9 38.0 1.0 CB A:ASP121 4.9 29.9 1.0 CB A:ASP188 5.0 17.6 1.0 C2 A:GPP401 5.0 48.2 1.0

L.C.Tarshis, P.J.Proteau, B.A.Kellogg, J.C.Sacchettini, C.D.Poulter. Regulation of Product Chain Length By Isoprenyl Diphosphate Synthases. Proc.Natl.Acad.Sci.Usa V. 93 15018 1996.
ISSN: ISSN 0027-8424
PubMed: 8986756
DOI: 10.1073/PNAS.93.26.15018