Atomistry » Magnesium » PDB 2bhd-2bt1 » 2bsl
Atomistry »
  Magnesium »
    PDB 2bhd-2bt1 »
      2bsl »

Magnesium in PDB 2bsl: Crystal Structure of L. Lactis Dihydroorotate Dehydrogense A in Complex with 3,4-Dihydroxybenzoate

Enzymatic activity of Crystal Structure of L. Lactis Dihydroorotate Dehydrogense A in Complex with 3,4-Dihydroxybenzoate

All present enzymatic activity of Crystal Structure of L. Lactis Dihydroorotate Dehydrogense A in Complex with 3,4-Dihydroxybenzoate:
1.3.99.11;

Protein crystallography data

The structure of Crystal Structure of L. Lactis Dihydroorotate Dehydrogense A in Complex with 3,4-Dihydroxybenzoate, PDB code: 2bsl was solved by A.E.Wolfe, M.Hansen, S.G.Gattis, Y.-C.Hu, E.Johansson, S.Arent, S.Larsen, B.A.Palfey, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 25.00 / 2.30
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 53.588, 108.160, 66.222, 90.00, 104.06, 90.00
R / Rfree (%) 18.6 / 24.1

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Crystal Structure of L. Lactis Dihydroorotate Dehydrogense A in Complex with 3,4-Dihydroxybenzoate (pdb code 2bsl). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of L. Lactis Dihydroorotate Dehydrogense A in Complex with 3,4-Dihydroxybenzoate, PDB code: 2bsl:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in 2bsl

Go back to Magnesium Binding Sites List in 2bsl
Magnesium binding site 1 out of 2 in the Crystal Structure of L. Lactis Dihydroorotate Dehydrogense A in Complex with 3,4-Dihydroxybenzoate


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of L. Lactis Dihydroorotate Dehydrogense A in Complex with 3,4-Dihydroxybenzoate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1314

b:37.1
occ:1.00
O A:LYS33 2.3 36.2 1.0
O A:SER35 2.4 35.5 1.0
O A:HOH2013 2.6 33.4 1.0
C A:LYS33 3.5 36.7 1.0
C A:SER35 3.6 36.4 1.0
C A:ALA34 3.9 37.0 1.0
O A:ALA34 4.1 37.1 1.0
O A:ALA37 4.1 32.5 1.0
N A:SER35 4.1 37.2 1.0
O A:HOH2008 4.2 26.2 1.0
O A:LEU32 4.2 36.0 1.0
CA A:ALA34 4.4 36.7 1.0
N A:ALA34 4.4 36.2 1.0
CA A:LYS33 4.4 37.1 1.0
CA A:SER35 4.5 37.3 1.0
N A:GLN36 4.5 36.7 1.0
CA A:GLN36 4.5 35.7 1.0
O A:HOH2007 4.6 26.4 1.0
C A:GLN36 4.8 34.5 1.0
N A:ALA37 4.9 33.0 1.0

Magnesium binding site 2 out of 2 in 2bsl

Go back to Magnesium Binding Sites List in 2bsl
Magnesium binding site 2 out of 2 in the Crystal Structure of L. Lactis Dihydroorotate Dehydrogense A in Complex with 3,4-Dihydroxybenzoate


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of L. Lactis Dihydroorotate Dehydrogense A in Complex with 3,4-Dihydroxybenzoate within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mg1314

b:38.6
occ:1.00
O B:LYS33 2.3 36.4 1.0
O B:SER35 2.4 36.0 1.0
O B:HOH2013 2.5 29.5 1.0
O B:HOH2014 2.6 28.9 1.0
C B:LYS33 3.4 36.6 1.0
C B:SER35 3.7 36.6 1.0
O B:ALA37 4.0 33.1 1.0
C B:ALA34 4.1 37.1 1.0
O B:HOH2011 4.1 50.4 1.0
O B:HOH2006 4.1 35.3 1.0
O B:HOH2005 4.2 29.9 1.0
O B:LEU32 4.2 37.0 1.0
O B:ALA34 4.2 37.0 1.0
CA B:LYS33 4.2 37.3 1.0
N B:SER35 4.3 37.1 1.0
O B:HOH2031 4.3 40.7 1.0
N B:ALA34 4.4 36.5 1.0
CA B:ALA34 4.5 36.4 1.0
CA B:SER35 4.6 37.3 1.0
N B:GLN36 4.6 36.5 1.0
CA B:GLN36 4.7 36.1 1.0
C B:GLN36 4.8 34.8 1.0
N B:ALA37 5.0 33.5 1.0

Reference:

A.E.Wolfe, M.Thymark, S.G.Gattis, R.L.Fagan, Y.-C.Hu, E.Johansson, S.Arent, S.Larsen, B.A.Palfey. Interaction of Benzoate Pyrimidine Analogues with Class 1A Dihydroorotate Dehydrogenase From Lactococcus Lactis. Biochemistry V. 46 5741 2007.
ISSN: ISSN 0006-2960
PubMed: 17444658
DOI: 10.1021/BI7001554
Page generated: Tue Aug 13 22:00:43 2024

Last articles

Cl in 8B5P
Cl in 8B2Y
Cl in 8B4X
Cl in 8B4W
Cl in 8B4V
Cl in 8B4U
Cl in 8B3V
Cl in 8B4Q
Cl in 8B46
Cl in 8B3U
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy