Magnesium in PDB 2cbz: Structure of the Human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1

The structure of Structure of the Human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1, PDB code: 2cbz was solved by O.Ramaen, N.Leulliot, C.Sizun, N.Ulryck, O.Pamlard, J.-Y.Lallemand, H.Van Tilbeurgh, E.Jacquet, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 1.5
Space group	P 31
Cell size a, b, c (Å), α, β, γ (°)	65.560, 65.560, 64.612, 90.00, 90.00, 120.00
R / Rfree (%)	16 / 18.7

The binding sites of Magnesium atom in the Structure of the Human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1 (pdb code 2cbz). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structure of the Human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1, PDB code: 2cbz:

Magnesium binding site 1 out of 1 in the Structure of the Human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of the Human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1872 b:9.1 occ:1.00 O1G A:ATP1873 2.0 8.1 1.0 O A:HOH2188 2.1 7.7 1.0 OG A:SER685 2.1 7.1 1.0 O2B A:ATP1873 2.1 8.5 1.0 OE1 A:GLN713 2.1 7.5 1.0 O A:HOH2280 2.1 7.8 1.0 CD A:GLN713 3.1 8.4 1.0 CB A:SER685 3.2 8.1 1.0 PG A:ATP1873 3.2 9.8 1.0 PB A:ATP1873 3.2 9.4 1.0 O3B A:ATP1873 3.4 9.3 1.0 NE2 A:GLN713 3.4 9.5 1.0 N A:SER685 3.9 7.7 1.0 O A:HOH2110 3.9 26.1 1.0 O A:HOH2275 4.0 19.4 1.0 O1A A:ATP1873 4.0 10.2 1.0 OD1 A:ASP792 4.1 9.1 1.0 CA A:SER685 4.1 8.2 1.0 OD2 A:ASP792 4.2 8.9 1.0 O3G A:ATP1873 4.2 10.1 1.0 O2G A:ATP1873 4.2 9.7 1.0 O3A A:ATP1873 4.3 9.1 1.0 O A:HOH2191 4.3 9.6 1.0 O1B A:ATP1873 4.3 8.2 1.0 CG A:GLN713 4.4 8.3 1.0 CG A:ASP792 4.5 8.8 1.0 PA A:ATP1873 4.7 10.0 1.0 CB A:GLN713 4.7 8.1 1.0 CB A:LYS684 5.0 8.0 1.0

O.Ramaen, N.Leulliot, C.Sizun, N.Ulryck, O.Pamlard, J.-Y.Lallemand, H.Van Tilbeurgh, E.Jacquet. Structure of the Human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1 Bound to Mg(2+)/Atp Reveals A Non-Productive Catalytic Site. J.Mol.Biol. V. 359 940 2006.
ISSN: ISSN 0022-2836
PubMed: 16697012
DOI: 10.1016/J.JMB.2006.04.005