Atomistry » Magnesium » PDB 2iw4-2j5x » 2izs
Atomistry »
  Magnesium »
    PDB 2iw4-2j5x »
      2izs »

Magnesium in PDB 2izs: Structure of Casein Kinase Gamma 3 in Complex with Inhibitor

Enzymatic activity of Structure of Casein Kinase Gamma 3 in Complex with Inhibitor

All present enzymatic activity of Structure of Casein Kinase Gamma 3 in Complex with Inhibitor:
2.7.11.1;

Protein crystallography data

The structure of Structure of Casein Kinase Gamma 3 in Complex with Inhibitor, PDB code: 2izs was solved by G.Bunkoczi, E.Salah, P.Rellos, S.Das, O.Fedorov, P.Savitsky, J.E.Debreczeni, O.Gileadi, M.Sundstrom, A.Edwards, C.Arrowsmith, J.Weigelt, F.Von Delft, S.Knapp, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.26 / 1.95
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 56.029, 56.029, 220.089, 90.00, 90.00, 120.00
R / Rfree (%) 17.9 / 23.4

Other elements in 2izs:

The structure of Structure of Casein Kinase Gamma 3 in Complex with Inhibitor also contains other interesting chemical elements:

Fluorine (F) 1 atom
Chlorine (Cl) 3 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Structure of Casein Kinase Gamma 3 in Complex with Inhibitor (pdb code 2izs). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of Casein Kinase Gamma 3 in Complex with Inhibitor, PDB code: 2izs:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in 2izs

Go back to Magnesium Binding Sites List in 2izs
Magnesium binding site 1 out of 2 in the Structure of Casein Kinase Gamma 3 in Complex with Inhibitor


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Casein Kinase Gamma 3 in Complex with Inhibitor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1335

b:38.1
occ:1.00
O A:HOH2053 2.1 29.5 1.0
O A:HOH2071 2.2 18.0 1.0
O A:HOH2052 2.2 34.9 1.0
O A:HOH2032 2.4 33.1 1.0
CG A:GLN101 3.6 17.5 0.5
CD A:GLN101 4.0 21.0 0.5
O A:ILE99 4.1 14.7 1.0
OE1 A:GLU117 4.1 20.5 1.0
O A:HOH2120 4.1 18.9 1.0
NE2 A:GLN101 4.2 11.7 0.5
O A:HOH2056 4.3 9.2 1.0
O A:HOH2118 4.4 23.0 1.0
O A:GLY96 4.4 14.1 1.0
OE1 A:GLN101 4.6 33.9 0.5
CD A:GLU117 4.9 14.4 1.0
OE2 A:GLU117 4.9 17.8 1.0
N A:GLN101 4.9 15.7 1.0
CB A:GLN101 4.9 17.0 0.5
CB A:GLN101 5.0 17.5 0.5

Magnesium binding site 2 out of 2 in 2izs

Go back to Magnesium Binding Sites List in 2izs
Magnesium binding site 2 out of 2 in the Structure of Casein Kinase Gamma 3 in Complex with Inhibitor


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of Casein Kinase Gamma 3 in Complex with Inhibitor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1336

b:50.6
occ:1.00
O A:HOH2107 1.9 24.0 1.0
O A:HOH2114 2.0 33.1 1.0
OD2 A:ASP185 2.1 34.7 1.0
O A:HOH2122 2.4 30.3 1.0
CG A:ASP185 3.3 16.4 1.0
OD2 A:ASP162 3.4 22.3 1.0
O A:HOH2038 3.8 23.6 1.0
NZ A:LYS164 3.8 26.3 1.0
CE A:LYS164 3.9 20.8 1.0
OD1 A:ASP185 3.9 19.3 1.0
OD1 A:ASN167 4.1 19.4 1.0
ND2 A:ASN167 4.1 10.7 1.0
O A:HOH2025 4.1 28.7 1.0
O A:HOH2105 4.1 20.5 1.0
O A:HOH2033 4.3 26.8 1.0
CB A:ASP185 4.4 14.7 1.0
CG A:ASP162 4.4 19.8 1.0
CG A:ASN167 4.5 12.4 1.0
O A:HOH2113 4.6 21.0 1.0
O A:HOH2054 4.7 14.8 0.5
OD1 A:ASP162 4.7 16.9 1.0
O A:HOH2106 4.8 23.5 1.0
O A:HOH2121 4.9 25.6 1.0

Reference:

G.Bunkoczi, E.Salah, P.Rellos, S.Das, O.Fedorov, P.Savitsky, J.E.Debreczeni, O.Gileadi, M.Sundstrom, A.Edwards, C.Arrowsmith, J.Weigelt, F.Von Delft, S.Knapp. Inhibitor Binding By Casein Kinases To Be Published.
Page generated: Wed Aug 14 00:21:25 2024

Last articles

Cl in 4JCM
Cl in 4JBE
Cl in 4JD0
Cl in 4JCP
Cl in 4JC1
Cl in 4JCL
Cl in 4JCK
Cl in 4JBH
Cl in 4JCC
Cl in 4JBG
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy