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Atomistry » Magnesium » PDB 2ouq-2p88 » 2p55 » |
Magnesium in PDB 2p55: X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and MgatpEnzymatic activity of X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp
All present enzymatic activity of X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp:
2.7.12.2; Protein crystallography data
The structure of X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp, PDB code: 2p55
was solved by
J.F.Ohren,
A.G.Pavlovsky,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2p55:
The structure of X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp
(pdb code 2p55). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp, PDB code: 2p55: Magnesium binding site 1 out of 1 in 2p55Go back to![]() ![]()
Magnesium binding site 1 out
of 1 in the X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp
![]() Mono view ![]() Stereo pair view
Reference:
J.A.Spicer,
G.W.Rewcastle,
M.D.Kaufman,
S.L.Black,
M.S.Plummer,
W.A.Denny,
J.Quin,
A.B.Shahripour,
S.D.Barrett,
C.E.Whitehead,
J.B.Milbank,
J.F.Ohren,
R.C.Gowan,
C.Omer,
H.S.Camp,
N.Esmaeil,
K.Moore,
J.S.Sebolt-Leopold,
S.Pryzbranowski,
R.L.Merriman,
D.F.Ortwine,
J.S.Warmus,
C.M.Flamme,
A.G.Pavlovsky,
H.Tecle.
4-Anilino-5-Carboxamido-2-Pyridone Derivatives As Noncompetitive Inhibitors of Mitogen-Activated Protein Kinase Kinase. J.Med.Chem. V. 50 5090 2007.
Page generated: Wed Aug 14 02:03:47 2024
ISSN: ISSN 0022-2623 PubMed: 17880056 DOI: 10.1021/JM0704548 |
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