Magnesium in PDB 2xsx: Crystal Structure of Human Beta Enolase Enob

All present enzymatic activity of Crystal Structure of Human Beta Enolase Enob:
4.2.1.11;

The structure of Crystal Structure of Human Beta Enolase Enob, PDB code: 2xsx was solved by M.Vollmar, E.Krysztofinska, A.Chaikuad, T.Krojer, R.Cocking, F.Von Delft, C.Bountra, C.H.Arrowsmith, J.Weigelt, A.Edwards, W.W.Yue, U.Oppermann, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.39 / 1.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	95.878, 105.531, 106.091, 90.00, 90.00, 90.00
R / Rfree (%)	15.3 / 18.9

The binding sites of Magnesium atom in the Crystal Structure of Human Beta Enolase Enob (pdb code 2xsx). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Human Beta Enolase Enob, PDB code: 2xsx:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Human Beta Enolase Enob


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human Beta Enolase Enob within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg500 b:12.4 occ:1.00 O A:HOH2358 2.1 13.4 1.0 O A:HOH2506 2.1 15.0 1.0 OD2 A:ASP318 2.2 13.3 1.0 O A:HOH2267 2.2 17.1 1.0 OE2 A:GLU293 2.2 10.2 1.0 OD2 A:ASP245 2.3 12.3 1.0 CG A:ASP245 3.1 13.0 1.0 CG A:ASP318 3.2 12.4 1.0 CD A:GLU293 3.4 9.9 1.0 OD1 A:ASP245 3.4 11.5 1.0 CB A:ASP318 3.7 8.9 1.0 NZ A:LYS394 3.9 11.4 1.0 NE2 A:GLN166 4.0 11.8 1.0 O3 A:PO4501 4.0 31.1 1.0 CG A:GLU293 4.2 9.4 1.0 OE1 A:GLU293 4.2 11.3 1.0 OD2 A:ASP294 4.3 11.2 1.0 O A:HOH2440 4.3 30.6 1.0 OD1 A:ASP318 4.3 12.2 1.0 OE2 A:GLU167 4.4 12.0 1.0 CB A:ASP245 4.4 11.8 1.0 CD2 A:LEU341 4.6 10.0 1.0 NZ A:LYS343 4.7 14.5 1.0 CD A:GLU167 5.0 16.0 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Human Beta Enolase Enob


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Human Beta Enolase Enob within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg500 b:13.4 occ:1.00 OD2 B:ASP318 2.1 15.2 1.0 O B:HOH2336 2.1 14.5 1.0 OE2 B:GLU293 2.1 14.7 1.0 OD2 B:ASP245 2.2 12.4 1.0 O B:HOH2514 2.3 13.8 1.0 O B:HOH2254 2.3 20.0 1.0 CG B:ASP245 3.0 14.3 1.0 CG B:ASP318 3.2 14.9 1.0 CD B:GLU293 3.3 13.9 1.0 OD1 B:ASP245 3.3 12.0 1.0 CB B:ASP318 3.6 14.5 1.0 NE2 B:GLN166 3.9 11.3 1.0 NZ B:LYS394 4.0 12.5 1.0 O2 B:PO4501 4.1 24.9 1.0 CG B:GLU293 4.1 14.1 1.0 OE1 B:GLU293 4.2 15.7 1.0 OD2 B:ASP294 4.3 15.9 1.0 OD1 B:ASP318 4.3 13.6 1.0 OE2 B:GLU167 4.3 10.9 1.0 CB B:ASP245 4.4 13.7 1.0 O B:HOH2418 4.4 31.0 1.0 CD2 B:LEU341 4.6 12.0 1.0 NZ B:LYS343 4.7 14.3 1.0 CD B:GLU167 4.9 13.5 1.0

M.Vollmar, E.Krysztofinska, A.Chaikuad, T.Krojer, R.Cocking, F.Von Delft, C.Bountra, C.H.Arrowsmith, J.Weigelt, A.Edwards, W.W.Yue, U.Oppermann. Crystal Structure of Human Beta Enolase Enob To Be Published.