Magnesium in PDB 2zth: Crystal Structure of Holo Form of Rat Catechol-O- Methyltransferase

All present enzymatic activity of Crystal Structure of Holo Form of Rat Catechol-O- Methyltransferase:
2.1.1.6;

The structure of Crystal Structure of Holo Form of Rat Catechol-O- Methyltransferase, PDB code: 2zth was solved by E.Tsuji, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.90 / 2.60
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	32.903, 61.089, 105.369, 90.00, 90.00, 90.00
R / Rfree (%)	18.7 / 28.1

The binding sites of Magnesium atom in the Crystal Structure of Holo Form of Rat Catechol-O- Methyltransferase (pdb code 2zth). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Holo Form of Rat Catechol-O- Methyltransferase, PDB code: 2zth:

Magnesium binding site 1 out of 1 in the Crystal Structure of Holo Form of Rat Catechol-O- Methyltransferase


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Holo Form of Rat Catechol-O- Methyltransferase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg300 b:47.9 occ:1.00 OD1 A:ASN170 2.2 24.6 1.0 OD1 A:ASP141 2.4 25.8 1.0 OD2 A:ASP169 2.6 25.3 1.0 OD2 A:ASP141 3.0 26.9 1.0 CG A:ASP141 3.1 22.9 1.0 CG A:ASN170 3.3 23.2 1.0 CG A:ASP169 3.4 24.4 1.0 ND2 A:ASN170 3.8 21.4 1.0 CG2 A:VAL42 3.8 57.7 1.0 O A:HOH383 3.8 25.8 1.0 CB A:ASP169 4.0 25.2 1.0 OD1 A:ASP169 4.3 21.3 1.0 N A:VAL42 4.5 57.6 1.0 CB A:ASN170 4.5 25.3 1.0 CE A:SAM305 4.5 37.8 1.0 CB A:ASP141 4.6 20.3 1.0 CB A:SAM305 4.9 29.1 1.0 O A:ASP141 4.9 21.5 1.0 CB A:VAL42 5.0 57.4 1.0

E.Tsuji, K.Okazaki, M.Isaji, K.Takeda. Crystal Structures of the Apo and Holo Form of Rat Catechol-O-Methyltransferase J.Struct.Biol. V. 165 133 2009.
ISSN: ISSN 1047-8477
PubMed: 19111934
DOI: 10.1016/J.JSB.2008.11.012