Atomistry » Magnesium » PDB 3brw-3c5h » 3c4w
Atomistry »
  Magnesium »
    PDB 3brw-3c5h »
      3c4w »

Magnesium in PDB 3c4w: Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Atp and Magnesium Chloride at 2.7A

Enzymatic activity of Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Atp and Magnesium Chloride at 2.7A

All present enzymatic activity of Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Atp and Magnesium Chloride at 2.7A:
2.7.11.14;

Protein crystallography data

The structure of Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Atp and Magnesium Chloride at 2.7A, PDB code: 3c4w was solved by P.Singh, J.J.G.Tesmer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.98 / 2.70
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 202.889, 55.054, 122.699, 90.00, 100.82, 90.00
R / Rfree (%) 19.2 / n/a

Other elements in 3c4w:

The structure of Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Atp and Magnesium Chloride at 2.7A also contains other interesting chemical elements:

Chlorine (Cl) 3 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Atp and Magnesium Chloride at 2.7A (pdb code 3c4w). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Atp and Magnesium Chloride at 2.7A, PDB code: 3c4w:
Jump to Magnesium binding site number: 1; 2; 3;

Magnesium binding site 1 out of 3 in 3c4w

Go back to Magnesium Binding Sites List in 3c4w
Magnesium binding site 1 out of 3 in the Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Atp and Magnesium Chloride at 2.7A


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Atp and Magnesium Chloride at 2.7A within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg564

b:18.7
occ:1.00
 O A:HOH623 1.9 3.7 1.0
O1G A:ATP562 1.9 16.8 1.0
O2B A:ATP562 2.0 15.9 1.0
OD1 A:ASP332 2.1 16.3 1.0
O A:HOH575 2.2 2.0 1.0
O A:HOH621 2.2 2.0 1.0
CG A:ASP332 3.1 20.2 1.0
PB A:ATP562 3.2 14.6 1.0
PG A:ATP562 3.3 13.7 1.0
OD2 A:ASP332 3.4 23.0 1.0
O3B A:ATP562 3.6 18.5 1.0
O A:HOH676 3.7 20.9 1.0
O A:HOH616 4.1 4.8 1.0
O1B A:ATP562 4.1 17.5 1.0
O A:HOH573 4.2 11.0 1.0
O3G A:ATP562 4.2 13.1 1.0
NZ A:LYS216 4.2 16.3 1.0
O2G A:ATP562 4.3 20.4 1.0
CB A:ASP332 4.4 18.8 1.0
O3A A:ATP562 4.4 17.7 1.0
N A:GLY334 4.5 19.5 1.0
O2A A:ATP562 4.5 13.5 1.0
CA A:GLY334 4.6 20.1 1.0
CA A:ASP332 4.7 19.8 1.0
OE2 A:GLU235 4.7 28.3 1.0
PA A:ATP562 4.8 16.2 1.0
C A:ASP332 4.9 20.0 1.0
O1A A:ATP562 4.9 18.4 1.0

Magnesium binding site 2 out of 3 in 3c4w

Go back to Magnesium Binding Sites List in 3c4w
Magnesium binding site 2 out of 3 in the Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Atp and Magnesium Chloride at 2.7A


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Atp and Magnesium Chloride at 2.7A within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mg563

b:49.9
occ:1.00
 O2A B:ATP562 2.2 20.5 1.0
OD2 B:ASP332 2.3 22.1 1.0
OD1 B:ASN319 2.4 19.4 1.0
O B:HOH572 2.6 23.6 1.0
CG B:ASP332 3.4 20.8 1.0
O B:HOH573 3.4 22.9 1.0
CG B:ASN319 3.5 18.8 1.0
PA B:ATP562 3.6 19.8 1.0
CB B:ASP332 3.9 20.1 1.0
O3B B:ATP562 4.0 20.1 1.0
O2G B:ATP562 4.0 25.1 1.0
ND2 B:ASN319 4.1 15.2 1.0
O3' B:ATP562 4.2 22.3 1.0
O3G B:ATP562 4.2 23.3 1.0
O1A B:ATP562 4.3 18.0 1.0
PG B:ATP562 4.4 23.8 1.0
O B:GLU318 4.4 18.6 1.0
OD1 B:ASP332 4.5 21.0 1.0
O5' B:ATP562 4.5 17.2 1.0
C3' B:ATP562 4.5 19.1 1.0
O3A B:ATP562 4.7 22.1 1.0
CG B:GLU318 4.7 20.7 1.0
CB B:ASN319 4.8 15.6 1.0
C5' B:ATP562 4.8 21.3 1.0
CA B:ASN319 4.8 16.8 1.0
PB B:ATP562 4.9 18.7 1.0
C B:GLU318 5.0 18.0 1.0

Magnesium binding site 3 out of 3 in 3c4w

Go back to Magnesium Binding Sites List in 3c4w
Magnesium binding site 3 out of 3 in the Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Atp and Magnesium Chloride at 2.7A


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Atp and Magnesium Chloride at 2.7A within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mg564

b:24.7
occ:1.00
 OD1 B:ASP332 2.2 21.0 1.0
O2B B:ATP562 2.4 13.9 1.0
O2G B:ATP562 2.8 25.1 1.0
O B:HOH602 3.2 25.2 1.0
CG B:ASP332 3.4 20.8 1.0
O1G B:ATP562 3.6 24.8 1.0
PG B:ATP562 3.6 23.8 1.0
PB B:ATP562 3.7 18.7 1.0
OD2 B:ASP332 3.8 22.1 1.0
O B:HOH603 3.9 30.1 1.0
O3B B:ATP562 4.0 20.1 1.0
N B:GLY334 4.2 19.7 1.0
CA B:GLY334 4.2 20.1 1.0
NZ B:LYS216 4.3 19.1 1.0
O1B B:ATP562 4.6 18.1 1.0
CB B:ASP332 4.6 20.1 1.0
CA B:ASP332 4.8 19.8 1.0
OE1 B:GLU235 4.8 32.7 1.0
O3A B:ATP562 4.8 22.1 1.0
C B:ASP332 4.9 19.8 1.0
C B:GLY334 5.0 20.6 1.0

Reference:

P.Singh, B.Wang, T.Maeda, K.Palczewski, J.J.Tesmer. Structures of Rhodopsin Kinase in Different Ligand States Reveal Key Elements Involved in G Protein-Coupled Receptor Kinase Activation. J.Biol.Chem. V. 283 14053 2008.
ISSN: ISSN 0021-9258
PubMed: 18339619
DOI: 10.1074/JBC.M708974200
Page generated: Wed Aug 14 09:26:29 2024

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy