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Atomistry » Magnesium » PDB 3dtu-3e35 » 3dv3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 3dtu-3e35 » 3dv3 » |
Magnesium in PDB 3dv3: MEK1 with Pf-04622664 BoundEnzymatic activity of MEK1 with Pf-04622664 Bound
All present enzymatic activity of MEK1 with Pf-04622664 Bound:
2.7.12.2; Protein crystallography data
The structure of MEK1 with Pf-04622664 Bound, PDB code: 3dv3
was solved by
S.L.Kazmirski,
M.Kothe,
Y.-H.Ding,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3dv3:
The structure of MEK1 with Pf-04622664 Bound also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the MEK1 with Pf-04622664 Bound
(pdb code 3dv3). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the MEK1 with Pf-04622664 Bound, PDB code: 3dv3: Magnesium binding site 1 out of 1 in 3dv3Go back to![]() ![]()
Magnesium binding site 1 out
of 1 in the MEK1 with Pf-04622664 Bound
![]() Mono view ![]() Stereo pair view
Reference:
H.Tecle,
J.Shao,
Y.Li,
M.Kothe,
S.Kazmirski,
J.Penzotti,
Y.H.Ding,
J.Ohren,
D.Moshinsky,
R.Coli,
N.Jhawar,
E.Bora,
S.Jacques-O'hagan,
J.Wu.
Beyond the Mek-Pocket: Can Current Mek Kinase Inhibitors Be Utilized to Synthesize Novel Type III Nckis? Does the Mek-Pocket Exist in Kinases Other Than Mek? Bioorg.Med.Chem.Lett. V. 19 226 2009.
Page generated: Wed Aug 14 12:43:47 2024
ISSN: ISSN 0960-894X PubMed: 19019675 DOI: 10.1016/J.BMCL.2008.10.108 |
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