Magnesium in PDB 3g0h: Human Dead-Box Rna Helicase DDX19, in Complex with An Atp-Analogue and Rna

The structure of Human Dead-Box Rna Helicase DDX19, in Complex with An Atp-Analogue and Rna, PDB code: 3g0h was solved by T.Karlberg, L.Lehtio, R.Collins, C.H.Arrowsmith, H.Berglund, C.Bountra, L.G.Dahlgren, A.M.Edwards, S.Flodin, A.Flores, S.Graslund, M.Hammarstrom, A.Johansson, I.Johansson, T.Kotenyova, M.Moche, M.E.Nilsson, P.Nordlund, T.Nyman, C.Persson, J.Sagemark, P.Schutz, M.I.Siponen, A.G.Thorsell, L.Tresaugues, S.Van Den Berg, J.Weigelt, M.Welin, M.Wisniewska, H.Schuler, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.62 / 2.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	41.570, 81.080, 124.740, 90.00, 90.00, 90.00
R / Rfree (%)	21.7 / 27.5

The binding sites of Magnesium atom in the Human Dead-Box Rna Helicase DDX19, in Complex with An Atp-Analogue and Rna (pdb code 3g0h). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human Dead-Box Rna Helicase DDX19, in Complex with An Atp-Analogue and Rna, PDB code: 3g0h:

Magnesium binding site 1 out of 1 in the Human Dead-Box Rna Helicase DDX19, in Complex with An Atp-Analogue and Rna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human Dead-Box Rna Helicase DDX19, in Complex with An Atp-Analogue and Rna within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg476 b:13.8 occ:1.00 O1G A:ANP1 1.9 10.9 1.0 O2B A:ANP1 2.3 12.5 1.0 O3A A:ANP1 2.9 11.8 1.0 PB A:ANP1 3.1 10.7 1.0 PG A:ANP1 3.3 10.8 1.0 OG1 A:THR145 3.6 9.2 1.0 N3B A:ANP1 3.6 12.0 1.0 OD2 A:ASP242 4.1 13.7 1.0 PA A:ANP1 4.1 10.8 1.0 CA A:GLY396 4.1 10.1 1.0 OD1 A:ASP242 4.2 13.5 1.0 O2A A:ANP1 4.3 11.0 1.0 O3G A:ANP1 4.3 11.8 1.0 O2G A:ANP1 4.3 12.2 1.0 O A:GLY396 4.3 10.2 1.0 O1B A:ANP1 4.5 11.9 1.0 O1A A:ANP1 4.5 9.6 1.0 OE1 A:GLU243 4.5 11.3 1.0 CG A:ASP242 4.6 14.0 1.0 C A:GLY396 4.7 10.1 1.0 CE A:LYS144 4.8 7.0 1.0 N A:THR145 4.8 8.9 1.0 NZ A:LYS144 4.9 6.2 1.0 CB A:THR145 4.9 9.0 1.0 NH2 A:ARG432 5.0 12.2 1.0

R.Collins, T.Karlberg, L.Lehtio, P.Schutz, S.Van Den Berg, L.G.Dahlgren, M.Hammarstrom, J.Weigelt, H.Schuler. The Dexd/H-Box Rna Helicase DDX19 Is Regulated By An {Alpha}-Helical Switch. J.Biol.Chem. V. 284 10296 2009.
ISSN: ISSN 0021-9258
PubMed: 19244245
DOI: 10.1074/JBC.C900018200