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Atomistry » Magnesium » PDB 3gnz-3gx2 » 3gwt » |
Magnesium in PDB 3gwt: Catalytic Domain of Human Phosphodiesterase 4B2B in Complex with A Quinoline InhibitorEnzymatic activity of Catalytic Domain of Human Phosphodiesterase 4B2B in Complex with A Quinoline Inhibitor
All present enzymatic activity of Catalytic Domain of Human Phosphodiesterase 4B2B in Complex with A Quinoline Inhibitor:
3.1.4.17; Protein crystallography data
The structure of Catalytic Domain of Human Phosphodiesterase 4B2B in Complex with A Quinoline Inhibitor, PDB code: 3gwt
was solved by
D.O.Somers,
M.Neu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3gwt:
The structure of Catalytic Domain of Human Phosphodiesterase 4B2B in Complex with A Quinoline Inhibitor also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Catalytic Domain of Human Phosphodiesterase 4B2B in Complex with A Quinoline Inhibitor
(pdb code 3gwt). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Catalytic Domain of Human Phosphodiesterase 4B2B in Complex with A Quinoline Inhibitor, PDB code: 3gwt: Magnesium binding site 1 out of 1 in 3gwtGo back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Catalytic Domain of Human Phosphodiesterase 4B2B in Complex with A Quinoline Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
M.D.Woodrow,
S.P.Ballantine,
M.D.Barker,
B.J.Clarke,
J.Dawson,
T.W.Dean,
C.J.Delves,
B.Evans,
S.L.Gough,
S.B.Guntrip,
S.Holman,
D.S.Holmes,
M.Kranz,
M.K.Lindvaal,
F.S.Lucas,
M.Neu,
L.E.Ranshaw,
Y.E.Solanke,
D.O.Somers,
P.Ward,
J.O.Wiseman.
Quinolines As A Novel Structural Class of Potent and Selective PDE4 Inhibitors. Optimisation For Inhaled Administration. Bioorg.Med.Chem.Lett. V. 19 5261 2009.
Page generated: Wed Aug 14 14:58:27 2024
ISSN: ISSN 0960-894X PubMed: 19656678 DOI: 10.1016/J.BMCL.2009.04.012 |
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