Magnesium in PDB 3r7w: Crystal Structure of GTR1P-GTR2P Complex

The structure of Crystal Structure of GTR1P-GTR2P Complex, PDB code: 3r7w was solved by R.Gong, L.Li, Y.Liu, P.Wang, H.Yang, L.Wang, J.Cheng, K.L.Guan, Y.Xu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.06 / 2.77
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	68.908, 148.439, 98.508, 90.00, 100.61, 90.00
R / Rfree (%)	23.6 / 28.3

The binding sites of Magnesium atom in the Crystal Structure of GTR1P-GTR2P Complex (pdb code 3r7w). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Crystal Structure of GTR1P-GTR2P Complex, PDB code: 3r7w:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Crystal Structure of GTR1P-GTR2P Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of GTR1P-GTR2P Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg600 b:62.7 occ:1.00 O A:HOH702 2.0 68.7 1.0 OG A:SER20 2.0 62.5 1.0 O2B A:GNP500 2.1 69.9 1.0 O1G A:GNP500 2.2 73.4 1.0 O A:HOH701 2.2 66.4 1.0 OG1 A:THR41 2.3 67.9 1.0 CB A:SER20 3.0 61.8 1.0 CB A:THR41 3.3 68.3 1.0 PG A:GNP500 3.3 66.1 1.0 PB A:GNP500 3.4 70.0 1.0 N3B A:GNP500 3.6 64.0 1.0 O2A A:GNP500 3.7 67.8 1.0 O3G A:GNP500 3.8 59.4 1.0 N A:SER20 3.9 67.9 1.0 N A:THR41 3.9 69.2 1.0 CA A:SER20 4.0 62.9 1.0 OD2 A:ASP61 4.2 60.1 1.0 CA A:THR41 4.2 70.3 1.0 O1B A:GNP500 4.2 61.3 1.0 OD1 A:ASP61 4.3 62.0 1.0 O A:GLY39 4.3 75.1 1.0 CG2 A:THR41 4.4 65.0 1.0 O3A A:GNP500 4.5 64.2 1.0 O2G A:GNP500 4.6 72.8 1.0 CG A:ASP61 4.6 63.4 1.0 PA A:GNP500 4.7 69.2 1.0 C A:ALA40 4.7 70.8 1.0 C A:LYS19 5.0 68.3 1.0

Magnesium binding site 2 out of 4 in the Crystal Structure of GTR1P-GTR2P Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of GTR1P-GTR2P Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg600 b:0.4 occ:1.00 O2B B:GNP500 2.4 0.1 1.0 O1G B:GNP500 2.5 0.7 1.0 CB B:SER23 2.5 0.5 1.0 OG1 B:THR44 2.7 0.0 1.0 OE1 B:GLU62 2.8 0.3 1.0 OG B:SER23 2.9 0.1 1.0 CB B:THR44 3.2 0.1 1.0 N B:THR44 3.4 1.0 1.0 PG B:GNP500 3.8 1.0 1.0 PB B:GNP500 3.8 0.9 1.0 CA B:THR44 3.8 0.4 1.0 CA B:SER23 3.9 0.8 1.0 CD B:GLU62 4.0 0.6 1.0 N3B B:GNP500 4.1 0.6 1.0 O B:THR44 4.2 0.1 1.0 N B:SER23 4.3 0.4 1.0 O2A B:GNP500 4.4 1.0 1.0 OE2 B:GLU62 4.4 0.2 1.0 C B:THR44 4.4 0.8 1.0 O2G B:GNP500 4.5 0.1 1.0 C B:SER43 4.5 0.5 1.0 CG2 B:THR44 4.6 0.6 1.0 O1B B:GNP500 4.7 0.3 1.0 O3A B:GNP500 4.7 0.2 1.0 CA B:SER43 4.8 0.4 1.0 CG B:LYS22 4.8 0.8 1.0 O3G B:GNP500 4.8 0.3 1.0 PA B:GNP500 4.9 0.5 1.0 C B:SER23 4.9 0.6 1.0 O1A B:GNP500 4.9 0.9 1.0

Magnesium binding site 3 out of 4 in the Crystal Structure of GTR1P-GTR2P Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Crystal Structure of GTR1P-GTR2P Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg600 b:63.3 occ:1.00 O C:HOH702 1.7 66.3 1.0 O C:HOH701 1.9 62.8 1.0 O1G C:GNP500 2.0 65.0 1.0 O2B C:GNP500 2.1 65.6 1.0 OG1 C:THR41 2.2 62.8 1.0 OG C:SER20 2.3 62.0 1.0 CB C:THR41 3.2 62.2 1.0 PG C:GNP500 3.2 62.3 1.0 CB C:SER20 3.3 62.8 1.0 PB C:GNP500 3.4 68.4 1.0 N3B C:GNP500 3.5 61.3 1.0 N C:THR41 3.7 66.9 1.0 O3G C:GNP500 3.7 58.6 1.0 OD2 C:ASP61 4.0 68.8 1.0 N C:SER20 4.0 62.6 1.0 CA C:THR41 4.1 62.3 1.0 O2A C:GNP500 4.1 62.7 1.0 CA C:SER20 4.2 63.9 1.0 O1B C:GNP500 4.2 60.3 1.0 OD1 C:ASP61 4.3 64.9 1.0 CG2 C:THR41 4.4 59.0 1.0 O2G C:GNP500 4.4 65.4 1.0 O3A C:GNP500 4.4 67.0 1.0 CG C:ASP61 4.5 60.9 1.0 O C:GLY39 4.6 77.5 1.0 PA C:GNP500 4.6 66.1 1.0 C C:ALA40 4.7 72.1 1.0 O1A C:GNP500 4.9 67.8 1.0 CA C:ALA40 4.9 70.8 1.0

Magnesium binding site 4 out of 4 in the Crystal Structure of GTR1P-GTR2P Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Crystal Structure of GTR1P-GTR2P Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg600 b:0.6 occ:1.00 OG D:SER23 2.1 0.1 1.0 O1G D:GNP500 2.3 0.5 1.0 CB D:SER23 2.5 0.5 1.0 O2B D:GNP500 2.8 0.1 1.0 N D:SER23 3.4 0.5 1.0 PG D:GNP500 3.4 0.3 1.0 CA D:SER23 3.5 0.1 1.0 O3G D:GNP500 3.5 0.1 1.0 NZ D:LYS22 3.7 0.2 1.0 N3B D:GNP500 3.8 0.5 1.0 PB D:GNP500 3.9 0.3 1.0 CB D:LYS22 4.1 0.3 1.0 CE D:LYS22 4.1 0.9 1.0 C D:LYS22 4.5 0.8 1.0 O1B D:GNP500 4.6 0.9 1.0 C D:SER23 4.7 0.4 1.0 O2G D:GNP500 4.8 0.8 1.0 CG D:LYS22 4.9 0.9 1.0 CA D:LYS22 5.0 0.5 1.0

R.Gong, L.Li, Y.Liu, P.Wang, H.Yang, L.Wang, J.Cheng, K.L.Guan, Y.Xu. Crystal Structure of the GTR1P-GTR2P Complex Reveals New Insights Into the Amino Acid-Induced TORC1 Activation Genes Dev. V. 25 1668 2011.
ISSN: ISSN 0890-9369
PubMed: 21816923
DOI: 10.1101/GAD.16968011