Atomistry » Magnesium » PDB 3rvb-3s8c » 3s5e
Atomistry »
  Magnesium »
    PDB 3rvb-3s8c »
      3s5e »

Magnesium in PDB 3s5e: Crystal Structure of Human Frataxin Variant W155R, One of the Friedreich'S Ataxia Point Mutations

Enzymatic activity of Crystal Structure of Human Frataxin Variant W155R, One of the Friedreich'S Ataxia Point Mutations

All present enzymatic activity of Crystal Structure of Human Frataxin Variant W155R, One of the Friedreich'S Ataxia Point Mutations:
1.16.3.1;

Protein crystallography data

The structure of Crystal Structure of Human Frataxin Variant W155R, One of the Friedreich'S Ataxia Point Mutations, PDB code: 3s5e was solved by C.-L.Tsai, J.Bridwell-Rabb, D.P.Barondeau, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 39.69 / 1.31
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 38.895, 49.215, 67.125, 90.00, 90.00, 90.00
R / Rfree (%) 15.1 / 19.7

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Crystal Structure of Human Frataxin Variant W155R, One of the Friedreich'S Ataxia Point Mutations (pdb code 3s5e). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Human Frataxin Variant W155R, One of the Friedreich'S Ataxia Point Mutations, PDB code: 3s5e:

Magnesium binding site 1 out of 1 in 3s5e

Go back to Magnesium Binding Sites List in 3s5e
Magnesium binding site 1 out of 1 in the Crystal Structure of Human Frataxin Variant W155R, One of the Friedreich'S Ataxia Point Mutations


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human Frataxin Variant W155R, One of the Friedreich'S Ataxia Point Mutations within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1165

b:12.9
occ:0.70
OG1 A:THR119 2.1 11.0 1.0
O A:HOH1164 2.3 23.8 1.0
O A:LYS116 2.4 10.6 1.0
O A:HOH1021 2.4 12.9 1.0
O A:ALA114 2.6 10.6 1.0
O A:THR119 2.7 11.6 1.0
CB A:THR119 3.4 8.6 1.0
C A:THR119 3.4 8.7 1.0
C A:ALA114 3.5 8.9 1.0
C A:LYS116 3.5 9.0 1.0
CA A:THR119 3.7 8.9 1.0
N A:LYS116 3.8 9.1 1.0
N A:THR119 3.8 8.5 1.0
O A:HOH1127 3.9 36.7 1.0
O A:LEU113 4.1 8.7 1.0
CA A:ALA114 4.2 7.4 1.0
C A:ASP115 4.2 8.7 1.0
CA A:LYS116 4.3 9.2 1.0
N A:ASP115 4.4 8.2 1.0
O A:PHE120 4.4 8.7 1.0
CG2 A:THR119 4.5 9.5 1.0
N A:PHE120 4.6 7.6 1.0
N A:PRO117 4.6 10.8 1.0
CA A:ASP115 4.6 8.8 1.0
CA A:PRO117 4.7 11.9 1.0
C A:PRO117 4.7 10.3 1.0
O A:ASP115 4.7 11.5 1.0
C A:PHE120 4.9 8.9 1.0
O A:HOH1026 5.0 13.2 1.0
CB A:LYS116 5.0 9.7 1.0
N A:TYR118 5.0 10.7 1.0

Reference:

C.L.Tsai, J.Bridwell-Rabb, D.P.Barondeau. Friedreich'S Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex. Biochemistry V. 50 6478 2011.
ISSN: ISSN 0006-2960
PubMed: 21671584
DOI: 10.1021/BI200666H
Page generated: Thu Aug 15 10:46:35 2024

Last articles

Fe in 6G7R
Fe in 6G72
Fe in 6G7M
Fe in 6G74
Fe in 6G7Q
Fe in 6G7P
Fe in 6G7N
Fe in 6G71
Fe in 6G2J
Fe in 6G5Q
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy